Medicine
https://openalex.org/C71924100
https://www.wikidata.org/wiki/Q11190
Sagittal plane
https://openalex.org/C178910020
https://www.wikidata.org/wiki/Q2211994
Deformity
https://openalex.org/C2779982284
https://www.wikidata.org/wiki/Q1182746
Coronal plane
https://openalex.org/C13483470
https://www.wikidata.org/wiki/Q1470152
Orthodontics
https://openalex.org/C29694066
https://www.wikidata.org/wiki/Q118301
Osteotomy
https://openalex.org/C2776389721
https://www.wikidata.org/wiki/Q2167748
Surgical planning
https://openalex.org/C2779370443
https://www.wikidata.org/wiki/Q1776627
Rotation (mathematics)
https://openalex.org/C74050887
https://www.wikidata.org/wiki/Q848368
Corrective surgery
https://openalex.org/C2993333090
https://www.wikidata.org/wiki/Q40821
Anatomy
https://openalex.org/C105702510
https://www.wikidata.org/wiki/Q514
Explaining the significance of the current study
This is the first study to …
[INST] Please produce a sentence from the paper. The sentence should not mention the title of the paper, rather it be extracted from the Introducing Work section of the paper.
Please provide one singular full sentence from the paper that serves the function provided, using the example as guidance. Be specific, using relevant terminology from the paper.
Refrain from vague or generic statements. Finally produce a search query in the form of a question targeted towards the knowledge contained therein. 
You must output json with the structure of {'Sentence': sentence, 'Query': query}.
Field: "Orthodontics".
Paper: "The Irregularity Index: A quantitative score of mandibular anterior alignment"
Function: "Explaining the significance of the current study".
Example Sentence: "This is the first study to …". [/INST]