Chemistry
https://openalex.org/C185592680
https://www.wikidata.org/wiki/Q2329
Aryl
https://openalex.org/C2781076698
https://www.wikidata.org/wiki/Q718074
Carbene
https://openalex.org/C2777164566
https://www.wikidata.org/wiki/Q419257
Catalysis
https://openalex.org/C161790260
https://www.wikidata.org/wiki/Q82264
Amination
https://openalex.org/C198503264
https://www.wikidata.org/wiki/Q471635
Medicinal chemistry
https://openalex.org/C155647269
https://www.wikidata.org/wiki/Q243455
Alkyl
https://openalex.org/C2780263894
https://www.wikidata.org/wiki/Q335268
Phenylboronic acid
https://openalex.org/C2777734296
https://www.wikidata.org/wiki/Q408739
Organic chemistry
https://openalex.org/C178790620
https://www.wikidata.org/wiki/Q11351
Combinatorial chemistry
https://openalex.org/C21951064
https://www.wikidata.org/wiki/Q899212
Identifying a controversy within the field of study
One major issue in early X research concerned ...
[INST] Please produce a sentence from the paper. The sentence should not mention the title of the paper, rather it be extracted from the Introducing Work section of the paper.
Please provide one singular full sentence from the paper that serves the function provided, using the example as guidance. Be specific, using relevant terminology from the paper.
Refrain from vague or generic statements. Finally produce a search query in the form of a question targeted towards the knowledge contained therein. 
You must output json with the structure of {'Sentence': sentence, 'Query': query}.
Field: "Medicinal chemistry".
Paper: "Intermolecular Amidation of Unactivated sp 2  and sp 3  C−H Bonds via Palladium-Catalyzed Cascade C−H Activation/Nitrene Insertion"
Function: "Identifying a controversy within the field of study".
Example Sentence: "One major issue in early X research concerned ...". [/INST]