PCSK9, a member of the peptidase S8 family (enzymes that preferentially catalyze the hydrolysis of leucine residues at the N-terminus of peptides and proteins), reveals four major components in the pre-processed protein: the signal peptide ; the N-terminal prodomain; the catalytic domain; and the C-terminal domain.
PCSK9, a member of the peptidase S8 family (enzymes that preferentially catalyze the hydrolysis of leucine residues at the N-terminus of peptides and proteins), reveals four major components in the pre-processed protein: the signal peptide ; the N-terminal prodomain; the catalytic domain; and the C-terminal domain.