The NFKB complex is inhibited by I-kappa-B proteins, phosphorylation (biochemical process that involves the addition of phosphate to an organic compound) of the serine residues of which by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex.
The NFKB complex is inhibited by I-kappa-B proteins, phosphorylation (biochemical process that involves the addition of phosphate to an organic compound) of the serine residues of which by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex.