The NFKB complex is inhibited by I-kappa-B proteins, phosphorylation of the serine residues of which by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex.
The NFKB complex is inhibited by I-kappa-B proteins, phosphorylation of the serine residues of which by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex.