PDX1 cells are necessary in pancreatic development because the fates of pancreatic cells are controlled by downstream transcription factors; PDX1 epithelial cells give rise to pancreatic buds and eventually the whole pancreas.
PDX1 cells are necessary in pancreatic development because the fates of pancreatic cells are controlled by downstream transcription factors; PDX1 epithelial cells give rise to pancreatic buds and eventually the whole pancreas.