UCP2, which is expressed on many different tissues including the kidney, liver, GI tract, brain, and skeletal muscle, separate, or uncouple, oxidative phosphorylation from ATP synthesis by dissipating the mitochondrial membrane potential as heat and they reduce the mitochondrial membrane potential in mammalian cells, which reduces production of reactive oxygen species (ROS).
UCP2, which is expressed on many different tissues including the kidney, liver, GI tract, brain, and skeletal muscle, separate, or uncouple, oxidative phosphorylation from ATP synthesis by dissipating the mitochondrial membrane potential as heat and they reduce the mitochondrial membrane potential in mammalian cells, which reduces production of reactive oxygen species (ROS).