Apurinic/apyrimidinic (AP) sites (pre-mutagenic lesions that can prevent normal DNA replication) occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases.
Apurinic/apyrimidinic (AP) sites (pre-mutagenic lesions that can prevent normal DNA replication) occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases.