CD163 shedding occurs as a result of enzymatic cleavage by ADAM17, and it is upregulated in a large range of inflammatory diseases including liver cirrhosis,  which develops slowly and is often no symptoms.
CD163 shedding occurs as a result of enzymatic cleavage by ADAM17, and it is upregulated in a large range of inflammatory diseases including liver cirrhosis,  which develops slowly and is often no symptoms.