PCSK9, a member of the peptidase S8 family, reveals four major components in the pre-processed protein: the signal peptide; the N-terminal prodomain (has a flexible crystal structure); the catalytic domain; and the C-terminal domain, which is further divided into three modules.
PCSK9, a member of the peptidase S8 family, reveals four major components in the pre-processed protein: the signal peptide; the N-terminal prodomain (has a flexible crystal structure); the catalytic domain; and the C-terminal domain, which is further divided into three modules.