negative feedback generally promotes stability as the overall effect of a negative feedback mechanism.
negative feedback generally promotes stability as the overall effect of a negative feedback mechanism.
what is the overall effect of a negative feedback mechanism?
negative feedback generally promotes stability
whereas positive feedback tends to lead to instability via exponential growth, oscillation or chaotic behavior, negative feedback generally promotes stability. negative feedback tends to promote a settling to equilibrium, and reduces the effects of perturbations. negative feedback loops in which just the right amount of correction is applied with optimum timing can be very stable, accurate, and responsive.
negative feedback
lh supports theca cells in the ovaries that provide androgens and hormonal precursors for estradiol production. at the time of menstruation, fsh initiates follicular growth, specifically affecting granulosa cells. with the rise in estrogens, lh receptors are also expressed on the maturing follicle, which causes it to produce more estradiol. eventually, when the follicle has fully matured, a spike in 17α-hydroxyprogesterone production by the follicle inhibits the production of estrogens, leading to a decrease in estrogen-mediated negative feedback of gnrh in the hypothalamus, which then stimulates the release of lh from the anterior pituitary. however another theory of the lh peak is a positive feedback mechanism from estradiol. the levels keep rising through the follicular phase and when they reach an unknown threshold, this results in the peak of the lh. this effect is opposite from the usual negative feedback mechanism presented at lower levels. in other words, the mechanism(s) are not yet clear.
luteinizing hormone