ghrelin is the hormone that plays a significant role in appetite stimulation.
ghrelin is the hormone that plays a significant role in appetite stimulation.
which hormone plays a significant role in appetite stimulation?
ghrelin
ghrelin only becomes active when caprylic (octanoic) acid is linked posttranslationally to serine at the 3-position by the enzyme ghrelin o-acyltransferase (goat). it is located on the cell membrane of ghrelin cells in the stomach and pancreas. the non-octanoylated form is desacyl ghrelin. it does not activate the ghs-r receptor but does have other effects: cardiac, anti-ghrelin, appetite stimulation, and inhibition of hepatic glucose output. side-chains other than octanoyl have also been observed: these can also trigger the ghrelin receptor. in particular, decanoyl ghrelin has been found to constitute a significant portion of circulating ghrelin in mice, but as of 2011 its presence in humans has not been established.
ghrelin
appetite stimulation is achieved with mga with oral dosages of 400 to 800 mg/day. the optimal dosage with maximum effect for appetite stimulation has been determined to be 800 mg/day. the recommended oral dosage of mga for breast cancer is 40 mg four times per day (160 mg/day total), while the medication is used at an oral dosage of 40 to 320 mg/day in divided doses for endometrial cancer. it has been used at far lower dosages (e.g., 1–5 mg/day oral, 25 mg/month ) in combination with an estrogen for contraceptive purposes.









































section::::medical uses.:available forms.
megestrol acetate