zone of ossification is located on the diaphyseal side of the epiphyseal plate.
zone of ossification is located on the diaphyseal side of the epiphyseal plate.
on the diaphyseal side of the epiphyseal plate is the?
zone of ossification
Na
Na
endochondral ossification is responsible for the initial bone development from cartilage in utero and infants and the longitudinal growth of long bones in the epiphyseal plate. the plate's chondrocytes are under constant division by mitosis. these daughter cells stack facing the epiphysis while the older cells are pushed towards the diaphysis. as the older chondrocytes degenerate, osteoblasts ossify the remains to form new bone. in puberty increasing levels of estrogen, in both females and males, leads to increased apoptosis of chondrocytes in the epiphyseal plate. depletion of chondrocytes due to apoptosis leads to less ossification and growth slows down and later stops when the entire cartilage have become replaced by bone, leaving only a thin epiphyseal scar which later disappears.
epiphyseal plate