superoxide dismutase is found in the body in the blood.
superoxide dismutase is found in the body in the blood.
where is superoxide dismutase found in the body?
blood
superoxide dismutase mimetics









































superoxide dismutase (sod) mimetics are synthetic compounds that mimic the native superoxide dismutase enzyme. sod mimetics effectively convert the superoxide anion (o), a reactive oxygen species, into hydrogen peroxide, which is further converted into water by catalase. reactive oxygen species are natural byproducts of cellular respiration and cause oxidative stress and cell damage, which has been linked to causing cancers, neurodegeneration, age-related declines in health, and inflammatory diseases. sod mimetics are a prime interest in therapeutic treatment of oxidative stress because of their smaller size, longer half-life, and similarity in function to the native enzyme.
superoxide dismutase mimetics
irwin fridovich and joe mccord at duke university discovered the enzymatic activity of superoxide dismutase in 1968. sods were previously known as a group of metalloproteins with unknown function; for example, cuznsod was known as erythrocuprein (or hemocuprein, or cytocuprein) or as the veterinary anti-inflammatory drug "orgotein". likewise, brewer (1967) identified a protein that later became known as superoxide dismutase as an indophenol oxidase by protein analysis of starch gels using the phenazine-tetrazolium technique.
superoxide dismutase