the cytoplasm is the component of cells that is physically connected by a gap junction.
the cytoplasm is the component of cells that is physically connected by a gap junction.
which components of cells are physically connected by a gap junction?
the cytoplasm
bullet::::3. in general, allows transmembrane movement of molecules smaller than 485 daltons (1,100 daltons through invertebrate gap junctions), although different connexin subunits may impart different pore sizes and different charge selectivity. large biomolecules, for example, nucleic acid and protein, are precluded from cytoplasmic transfer between cells through gap junction connexin channels.









































bullet::::4. ensures that molecules and current passing through the gap junction do not leak into the intercellular space.









































to date, five different functions have been ascribed to gap junction protein:









































bullet::::1. electrical and metabolic coupling between cells









































bullet::::2. electrical and metabolic exchange through hemichannels
gap junction
gap junction protein









































gap junction proteins









































bullet::::- gap junction α (gja) proteins









































bullet::::- gja1, gap junction alpha-1 protein









































bullet::::- gja2, gap junction alpha-2 protein









































bullet::::- gja3, gap junction alpha-3 protein









































bullet::::- gja4, gap junction alpha-4 protein









































bullet::::- gja5, gap junction alpha-5 protein









































bullet::::- gja6, gap junction alpha-6 protein









































bullet::::- gja7, gap junction alpha-7 protein









































bullet::::- gja8, gap junction alpha-8 protein









































bullet::::- gja9, gap junction alpha-9 protein









































bullet::::- gja10, gap junction alpha-10 protein









































bullet::::- gja11, gap junction alpha-11 protein









































bullet::::- gja12, gap junction alpha-12 protein









































bullet::::- gap junction β (gjb) proteins









































bullet::::- gjb1, gap junction beta-1 protein
gap junction protein