superoxide dismutase sod2 is found in the body in mitochondria.
superoxide dismutase sod2 is found in the body in mitochondria.
where is superoxide dismutase sod2 found in the body?
mitochondria
sod2 knockout or null mutations cause growth inhibition on respiratory carbon sources in addition to decreased post-diauxic lifespan.









































in the fission yeast "schizosaccharomyces pombe", deficiency of mitochondrial superoxide dismutase sod2 accelerates chronological aging.









































several prokaryotic sod null mutants have been generated, including "e. coli". the loss of periplasmic cuznsod causes loss of virulence and might be an attractive target for new antibiotics.









































section::::role in disease.
superoxide dismutase
superoxide dismutase mimetics









































superoxide dismutase (sod) mimetics are synthetic compounds that mimic the native superoxide dismutase enzyme. sod mimetics effectively convert the superoxide anion (o), a reactive oxygen species, into hydrogen peroxide, which is further converted into water by catalase. reactive oxygen species are natural byproducts of cellular respiration and cause oxidative stress and cell damage, which has been linked to causing cancers, neurodegeneration, age-related declines in health, and inflammatory diseases. sod mimetics are a prime interest in therapeutic treatment of oxidative stress because of their smaller size, longer half-life, and similarity in function to the native enzyme.
superoxide dismutase mimetics