splitting of the corpus callosum is a treatment for refractory epilepsy.
splitting of the corpus callosum is a treatment for refractory epilepsy.
splitting of the corpus callosum is a treatment for?
refractory epilepsy
corpus callosotomy









































corpus callosotomy is a palliative surgical procedure for the treatment of medically refractory epilepsy. in this procedure the corpus callosum is cut through in an effort to limit the spread of epileptic activity between the two halves of the brain. 









































after the operation the brain has much more difficulty sending messages between the hemispheres. although the corpus callosum is the largest white matter tract connecting the hemispheres, some limited interhemispheric communication is still possible via the anterior commissure and posterior commissure.
corpus callosotomy
age-related decline in the commissural fiber tracts that make up the corpus callosum indicate the corpus callosum is involved in memory and executive function. specifically, the posterior fibers of the corpus callosum are associated with episodic memory. perceptual processing decline is also related to diminished integrity of occipital fibers of the corpus callosum. evidence suggests that the genu of the corpus callosum does not contribute significantly to any one cognitive domain in the elderly. as fiber tract connectivity in the corpus callosum declines due to aging, compensatory mechanisms are found in other areas of the corpus callosum and frontal lobe. these compensatory mechanisms, increasing connectivity in other parts of the brain, may explain why elderly individuals still display executive function as a decline of connectivity is seen in regions of the corpus callosum.
commissural fiber