mast cells are located in the blood in the body.
mast cells are located in the blood in the body.
where are mast cells located in the body?
blood
mast cells seem to have other roles as well. because they gather together around wounds, mast cells may play a part in wound healing. for example, the typical itching felt around a healing scab may be caused by histamine released by mast cells. researchers also think mast cells may have a role in the growth of blood vessels (angiogenesis). no one with "too few" or no mast cells has been found, which indicates to some scientists we may not be able to survive with too few mast cells.
mastocytosis
mast cells have toll-like receptors and interact with dendritic cells, b cells, and t cells to help mediate adaptive immune functions. mast cells express mhc class ii molecules and can participate in antigen presentation; however, the mast cell's role in antigen presentation is not very well understood. mast cells can consume and kill gram-negative bacteria (e.g., salmonella), and process their antigens. they specialize in processing the fimbrial proteins on the surface of bacteria, which are involved in adhesion to tissues. in addition to these functions, mast cells produce cytokines that induce an inflammatory response. this is a vital part of the destruction of microbes because the cytokines attract more phagocytes to the site of infection.
phagocyte