the parietal cells of the gastric mucosa secrete hydrochloric acid.
the parietal cells of the gastric mucosa secrete hydrochloric acid.
the parietal cells of the gastric mucosa secrete?
hydrochloric acid
the presence of gastrin stimulates parietal cells of the stomach to secrete hydrochloric acid (hcl)/gastric acid. this is done both directly on the parietal cell and indirectly via binding onto cck2/gastrin receptors on ecl cells in the stomach, which then responds by releasing histamine, which in turn acts in a paracrine manner on parietal cells stimulating them to secrete h+ ions. this is the major stimulus for acid secretion by parietal cells.









































along with the above-mentioned function, gastrin has been shown to have additional functions as well:









































bullet::::- stimulates parietal cell maturation and fundal growth.
gastrin
gastric parietal cells are rich in mitochondria which provide energy in the form of atp for cells by oxidative phosphorylation, critical to maintain the proper morphology and function of gastric mucosa. the mitochondrion is the major target of intracellular oxidative stress associated with aggressive factors like "h. pylori", alcohol and nsaids, which disturb the energy metabolism of mitochondria. troxipide accelerates oxygen intake of marginal gastric mucosa and glycogen consumptive stimulation of the gastric mucosa of the corpus, thereby elevating the tissue respiration and energy metabolism.









































section::::mechanism of action.:stimulation of mucosal microcirculation.
troxipide