acromegly is a disorder due to chronically high levels of growth hormone.
acromegly is a disorder due to chronically high levels of growth hormone.
acromegly is a disorder due to chronically high levels of?
growth hormone
bullet::::- acromegaly is a syndrome that results when the anterior pituitary gland produces excess growth hormone (gh). approximately 90-95% of acromegaly cases are caused by a pituitary adenoma and it most commonly affects middle aged adults, acromegly can result in severe disfigurement, serious complicating conditions, and premature death if unchecked. the disease which is often also associated with gigantism, is difficult to diagnose in the early stages and is frequently missed for many years, until changes in external features, especially of the face, become noticeable with the median time from the development of initial symptoms to diagnosis being twelve years.
pituitary adenoma
research indicates that adult hippocampal neurogenesis is inversely related to major depressive disorder (mdd). neurogenesis is decreased in the hippocampus of animal models of major depressive disorder, and many treatments for the disorder, including antidepressant medication and electroconvulsive therapy, increase hippocampal neurogenesis. it has been theorized that decreased hippocampal neurogenesis in individuals with major depressive disorder may be related to the high levels of stress hormones called glucocorticoids, which are also associated with the disorder. the hippocampus instructs the hypothalamic-pituitary-adrenal axis to produce fewer glucocorticoids when glucocorticoid levels are high. a malfunctioning hippocampus, therefore, might explain the chronically high glucocorticoid levels in individuals with major depressive disorder. however, some studies have indicated that hippocampal neurogenesis is not lower in individuals with major depressive disorder and that blood glucocorticoid levels do not change when hippocampal neurogenesis changes, so the associations are still uncertain.
adult neurogenesis