someone would take a chondroitin sulfate supplement for treatment of osteoarthritis.
someone would take a chondroitin sulfate supplement for treatment of osteoarthritis.
why would someone take a chondroitin sulfate supplement?
for treatment of osteoarthritis
chondroitin sulfate









































chondroitin sulfate is a sulfated glycosaminoglycan (gag) composed of a chain of alternating sugars (n-acetylgalactosamine and glucuronic acid). it is usually found attached to proteins as part of a proteoglycan. a chondroitin chain can have over 100 individual sugars, each of which can be sulfated in variable positions and quantities. chondroitin sulfate is an important structural component of cartilage and provides much of its resistance to compression. along with glucosamine, chondroitin sulfate has become a widely used dietary supplement for treatment of osteoarthritis.









































section::::medical use.
chondroitin sulfate
pharmacokinetic studies performed on humans and experimental animals after oral administration of chondroitin sulfate revealed that it can be absorbed orally. chondroitin sulfate shows first-order kinetics up to single doses of 3,000 mg. multiple doses of 800 mg in people with osteoarthritis do not alter the kinetics of chondroitin sulfate. the bioavailability of chondroitin sulfate ranges from 15% to 24% of the orally administered dose. more particularly, on the articular tissue, ronca et al. reported that chondroitin sulfate is not rapidly absorbed in the gastro-intestinal tract and a high content of labeled chondroitin sulfate is found in the synovial fluid and cartilage.
chondroitin sulfate