after deamination, mostly carbon and hydrogen remain.
after deamination, mostly carbon and hydrogen remain.
after deamination what part of the amino acid remains?
mostly carbon and hydrogen
in the human body, deamination takes place primarily in the liver, however glutamate is also deaminated in the kidneys. in situations of excess protein intake, deamination is used to break down amino acids for energy. the amine group is removed from the amino acid and converted to ammonia. the rest of the amino acid is made up of mostly carbon and hydrogen, and is recycled or oxidized for energy. ammonia is toxic to the human system, and enzymes convert it to urea or uric acid by addition of carbon dioxide molecules (which is not considered a deamination process) in the urea cycle, which also takes place in the liver. urea and uric acid can safely diffuse into the blood and then be excreted in urine.
deamination
much of the oxidative deamination occurring in cells involves the amino acid glutamate, which can be oxidatively deaminated by the enzyme glutamate dehydrogenase (gdh), using nad or nadp as a coenzyme. this reaction generates α-ketoglutarate (α-kg) and ammonia. glutamate can then be regenerated from α-kg via the action of transaminases or aminotransferase, which catalyze the transfer of an amino group from an amino acid to an α-keto acid. in this manner, an amino acid can transfer its amine group to glutamate, after which gdh can then liberate ammonia via oxidative deamination. this is a common pathway during amino acid catabolism.
oxidative deamination