keratoconus ( kc ) is a refraction defect due to irregularities of the surface of the cornea or lens.
keratoconus ( kc ) is a refraction defect due to irregularities of the surface of the cornea or lens.
refraction defect due to irregularities of the surface of the cornea or lens?
keratoconus ( kc )
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Na
based on the similarities between lens and cornea, such as abundant water-soluble enzymes, and being derived from ectoderm, the lens and cornea are thought to be co-evolved as a "refraction unit." gene sharing would maximize light transmission and refraction to the retina by this refraction unit. studies have shown that many water-soluble enzymes/proteins expressed by cornea are identical to taxon-specific lens crystallins, such as aldh1a1/ η-crystallin, α-enolase/τ-crystallin, and lactic dehydrogenase/ -crystallin. also, the anuran corneal epithelium, which can transdifferentiate to regenerate the lens, abundantly expresses ubiquitous lens crystallins, α, β and γ, in addition to the taxon-specific crystallin α-enolase/τ-crystallin. overall, the similarity in expression of these proteins in the cornea and lens, both in abundance and taxon-specificity, supports the idea of co-evolution of lens and cornea through gene sharing.
protein moonlighting