bile comes from the duodenum when you vomit.
bile comes from the duodenum when you vomit.
where does bile come from when you vomit?
the duodenum
prior to secreting any of the bile acids (primary or secondary, see below), liver cells conjugate them with one of two amino acids, glycine or taurine, to form a total of 8 possible conjugated bile acids. these conjugated bile acids are often referred to as bile salts because of their physiologically-important acid-base properties. the pka of the unconjugated bile acids are between 5 and 6.5, and the ph of the duodenum ranges between 3 and 5, so when unconjugated bile acids are in the duodenum, they are almost always protonated (ha form), which makes them relatively insoluble in water. conjugating bile acids with amino acids lowers the pka of the bile-acid/amino-acid conjugate to between 1 and 4. thus conjugated bile acids are almost always in their deprotonated (a-) form in the duodenum, which makes them much more water-soluble and much more able to fulfil their physiologic function of emulsifying fats.
bile acid
it is divided into three sections, a fundus, body and neck. the neck tapers and connects to the biliary tract via the cystic duct, which then joins the common hepatic duct to form the common bile duct. at this junction is a mucosal fold called "hartmann's pouch", where gallstones commonly get stuck. the muscular layer of the body is of smooth muscle tissue that helps the gallbladder contract, so that it can discharge its bile into the bile duct. the gallbladder needs to store bile in a natural, semi-liquid form at all times. hydrogen ions secreted from the inner lining of the gallbladder keep the bile acidic enough to prevent hardening. to dilute the bile, water and electrolytes from the digestion system are added. also, salts attach themselves to cholesterol molecules in the bile to keep them from crystallising. if there is too much cholesterol or bilirubin in the bile, or if the gallbladder doesn't empty properly the systems can fail. this is how gallstones form when a small piece of calcium gets coated with either cholesterol or bilirubin and the bile crystallises and forms a gallstone. the main purpose of the gallbladder is to store and release bile, or "gall". bile is released into the small intestine in order to help in the digestion of fats by breaking down larger molecules into smaller ones. after the fat is absorbed, the bile is also absorbed and transported back to the liver for reuse.
human digestive system