simon beckett was the publisher of written in bone.
simon beckett was the publisher of written in bone.
who is the publisher of written in bone?
simon beckett
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to diagnose osteoporosis, despite the inclusion of bone mineral density (bmd), biological markers and clinical factors of fracture risk, many not detected patients are at risk and many fractures are not explained. bone mineral density is an assessment of the quantity of bone. it does not provide information on bone quality, another important parameter to describe the bone. in addition, clinical risk factors for fracture are at best an indirect assessment of the bone quality. one way to describe the quality of the bone is to assess its microarchitecture. bone microarchitecture is related to the mechanical strength of bone and hence its greater or lesser risk of fracture. indeed, for the same quantity of bone, different mechanically resistant bone structures may exist (few large trabeculae or numerous thin trabeculae that are mechanically stronger). actually, bone loss is often accompanied by a deterioration of bone architecture, resulted in a decreased number of trabeculae, increased inter-trabecular distances, and a loss connectivity of the trabecular meshwork. moreover, reduction of cortical bone thickness and increased porosity accompany trabecular bone loss, and in particular promote the fragility of the femoral neck. osteoporotic bone is called "porous".
trabecular bone score