sars-cov-2 simulations go exascale to avoid spike opening and reveal cryptic pockets across the proteome
sars-cov-2 simulations go exascale to avoid spike opening and reveal cryptic pockets across the proteome
we also observe dramatic conformational changes across the proteome, which reveal over 50 cryptic pockets that expand targeting options for the design of antivirals.", "to address this challenge, over a million citizen scientists banded together through the folding@home distributed computing project to create the first exascale computer and simulate an unprecedented 0.1 seconds of the viral proteome.")