multivalency transforms sars-cov-2 networks into broad and ultrapotent neutralizers
multivalency transforms sars-cov-2 networks into broad and ultrapotent neutralizers
one sentence summary multimerization platform transforms antibodies emerging from discovery screens into potent neutralizers that can overcome sars-cov-2 sequence diversity.", "this multi-specific, multi-affinity antibody (multabody; or mb) platform contributes a new class of medical countermeasures against covid-19 and an efficient approach to rapidly deploy potent and broadly-acting therapeutics against infectious diseases of global health importance.", "here, we used the human apoferritin protomer as a modular subunit to drive oligomerization of antibody fragments and transform antibodies targeting sars- cov-2 into exceptionally potent neutralizers."


































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