sars-cov-2 can infect human fibroblasts organoids
sars-cov-2 can infect human fibroblasts organoids
smirnova and iwasaki, however, note several reports suggesting some ace2 protein in certain patches of the human brain, as well as evidence of coronavirus genetic material inside brain neurons of patients who died during the sars epidemic in china in the early 2000s, indicating that the original sars virus could infect brain cells.", "e. song et al., \"neuroinvasive potential of sars-cov-2 revealed in a human brain organoid model,\" biorxiv , doi: 10.1101/2020.06.25.169946, 2020.", "a brainsphere organoid infected with sars-cov-2, showing the spike protein in green and neuron nuclei in blue lena smirnova, johns hopkins university if infection of the brain can feasibly occur in some people, it's certainly not common, nath stresses.", 


































"in addition, neural organoids lack the blood-brain barrier that would normally confer some degree of protection against most viruses, although iwasaki notes it's possible that sars-cov-2 could circumvent this barrier by entering the brain through the olfactory system, something that's been shown in mice infected with common cold-causing coronaviruses.", "when the tissue was exposed to sars-cov-2, the virus readily infected increasing numbers of cells over the course of four days, suggesting that the coronavirus can use the machinery of neurons to generate more copies of itself."


































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