longitudinal omics in cynomolgus hamsters integrated with human data unravel complexity of moderate immune responses to sars-cov-2.
longitudinal omics in cynomolgus hamsters integrated with human data unravel complexity of moderate immune responses to sars-cov-2.
using the syrian hamster model of self-limited moderate covid-19, we defined the specific roles of endothelial and epithelial cells, among other myeloid and non-myeloid lung cell subtypes, for determining the disease course.", "in depth vascular and pulmonary compartment analyses (i) supported the hypothesis that monocyte-derived macrophages dominate inflammation, (ii) revealed endothelial inflammation status and t-cell attraction, and (iii) showed that cd4+ and cd8+ cytotoxic t-cell responses precede viral elimination.", 


































"comparison of hamster single-cell sequencing and proteomics with data sets from covid-19 patients demonstrated inter- species concordance of cellular and molecular host-pathogen interactions.", "we performed detailed spatiotemporal analyses of cellular and molecular processes in sars- cov-2 infected syrian hamsters.")