antibody responses to sars-cov2 are distinct in children with mis-c compared to adults with covid-19
antibody responses to sars-cov2 are distinct in children with mis-c compared to adults with covid-19
these results suggest a distinct infection course and immune response in children and adults who develop severe disease, with implications for optimizing treatments based on symptom and age.", "moreover, mis-c patients had reduced neutralizing activity compared to both covid-19 cohorts, indicating a reduced protective serological response.", "here, we show distinct antibody (ab) responses in children with mis-c compared to adults with severe covid-19 causing acute respiratory distress syndrome (ards), and those who recovered from mild disease.", 


































"there was a reduced breadth and specificity of anti-sars-cov-2-specific antibodies in mis-c patients compared to the covid patient groups; mis-c predominantly generated igg abs specific for the spike (s) protein but not for the nucleocapsid (n) protein, while the covid-19 cohorts had anti-s igg, igm and iga abs, as well as anti-n igg abs.")