significant expression of furin and ace2 on oral epithelial cells may reduce the efficiency of 2019-ncov entry
significant expression of furin and ace2 on oral epithelial cells may reduce the efficiency of 2019-ncov entry
conclusions based on these findings, we speculated that 2019-ncov could effectively invade oral mucosal cells though two possible routes: binding to the ace2 receptor and fusion with cell membrane activated by furin protease.", "our results indicated that oral mucosa tissues are susceptible to 2019-ncov, which provides valuable information for virus-prevention strategy in clinical care as well as daily life.", "results the bioinformatics results indicated the differential expression of ace2 and furin on epithelial cells of different oral mucosal tissues and the proportion of furin-positive cells was obviously higher than that of ace2-positive cells.", 


































"the s-glycoprotein, which recognized as the key factor for the entry of 2019-ncov into the cell, contains two functional domains: an ace2 receptor binding domain and a second domain necessary for fusion of the coronavirus and cell membranes.")