measuring sars-cov-2 neutralizing antibody activity using pseudotyped and chimeric viruses
measuring sars-cov-2 neutralizing antibody activity using pseudotyped and chimeric viruses
while each surrogate virus exhibited subtle differences in the sensitivity with which neutralizing activity was detected, the neutralizing activity of both convalescent plasma and human monoclonal antibodies measured using each virus correlated quantitatively with neutralizing activity measured using an authentic sars-cov-2 neutralization assay.", "here, we describe a collection of approaches based on sars-cov-2 spike-pseudotyped, single-cycle, replication-defective human immunodeficiency virus type-1 (hiv-1) and vesicular stomatitis virus (vsv), as well as a replication-competent vsv/sars- cov-2 chimeric virus."


































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