sars-cov-2 infection of human ace2-transgenic mice inhibited severe lung inflammation and impaired function
sars-cov-2 infection of human ace2-transgenic mice inhibited severe lung inflammation and impaired function
in summary, we found that sars-cov-2 infection of k18-hace2-transgenic mice supports robust viral replication in the lung, which leads to severe immune cell infiltration, inflammation and pulmonary disease.", "binding of the sars-cov-2 spike protein to human angiotensin i-converting enzyme 2 (hace2) primarily targets the virus to type ii pneumocytes within the lung, resulting in injury, inflammation and subsequent respiratory distress1,2.", "the pathogenicity of sars-cov-2 in hace2 transgenic mice."


































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