trim28 regulates sars-cov-2 cell apoptosis by targeting ace2
trim28 regulates sars-cov-2 cell apoptosis by targeting ace2
our study identified trim28 as a novel regulator of ace2 expression and sars-cov-2 cell entry.", "the expression level of ace2 potentially determine the susceptibility and severity of covid-19, it is thus of importance to understand the regulatory mechanism of ace2 expression.", "this study showed that knockdown of trim28 induces ace2 expression and increases pseudotyped sars- cov-2 cell entry of a549 cells and primary pulmonary alveolar epithelial cells (paepics).")