How many enzymes do not have any interactions?
CREATE TABLE enzyme (
    id VARCHAR,
    enzyme_id VARCHAR
)

CREATE TABLE medicine_enzyme_interaction (
    id VARCHAR,
    enzyme_id VARCHAR
)
SELECT COUNT(*) FROM enzyme WHERE NOT id IN (SELECT enzyme_id FROM medicine_enzyme_interaction)
Below are sql tables schemas paired with instruction that describes a task. Using valid SQLite, write a response that appropriately completes the request for the provided tables. ### Instruction: How many enzymes do not have any interactions? ### Input: CREATE TABLE enzyme (
    id VARCHAR,
    enzyme_id VARCHAR
)

CREATE TABLE medicine_enzyme_interaction (
    id VARCHAR,
    enzyme_id VARCHAR
) ### Response: SELECT COUNT(*) FROM enzyme WHERE NOT id IN (SELECT enzyme_id FROM medicine_enzyme_interaction)