a. Updating of the National Climate Change Policy of Panama to 2050 and formulation of the Framework Law on Climate Change, b. Formulation of the Low Carbon Economic and Social Development Strategy by 2050, and The waste sector is greatest potential strengthening at an institutional and regulatory level. Therefore, two (2) actions are presented: The Zero Waste Program 2015-2035 of the Municipality of Panama and the National Plan for Comprehensive Waste Management 2017-2027 from the Urban and Household Cleaning Authority (AAUD). Subsequently, this document includes mitigation actions from the private sector and the Panama Canal operations.