 In an interview with MSNBC, bassist Pete Wentz told Chicagoan/Today Staffer Devin Johnson, that the band was to film the video for the song in Uganda, and further noted, "...we're going to shoot it on 24p cameras and donate the money that we were going to use in the video for the film or the video to a project over there..." According to "Billboard", the band shot the video for the single after having performed their first show in South Africa.The music video was directed by Alan Ferguson.A sneak peek of the video aired on "TRL" on September 12th, and the music video for "Me + You" can now be seen in its entirety on AOL.com.