 Depending upon their location, ependymal cells may display 2 cell poles.A luminal pole projects
to the ependymal lining of a ventricle and a “submesenchymal pole” projects toward the surface of the brain demonstrating glial processes and peripherally situated footplates.Frieda and Pollak conceptualize the architecture of ependymomas as
a primitive neural tube turned inside out with the submesenchymal poles converging toward a central vessel, thus forming a pseudorosette rather than projecting centrifugally toward the pia.