 AcrIIC2 has been shown not to be the only one capable of blocking DNA binding.There are 11 other Acr family proteins that can also carry it out.Some among those are AcrIF1, AcrIF2, and AcrIF10, which act on different subunits of the Cascade effector complex of the type I‐F CRISPR‐Cas system, preventing the DNA to bind to the complex.