 This work is motivated by a critical challenge in characterizing cell-based therapies, namely what should be measured that will provide predictive information about the cell product to assure desirable functionality.Carrying out this study involves a large number of NIST collaborators to address challenges in rapid non-perturbing quantitative imaging, CRISPR-Cas genome editing of reporter iPSC lines, image analysis including the use of CNN inference, and theoretical modeling.In 1991 and 2011, Plant received the Department of Commerce Bronze Medal.