 Antoine joined the Johns Hopkins University Applied Physics Lab in 1998 and has worked there in technical roles, later moving into leadership and program roles.In 2001, as an analytical chemist with the Research and Technology Development Center, she was recognized at the Women of Color Government and Defense Technology Awards Conference as a "rising star".An expert in mass spectrometry, Antoine was part of a team that was recognized in 2009 with an "Invention of the Year" award by the Johns Hopkins Applied Physics Lab for a system that used laser desorption and mass spectrometry to quickly identify potential pathogens in a substance.