 This study has developed into a 30-year study of the management of congestive heart failure with the ubiquinone form of Coenzyme Q10.It has shown that heart failure patients who received Coenzyme Q10 supplementation together with their conventional medications have a significantly better survival than patients who receive placebo supplementation together with their conventional medications.Moreover, in 1986, Judy published the results of a double-blind, crossover study of the effect of Coenzyme Q10 on patients with cardiac disease.