 The heterogeneity of cellular phenotypes within isogenic populations provides a window into the diversity of ways the cellular machinery can operate to process information.This diversity of expression reflects the stochastic fluctuations that occur as connected network variables interact with one another to effect up- and down-regulation.Plant's lab goals include to measure the kinetic constants for those fluctuations, and the correlations between them, to provide a thermodynamic basis for understanding which cellular measurands are the most important for controlling a particular phenotype.