 In 1998, Judy reported the results of a study of Coenzyme Q10 supplementation of chronic fatigue syndrome patients.Two groups of patients, similar in age, exercise tolerance, and duration of illness were given 100 milligrams and 300 milligrams of Coenzyme Q10, respectively.60% of the patients in the 100-milligram group responded to the treatment; 91% of the patients in the 300-milligram group responded.