 Reyers split the 2018 minor league season between Altoona and the Indianapolis Indians, hitting a combined .284/.337/.421/.759 with 8 home runs and 41 RBI.On September 1, 2018, the Pirates selected Reyes' contract and called him up to the majors leagues for the first time.In 13 games with the Pirates, he hit .293/.349/.483/.832 with 3 home runs and 7 RBI.