 This allows a switch between catabolism and anabolism.In 2016, it was established that RagA and Lamtor4 were key to microglia functioning and biogenesis regulation within the lysosome.Further studies also indicate that the Ragulator-Rag complex interacts with proteins other than mTORC1, including an interaction with v-ATPase, which facilitates functions within microglia of the lysosome.