 Reyes made the Pirates Opening Day roster in 2019, and hit .203/.274/.322/.596 with 2 home runs and 17 RBI over 71 games.Reyes was designated for assignment on January 9, 2020, following the signing of Guillermo Heredia.Suspended by MLB for the first 80 games of the 2020 season due to the use of the use of a Performance Enhancing Drug (PED).