 This discovery also led to the first use of the term “Rag-Ragulator” complex, because of the interaction between these two.The amino acid level, cell growth, and other important factors are influenced by the mTOR Complex 1 pathway.On the lysosomal surface, the amino acids signal the activation of the four Rag proteins (RagA, RagB, RagC, and RagD) to translocate mTORC1 to the site of activation.