 In Week 15 of the 2019 season against the Los Angeles Chargers, starting running back Dalvin Cook left the game with a shoulder injury which increased Boone's playing time as a result.During the game, Boone rushed 13 times for 56 yards and two touchdowns in the 39–10 win.In Week 17 against the Chicago Bears, Boone rushed 17 times for 148 yards and a touchdown during the 21–19 loss.