 Aymara dominance in the region was however eventually challenged by the growing state of the Quechuas from Cuzco, who finally conquered them between 1460 and 1500 AD.The Incas conquered much of what is now western Bolivia under their ninth emperor Pachacuti Inca Yupanqui, whose reign lasted from 1438 to 1471 AD.Pachacuti Yupanqui was then succeeded by his son Topa Inca Yupanqui whose reign lasted from 1471 to 1493 AD.