 On 20 May, Caballero played 55 minutes of the first-leg of the quarter-final, before being replaced by Sergio Fernandez, in Cerro Porteño's 2–0 away defeat.In the return leg on 27 May, Caballero would play 69 minutes of the match before being replaced by Oscar Ferreira, as Cerro Porteño would win 3–0 and qualify for the semi-finals with a 3–2 aggregate score line.At the semi-final stage, Cerro Porteño faced Ecuador's Barcelona Sporting Club.