 A period of relative peace between the Powhatans and the settlers ended not long after the death of his brother, Wahunsonacock, when Opechancanough became the new chief.Beginning with the Indian massacre of 1622, Chief Opechancanough gave up on diplomacy with the English settlers of the Colony and Dominion of Virginia and tried to force them to abandon the region both then and again in 1644, when he was captured.Opechancanough was later killed by a soldier assigned to guard him.