 He began the 2015 season on the 15-day disabled list and made his season debut on April 19, 2015.On January 7, 2016, Span signed a three-year, $31 million, contract with the San Francisco Giants that included a mutual option for 2019 and $5 million in performance bonuses.On June 13 at AT&T Park, Span became the first San Francisco Giant to hit a leadoff splash hit home run in the first inning into McCovey Cove and joined the San Diego Padres' Brian Giles () as the only two players in the history of the ballpark to accomplish the feat.