 Because this cofactor is used in low oxygen environments, many helminth-like organisms have adapted to survive host environments such as the areas within the gastrointestinal tracks.Currently the biosynthesis of RQ is still being debated, but there are two main biosynthetic pathways that are being researched.First, is the need for the organism to produce Ubiquinone (UQ) so that the amine group can be added onto the quinone ring.