 Payssé was part of the Human Rights, Budget, and Special Commissions on Gender and Equity, Special Commission for Monitoring the Prison Situation of the General Assembly, and was also a member of the Bicameral Women's Bank which is made up of legislators from all the political parties of Uruguay.She joined the Mercosur Parliament for the period 2010–2015.In a 2010 debate she argued against the use of the theory of the two demons when interpreting the Law on the Expiration of the Punitive Claims of the State.