 St Patrick's Cemetery is of State significance for its long and continuous links with the Catholic community of the Parramatta region that date from November 1788 with the establishment of Parramatta as the second mainland settlement of the colony of NSW.A burial register from 1840 suggests that people made great efforts to bring the dead from outlying areas (as far away as Liverpool, Windsor, Wilberforce, Colo and Berrima) to St Patrick's Cemetery, rather than bury them in nearer but non-Catholic cemeteries.The cemetery contains evidence of burials from a comprehensive cross section of Catholic society in the Parramatta region from the 1820s, with all classes and levels represented.