 The highway passes along the edge of the town of Queenstown, where the highway meets MD 18 (Main Street) and MD 456 (Del Rhodes Avenue) at a pair of superstreet intersections.Access from southbound US 301 to eastbound US 50 and from westbound US 50 to northbound US 301 is via MD 18 at the Queenstown Premium Outlets.US 301 gradually curves northeast as it passes to the south and east of Centreville, the county seat of Queen Anne's County.