 With the arrival of Katharine Hepburn at RKO, Twelvetrees left the studio to freelance (Harding and Bennett would also subsequently depart).The 1930 film "Her Man" set the course of her screen career, and she was subsequently cast in a series of roles portraying suffering women fighting for the wrong men.Later she played opposite Spencer Tracy in 1934's "Now I'll Tell" (also known as "When New York Sleeps") from a novel by Mrs. Arnold Robinson; opposite Donald Cook in "The Spanish Cape Mystery"; and costarred in Paramount's "A Bedtime Story" with Maurice Chevalier.