 Seltzer was Chief Technical Officer of Sleepycat Software (developers of the Berkeley DB embedded database) from 1996 until Sleepycat was acquired by Oracle Corporation in 2006.She served as an architect on the Oracle Berkeley DB team for several years before transferring to Oracle Labs where she continues to act as an architect.Seltzer was a director of USENIX from 2005 to 2014, serving as vice president for one year and president for two.