 The highway has a five-ramp partial cloverleaf interchange with MD 213 (Centreville Road) south of town and a dumbbell interchange with MD 304 (Ruthsburg Road) north of Mill Stream Branch.US 301 has an oblique at-grade crossing of the Centerville Branch of the Northern Line of the Maryland and Delaware Railroad.The highway parallels the railroad through an intersection with MD 305 (Hope Road) at Carville and unsigned MD 834 (Hayden Clark Road), where the median temporarily widens for the Bay Country Welcome Center.