 A longtime Republican, Mosbacher served as a co-chair of the Republican National Committee’s Finance Committee, and she has furthermore been involved with the National Republican Senatorial Committee and the New Republican Majority Fund.She was New York State’s Republican National Committeewomen for more than a decade, and was also the first woman to serve as the general chairman of the Republican Governors Association, a role she continued to hold as of 2001.Mosbacher was a presidential appointee to the US Advisory Board for Trade Policy and Negotiations, a gubernatorial appointee as a New York Commissioner of Racing, and a mayoral appointee for trustee of the New York Hudson River Park Trust.