eOpioidBehavioralFinancialGamblingShoppingPalatable foodSex-relatedIntercoursePornographyInternet-relatedInternet addiction disorderInternet sex addictionVideo game addictionDigital media addictionsCellularmechanismsTranscriptionalΔFosBc-FosCdk5CREBGluR2NF-κBEpigeneticG9aG9a-like proteinHDAC1HDAC2HDAC3HDAC4HDAC5HDAC9HDAC10SIRT1SIRT2...DependenceConceptsPhysical dependencePsychological dependenceWithdrawalDisordersDrugsAlcoholismAmphetamineBarbiturateBenzodiazepineCaffeineCannabisCocaineNicotineOpioidNon-drug stimuliTanning dependenceTreatment and managementDetoxificationAlcohol detoxificationDrug detoxificationBehavioral therapiesCognitive behavioral therapyRelapse preventionContingency managementCommunity reinforcement approach and family trainingMotivational enhancement therapyMotivational interviewingMotivational therapyPhysical exerciseTreatment programsDrug rehabResidential treatment centerHeroin-assisted treatmen