 
 <prompt> Which one happen later, the start of intermittent warfare or the smallpox epidemic? Given di previous question, write a context wey contain di answer. E fit be 1 - 20 sentences. Context: <response>: Intermittent warfare wey start from July 23, 1670 reach July 1695, plus the typhoons of 1671 and 1693, and especially the smallpox epidemic of 1688, reduce the Chamorro population from 50,000 to 10,000 to less than 5,000. Precipitated by the death of Quipuha, and the murder of Father San Vitores and Pedro Calungsod by local rebel chief Matapang, tensions lead to plenty conflicts. Captain Juan de Santiago start campaign to pacify the island, wey other commanders of the Spanish forces continue. 