 
 <prompt> How RNA and DNA dey bind pass? Given di last question, write one context wey contain di answer. E fit be 1 - 20 sentences. Context: <response>: Additionally, genes fit get regulatory regions wey dey many kilobases for front or back of the open reading frame. Dem dey work by binding to transcription factors wey go make the DNA to loop so that the regulatory sequence (and bound transcription factor) go dey close to the RNA polymerase binding site. For example, enhancers dey increase transcription by binding an activator protein wey go help to recruit the RNA polymerase to the promoter; on the other hand, silencers dey bind repressor proteins and make the DNA less available for RNA polymerase. 