 
 <translate> The relevant information is: The Great Plague, lasting from 1665 to 1666, was the last major epidemic of the bubonic plague to occur in England. The answer is 1665 to 1666. <ibo> Ihe ọmụma dị mkpa bụ: Oké Ọrịa Na-efe Efe, nke dịruru site na 1665 ruo 1666, bụ oké ọrịa na-efe efe ikpeazụ nke ọrịa na-efe efe bụ́ nke mere n'England. Azịza ya bụ 1665 ruo 1666. 