 
 <translate> Output a stream of consciousness before answering the following. Passage: Paracelsus (1493 -- 1541) developed the concept, writing that "Nature marks each growth ... according to its curative benefit", and it was followed by Giambattista della Porta in his Phytognomonica (1588).

Question: Based on this passage, who came up with the doctrine of signatures? <ibo> Mee ka uche gị dịrị n'ihe ị na-ekwu tupu ị zaa ajụjụ ndị a. Passage: Paracelsus (1493 - 1541) mepụtara echiche ahụ, na-ede na "Nature na-akara uto ọ bụla... dịka uru ọgwụgwọ ya si dị", Giambattista della Porta gbasoro ya na Phytognomonica ya (1588).  Ajụjụ: Ònye chepụtara ozizi nke akara aka n'ihi ihe e kwuru n'amaokwu a? 