title: 67 CF patients with a declining FEV(1): At risk for acquisition of Burkholderia cepacia complex infection?

text: INTRODUCTION: Burkholderia cepacia complex (Bcc) infection is considered to be associated with worsening of CF lung disease. Patient to patient spread has been reported, however mechanisms of acquisition of Bcc are not well understood. Method: Data from the Belgian CF Registry (year 2000–2010) were collected. Inclusions: Bcc infected patients with entries on lung function in at least 1 y before and 3 y after Bcc acquisition. For each case, we included 2 controls, matched for age at the index year (year of first Bcc infection), pancreatic status, sex. Cumulative data up to 2 years before index year were compared to values obtained after infection using Rank sum test. Rate of decline in lung function was adjusted for baseline lung function, age, sex. RESULTS: Bcc prevalence in CF is low in Belgium (<3%). 183 patients were included: 61 cases, 122 controls. 59% were F508del homozygous. Mean age in cases was 20.9 y (SD 10.5) vs 20.3 y (SD 10.3) in controls. Among the Bcc, 54% were unspecified, 31% were B. multivorans. Mean FEV(1) at index year was 65.2% (SD 24.9) in cases vs 73.1 (SD 26.9) in controls (p = 0.07). FEV(1) decline before index year was significantly higher in cases (–1.7%, SD 0.5) compared to controls (–1.0%, SD 0.3) (p = 0.002). FEV(1) slopes were comparable in the period after index year (–1.1%, SD 0.5, in cases vs –0.99%, SD 0.4, p = 0.24). CONCLUSION: Our results suggest that a declining FEV(1) precedes acquisition of Bcc and may be a risk factor. After acquisition, lung function decline was comparable in Bcc infected and uninfected patients. These results should be interpreted with caution, since registry data are collected retrospectively and bear a risk of incompleteness or inaccuracy.


Highlights from the 20th ECCMID


The dictionary of virology


Cumulative Keyword Index for Volumes 114-117


SARS in context: memory, history, policy


ProMED Update


149* 2009 H1N1 influenza A in cystic fibrosis patients. A French collaborative study


Coping with pain: The impact of SARS visitation restrictions on patients' perception of nursing support


Virus detection made easy: Nanotechnology


SARS source back on the menu


PIV-28 Detection of respiratory viruses by molecular methods – a way of improving conventional diagnosis


Travel Medicine


EPS4.4 Correlation between long-term changes in LCI, FEV(1) and CFCT score in children with cystic fibrosis


Middle East respiratory syndrome (MERS 2012): roles of clinical pathology laboratory for screening and diagnosis


Effective Intervention and Vaccination Strategies Against Nosocomial Infection Based on Network Analysis


A novel coronavirus emerges


Root growth and cyclin control: Doerner, P., Jørgensen, J-E., You, R., Steppuhn, J. and Lamb, C. (1996) Control of root growth and development by cyclin expression, Nature 380, 520–523


Bayer molecular: viral load testing today and tomorrow


Peter Salama


Middle East respiratory syndrome coronavirus conference


Pathogen identification in travelling patients with severe acute respiratory infections from the Middle East to the Philippines, 2014–2016


IF-01 Rapid and Sensitive Detection of Various Influenza Virus Subtypes Using SAT


Author index volume 7 international journal of infectious diseases


Association for Molecular Pathology 2006 Annual Meeting Abstracts


Herpes simplex (HSV) viral load in bronchoalveolar lavage: risk factors and clinical outcome


Respiratory Pathogen Evaluation for Lipschütz Ulcer


Contents-cover detailsi


K.01 Emerging viruses: From clinical virology to virus ecology


PIN12 - HOSPITALIZATIONS RELATED TO RESPIRATORY VIRAL INFECTIONS DURING THE 2017/18 SEASON IN THE VALENCIA REGION OF SPAIN


PP-182 Systematic study the clinic characters of a local measles outbreak in East China


Hepatobiliary & Pancreatic Diseases International (HBPD Int). Table of Contents Vol. 4, No. 1, 2005


Subject index (vol. 90)


THE RETROSPECTIVE ANALYSIS OF GLUCOCORTICOSTEROIDS USE IN THE TREATMENT OF SARS IN BEIJING


Coronaviruses and their diseases. Advances in experimental medicine and biology, Volume 276: Edited by D. Cavanagh & T. D. K. Brown. New York and London: Plenum Press. 1990. 676 pp. US$155.40


FEBS Letters


Infection precautions


Comparison of enzyme-linked immunosorbent assay and western blotting in the detection of anticryptosporidial antibodies in the investigation of a waterborne outbreak of cryptosporidiosis


List of Contents, Author, and Keyword Indices, Vol 29, 2005


Contents of Volume 143


Asian–Oceanian textbook of radiology: By W. C. G. Peh and Y. Hiramatsu. Hardcover, 1300 pp. TTG Asia Media, Singapore, 2003. Price US$120, €98


Pyogranulomatous Pleuropneumonia and Mediastinitis in Ferrets Associated with Chryseomonas-like Bacteria


Exercise Limitation in Survivors of Severe Acute Respiratory Syndrome (SARS)


Community-Acquired Respiratory Virus Infections During the First Year After Lung Transplantation


Respiratory Infection Routes of MERS-CoV in Rabbits


P241 Validation of APPS tool to predict mortality in moderate and severe acute respiratory distress syndrome


To Disclose the Anti-Infection/Inflammatory Mechanism of Terpenoids From Houttuynia Cordata in Virtue of Molecular Simulation


Contents of Volume 151


CHARACTERISTICS AND OUTCOMES AMONG PATIENTS WITH RESPIRATORY VIRUS INFECTIONS DURING THE FIRST YEAR AFTER LUNG TRANSPLANTATION


The veterinary formulary. Handbook of medicines used in veterinary practice: Edited by Yolande Debuf London: The Pharmaceutical Press. 1991. 448 pp. £37.50 (hard)


Pulmonary Function in Survivors of Severe Acute Respiratory Syndrome (SARS)


PULSED METHYLPREDNISOLONE USAGE IN ARDS DUE TO VIRAL PNEUMONIA


The Use of Drotrecogin Alfa (activated) in a Patient With Severe Acute Respiratory Syndrom


title: Binding and entry of animal viruses

text: Viruses are infectious agents capable of packaging and delivering nucleic acids and proteins to specific populations of cells. To initiate infection, viruses bind to sites, or receptors, on the cell surface and transfer their genome across the limiting membrane of the cell. The mechanisms underlying these events, and viral tropism for particular host cells, are becoming increasingly well understood. Several cell surface proteins have now been identified as viral receptors, and analyses of intact virus particles and sub-viral components are revealing the structures of the binding determinants on the viruses themselves. For many viruses, the events leading to penetration and delivery involve constitutive endocytic properties of the host cell, and the low pH environment in endocytic compartments is a crucial trigger in the penetration process. The knowledge of viral tropism, binding and entry suggests strategies which may be applied to the design of targeted therapeutic agents with appropriate specificities and effective delivery mechanisms.


Techniques for the Brucellosis laboratory: G. G. Alton, L. M. Jones, R. D. Angus & J. M. Verger Versailles Cedex: INRA Publications. 1988. 192pp. Ff 195


The role of Cryptosporidium parvum-derived phospholipase in mediating enteric host cell invasion in vitro


Author index to volume 87


Flu: The Story of the Great Influenza Pandemic of 1918 and the Search for the Virus That Caused It


Infection and immunity in farm animals: Edited by R. Pandey Basel: S. Karger. 1985. 255 pp. SFr. 164


Subject Index: TO FOLLOW


SUBJECT INDEX Volume 125 (JANUARY–JUNE, 2004)


Imaging in SARS


Viral Infections and Inflammatory Bowel Disease


Master Author Index


Contents and index of volume 113, July to November 1995


Comparison of the Mortality Prediction of Different ICU Scoring Systems (APACHE II and III, SAPS II, and SOFA) in Acute Respiratory Distress Syndrome Patients


Author index to volume 282


DASATINIB-RELATED CHYLOTHORAX


Cumulative subject index volumes 24–25


Enteric viral infection in patients with the acquired immunodeficiency syndrome: A case of diarrhea?


Liquid column chromatography


Animal health 1984—Report of the chief veterinary officer: London: HMSO. 159 pp. £9.30


Anaesthesia and Intensive Care A-Z–An Encyclopaedia of Principles and Practice


IMAGINATION OF THE IMAGES WHEN VIRUSES ATTACK THE LUNGS


High Dose Intravenous Methylprednisolone in the Treatment of Severe Acute Respiratory Syndrome: A Case Repor


Cell Tropism of Middle East Respiratory Syndrome Coronavirus in Experimentally Infected Dromedaries


Anesthesia and Uncommon Diseases


AGA abstracts T1786–W1189


Corrigendum to “Individual and common inhibitors of coronavirus and picornavirus main proteases” [FEBS Lett. 583 (2009) 549–555]


Tissue Distribution of the Mers-Coronavirus Receptor in Bats


Evolution and tumor pathology of the neuroendocrine system. Fernström foundation series


Master Subject Index


The Novel Human Coronavirus EMC Causes Disease in Macaques but not in Ferrets


Campylobacter infection in man and animals


Toxicological evaluation of certain veterinary drug residues in food: Prepared by The 36th Meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). WHO food additive series: 27 Geneva: WHO 1211 Geneva 27, Switzerland/London: HMSO Books. 1991. 227 pp. Sw.fr. 25. (paper)


Effect of human recombinant interferon-γ on Salmonella typhimurium invasion in cultured human intestinal cells


Nonbacterial respiratory infections


An Uncommon Cause of Adult Respiratory Distress Syndrome


Horses in health and disease: J. L. Naviaux Philadelphia: Lea and Febiger/Beckenham, Kent: Quest-Meridien Ltd. 1985. 300 pp. $27


THE LONG-TERM IMPACT OF SEVERE ACUTE RESPIRATORY SYNDROME (SARS) ON PULMONARY FUNCTION, EXERCISE CAPACITY, AND QUALITY OF LIFE IN A COHORT OF SURVIVORS


The First Outbreak of Porcine Epidemic Diarrhoea in Slovenia: A Signal of Emerging Disease?


Contents and index of volume 119, july to november 1998


Contents of volume 87


Contents of Volume 138


Bovine Histophilosis in Southern Brazil


Mers Coronavirus Infection in Dromedary Camels


Subject index to volume 104


Subject index to volume 87


Contents of Volumes 166 to 173


Virus diseases in laboratory and captive animals: Edited by Gholamreza Darai Dordrecht: Martinus Nijhoff/Kluwer Academic Publishers. 1988. 568 pp. £96.50


Cumulative subject index volumes 52–53


RARE CASE OF MORTALITY FROM NON-CIRRHOTIC HYPERAMMONEMIA


title: The EMPOWER-SUSTAIN e-Health Intervention to improve patient activation and self-management behaviours among individuals with Metabolic Syndrome in primary care: study protocol for a pilot randomised controlled trial

text: BACKGROUND: Epidemiological studies conducted in various parts of the world have clearly demonstrated that metabolic syndrome (MetS) is an increasing global health problem, not only in Western societies but also in Asian populations. Web-based and mobile phone-based self-management applications have been proven to be effective in improving self-management behaviour of patients with MetS components (i.e., diabetes or hypertension). However, evidence is lacking in terms of their effectiveness specifically for patients with MetS. The aim of this pilot study is to evaluate the feasibility and potential effectiveness of the EMPOWER-SUSTAIN Self-Management e-Health Intervention in improving activation and self-management behaviours among patients with MetS. This paper presents the study protocol. METHODS: A pilot randomised controlled trial will be conducted in a university primary care clinic. A total of 232 patients aged 18–60 years with MetS will be recruited; 116 will be randomised to receive the EMPOWER-SUSTAIN intervention for 6 months, and another 116 patients will continue with usual care. The EMPOWER-SUSTAIN intervention is a multifaceted chronic disease management strategy based on the Chronic Care Model and persuasive technology theory. It consists of training primary care physicians, nurses and patients to use the EMPOWER-SUSTAIN web-based self-management mobile app, strengthening the patient–physician relationship and reinforcing the use of relevant clinical practice guidelines to guide management and prescribing. The primary outcome is the mean change in patient activation score using the Patient Activation Measure short form Malay version (PAM-13-M) questionnaire. The secondary outcomes include the changes in waist circumference, body mass index, blood pressure, patient physical activity level, eating behaviour, perception of chronic illness care, satisfaction with patient–physician interaction, and perceived absolute 10-year cardiovascular disease risk. Feasibility of implementing the intervention will be evaluated. This includes acceptability of the intervention, estimating the likely rate of participant recruitment and retention, appropriateness of the outcome measures, calculation of sample size, and the intervention’s potential effectiveness. CONCLUSION: To our knowledge, this is the first study in Malaysia that aims to determine the feasibility of a multifaceted e-health intervention, as well as to indicate more useful aspects of this intervention for further exploration in a larger trial. TRIAL REGISTRATION: ClinicalTrials.gov, NCT04120779. Registered on 9 October 2019, protocol version 1.


Contents of volume 301 (2005)


adr-type hepatitis B virus surface antigen for vaccine production obtained by culture of human hepatoma cell strain huGK-14


New dengue virus Type-1 strain; recombinant DEN1 protein expression; potential in recombinant vaccine construction, virus detection and dengue fever diagnosis and therapy


Recombinant DNA encoding hepatitis B virus polypeptide antigen is used in detection of infection and in vaccine production; production in prokaryotic or eukaryotic host; core antigen, surface antigen DNA sequence


Genetically engineered vaccines for mycobacterial antigens comprising recombinant poxvirus, e.g. vaccinia virus, capable of expressing Mycobacterium leprae, Mycobacterium tuberculosis or Mycobacterium bovis antigens


Bordetella bronchiseptica vaccine production by fermentation under specified conditions


What has Changed in Community-Acquired Pneumonia in Recent Years?


Issue TOC


JINF – Posters


Cumulative subject index volumes 168–173


Ribavirine : au revoir VHC, bonjour VHE


Subject index: Volume 32, 1999


Enteric viruses in a cohort of rural costa rican children()


Pathology of the Fischer Rat — Reference and Atlas


Isolated specific epitope region of thyroid peroxidase; for use as a recombinant vaccine in thyroid tumour or Hashimoto disease immunotherapy


Subject index for volume 190


Cumulative subject index volumes 69–75


Lead level in edible macromycetes in NW spain as biomarker in ecotoxicology


Esophageal function after cardiomyotomy for achalasia in children: A. Koch, M. Bettex, H. Tschäppeler, et al. Z Kinderchir 38:206–210, (August), 1983


Canine parvovirus vaccine preparation by growth of CPV-HP stem on dog tumour fibroblasts or renal cells


Pharyngitis: When is aggressive treatment warranted?: Bonilla JA, Bluestone CD. Postgrad Med 97:61, 1995


Feedback


Vulnerability to Poverty in South-East Asia: Drivers, Measurement, Responses, and Policy Issues


Vaccine against feline infectious peritonitis virus is prepared from virus FIPV 79-1146 serially passaged in non-oncogenic cell until nonvirulent


Subject Index of Papers Published in Volume 60 of the Journal of the American Dairy Science Association


Author index volume 85 (1989)


Allergie respiratoire


Vaccine against Schistosoma mansoni containing soluble antigen from larvae or adults


Pulsed low-energy infrared laser irradiation of human dentin, a SEM study


Infections respiratoires basses de l'adulte: pneumonie communautaire et bronchite aiguë


Feline T-cell lymphotropic lentivirus proteins; cat FIV virus used for the specific detection of FIV antibodies, production of antibodies and in vaccine; DNA sequence


Acute and chronic sinusitis: Ferguson BJ. Postgrad Med 97:45, 1995


Cumulative Index 1981, 1982, and 1983 Index


Information for authors


New DNA sequences of Epstein-Barr virus genome useful in protein expression for viral antibody detection in blood serum, for vaccine production and as DNA probe


60 Seconds


Subject index for volume 77


Antitumour vaccine containing major histocompatibility complex protein for metastase control; application in cancer therapy


Transmissible gastroenteritis (TGE): prophilactice with live homo- and heterovaccines


Environmental contaminations and immunosupression


Subject index for volume 174


Subject index for volume 112


title: Binge watching isn't as bad as we thought

text: It has been said that streaming 30 minutes of Netflix releases as much carbon as a short car ride, but this isn't true, says Michael Le Page


Detection of rotavirus and “corona-like virus” in stool samples of infected pigs by solid phase immune electron microscopy (spiem). Comparison of spiem with direct electron microscopy and enzymelinked immunosorbent assay (elisa)


Age and susceptibility to toxic substances: Calabrese, E. J. New York: John Wiley (1900)


Borrelia burgdorferi gene encoding conserved 79 kDa antigen: DNA probe or DNA primer and polymerase chain reaction for Lyme disease diagnosis and recombinant vaccine; monoclonal antibody production


Cumulative subject index volumes 174–179


Herpes virus recombinant pox virus recombinant vaccine; recombinant vaccinia virus, canary-pox virus, fowl-pox virus construction by insertion of glycoprotein gene from foreign herpes virus, pseudorabies virus, Epstein-Barr virus or cytomegalovirus


New protein comprising at least one hepatitis A virus epitope; capsid protein expression in vaccinia virus vector for use as recombinant vaccine


Preparation of a helicase region coded by hepatitis C virus; hepatitis C virus recombinant helicase production via gene cloning and expression in Spodoptera frugiperda insect cell culture using baculovirus vector : Soyaku Eng. Res. Inst. Jpn 06319 583; 22 November 1994


Contents List


Production of polypeptide for vaccine against malaria by cultivation of Escherichia coli transformed with vector coding for repeat unit circumsporozoite protein of Plasmodium falciparum


Vaccine against varicella-zoster virus (causative agent of chicken pox) using a DNA segment encoding the protective immunogenic gB glycoproteins


Cumulative subject index volumes 76–83


SARS, Greater China, and the Pathologies of Globalization and Transition


Contents index


Molecular biology of microbial pathogenicity: Adhesion, invasion and receptors: 17–20 June 1985 Umeå, Sweden organised by: S. Normark, B.E. Uhlin and H. Wolf-Watz on behalf of the Swedish Society for Microbiology and the University of Umeå


Cumulative subject index volumes 162–167


Author index to volumes 296–307 (2005)


Necrotising enterocolitis in small bowel atresia: K. Lafferty, R. J. Brereton, and V. M. Wright Z Kinderchir 38:224–227, (August), 1983


Next month's highlights


title: The legacy of BSE

text: We have to remain vigilant so we can act at the first sign of an emerging disease


Eimeria acervulina antigen isolation and use as a vaccine against fowl coccidiosis (US Equivalent)


Genetic reassortment of rotaviruses for production of vaccines and vaccine precursors


EM diagnostic determination of faecal viruses: Comparison of the direct staining method and the ultracentrifugation concentration method


Oral vaccine production by inactivating virus in the presence of protective compounds from the culture medium, adding further stabilizer and then freeze-drying


title: Deadly MERS virus could hold the key to its own cure

text: Recreating a small part of the MERS virus, which has killed 76 people so far, could block it from infecting cells and spreading disease


Malaria vaccine peptide Plasmodium falciparum circumsporozoite protein gene cloning in vaccinia virus


Patent report


Vaccine for immunizing cattle against lungworm comprising live immunogenic attenuated Dictyocaulus viviparus third stage larvae


Production of a vaccine against rotavirus disease; live attenuated strain containing the fourth rotavirus gene associated with attenuation


Antigen specific to non-A, non-B hepatitis virus: application for vaccine production


Vaccine comprising anti-idiotype antibody conjugate; induces production of neutralizing antibody (human monoclonal antibody, chimeric antibody or FAb, F(Ab′) 2 or Fv fragment) against HIV virus-1


index mots clés 2004


Gastric manometric abnormalities in patients with dyspeptic symptoms after fundoplication: V. Stanghellini and J. R. Malagelada. Gut 24:790–797, (September), 1983


title: Update on antimicrobial resistance: mechanisms, methods and practice

text: Antimicrobial resistance is a major problem for hospitals and the community. This interactive session developed for trainees will explore current antimicrobial resistance issues pertinent to the laboratory, including detection and importance in determining mechanisms of resistance, screening, therapeutic implications and consequences for infection control. Four trainees will present illustrative cases of antimicrobial resistance (MRSA, VRE, multi-resistant Gram-negative organisms and Candida) followed by expert panel discussion. Dr John Merlino will deliver an update on hot topics in antimicrobial susceptibility testing and resistance in a ‘show and tell session’. Finally trainees and the expert panel will have an opportunity to discuss prepared questions on antimicrobial resistance issues.


Subject index volumes 126–135 1990


New glutathione-S-transferase of Schistosoma mansoni; DNA sequence; site-directed mutagenesis and expression in Escherichia coli for use as recombinant vaccine or in therapy of schistosomiasis


Subject index for volume 176


Index des matieres 1980


New human recombinant cytomegalo virus containing foreign gene: DNA sequence encoding HIV virus antisense mRNA or malarial surface antigen


Keyword index to volumes 296–307 (2005)


title: B-02 Efficacité en situation réelle de la stratégie thérapeutique initiale dans l’exacerbation aiguë de la bronchite chronique (EABC) en France

text: INTRODUCTION ET OBJECTIFS: Évaluer l’efficacité de la stratégie thérapeutique dans la prise en charge de l’EABC en pratique courante. MATÉRIELS ET MÉTHODES: Cohorte prospective observationnelle auprès d’un échantillon aléatoire de médecins généralistes (MG) et pneumologues libéraux. L’efficacité était évaluée par le % de patients sans nouvelle consultation pour EABC à 3 mois. Le modèle de Cox a été utilisé pour la recherche de facteurs pronostiques. RÉSULTATS: 951 mg et 89 pneumologues ont inclus 4 994 patients. L’âge moyen était de 64,4 ans, avec 61,4 % d’hommes, 38,7 % d’anciens fumeurs, 35,7 % de fumeurs actuels. 2 ou 3 critères d’Anthonisen dont une expectoration muco-purulente étaient retrouvés chez 71,8 % des patients, 2 ou 3 critères hors expectoration mucopurulente chez 12,8 % et < 2 critères chez 15,4 %. Prescriptions : antibiothérapie (AB) à 91,9 % des patients, corticoïdes systémiques (41,5 %), mucolytiques (41,0 %) et bronchodilatateurs beta2-adrénergiques (30,7 %). L’absence d’une nouvelle consultation pour EABC à 3 mois concerne 63,8 % des patients. L’AB réduit le risque de survenue d’une nouvelle consultation (RR [IC 95 %] = 0,35 [0,13 ; 0,94]) chez les fumeurs actuels ayant au moins 2 critères dont une expectoration mucopurulente. Une corticothérapie systémique augmente le risque chez les patients ayant au moins 2 critères d’Anthonisen dont l’expectoration muco-purulente (1,16 [1,03 ; 1,30]) et chez les patients ayant deux critères d’Anthonisen hors expectoration muco-purulente ou moins de 2 critères (1,29 [1,06 ; 1,57]). CONCLUSION: Chez les fumeurs actuels ayant au moins deux critères d’Anthonisen dont l’expectoration muco-purulente, l’AB réduit de 65 % le risque de nouvelle consultation. La corticothérapie par voie générale augmente ce risque de 16 % à 29 % selon le groupe de patients.


Sonographic diagnosis of intussusception in childhood: E. Dinkel, M. Dittrich, G. Pistor, et al. Z Kinderchir 38:220–223, (August), 1983


Subject index for volume 182()


Preparation of cholera toxin subunit-B for use in vaccine preparation


VIRO-01 - Intérêt du test de diagnostic des virus respiratoires par PCR multiplex.


Chinese illness caused by a virus


Nematode protein complex; Haemonchus contortus immunogen and anthelmintic agent; protein sequence; recombinant vaccine production


Peptide capable of binding rubella immunoglobulin useful for rubella diagnosis and vaccine production; expression in Escherichia coli


Monoclonal antibody recognizing nucleic acid bases — useful for DNA sequencing, e.g. vaccine quality control


Oral vaccine for prophylaxis of periodontitis using the whole cell pilus or extract of Bacterioides gingivalis etc.


Antigen composition comprising PEB1 and/or PEB3 antigen from Campylobacter jejuni; useful as vaccine and for diagnosis of C. jejuni and Campylobacter coli infections


Orifice of ampulla of vater in duodenal web: M. Suga, K. Morita, I. Okabe, et al. J Jap Soc Pediatr Surg 19:919–923, (August), 1983


Combined enzyme-histochemistry and X-ray microanalysis on iron-containing organelles in hepatocytes of patients with hemosiderosis


Vaccine for preventing or treating T-cell mediated pathology; comprises an effective amount of a T-lymphocyte receptor and a pharmaceutical medium; application in rheumatoid arthritis, multiple sclerosis therapy, diagnosis, prevention


Cumulative subject index volumes 186–191


Graphical abstracts


Effect of atrazine on glucocorticoid receptor binding in rat


Recombinant pox virus expressing pseudorabies virus antigens used as live vaccines, for producing subunit vaccine and for diagnosis


Volume 22 Subject Index


Cumulative subject index volumes 148–155()


Envelope region nucleic acid fragment of type-C hepatitis virus and its detection; diagnosis using hepatitic C virus DNA probe or RNA probe; DNA sequence; potential recombinant vaccine preparation


Synthesis of dimeric Lex or difucosyl Y2 cancer antigen; useful as antitumor vaccine and to subside inflammatory processes of rheumatoid arthritis; preparation using α 1–3-fucosyltransferase


Involvement of (Na(+) + K(+))-ATPase in binding and actions of palytoxin on human erythrocytes: Böttinger, H., Béress, L. and Habermann, E. (Buchheim-Institut Für Pharmakologie, Justus-Liebig-Universität Giessen, Frankfurter Strasse 107, D-6300 Giessen, F.R.G.) Biochim. biophys. Acta861, 165–176. (1986).


Subject index for volume 188


Subject index for volume 165


New avirulent Salmonella-Escherichia coli hybrid strains useful in live oral vaccine against enteric diseases including cholera


Subject index for volume 116


Interpretive Summaries, March 2020


Cumulative subject index


Gene encoding H-protein of sclerosing-panencephalitis virus, a potential vaccine


Feline infectious-peritonitis virus vaccine; produced by serial passage in non-oncogenic e.g. FCWF, CrFK cell culture


Subject index for volume 128


Subject index*()


Subject index for volume 175


Vaccine comprising live attenuated or inactivated rotavirus strains; HRV 89-12C2, HRV 408, HRV 248 HRV 456 and/or CJN, for immunization against rotavirus illnesses


Appendixes


Emerging viral illnesses – preparedness, testing and assuring safety


Vaccine against transmissible-gastroenteritis virus of pigs; antigen from non-pathogenic pig respiratory-corona virus


Peptide fragments immunoreactive with HTLV-III virus (HIV virus) antibody obtained by expressing cloned fragmented HTLV-II provirus nucleotide sequences; vaccine production etc.


title: The past and present of malaria diagnosis

text: Within 30 years of Laveran’s discovery of human malaria parasites in 1880, four species, Plasmodium falciparum, P. vivax, P. malar-iae and P. ovale, had been described and their morphological distinguishing features clarified. Although other diagnostic techniques have been developed, 130 years later the gold standard is still examination of thick and thin blood films. Recently a fifth species, the monkey malaria Plasmodium knowlesi, has been found to infect humans in parts of Southeast Asia. With human activities continuing to impinge on the habitats of other primates, it is possible that other malaria species may cross over to humans as well.


Reduction rhinoplasty and nasal patency: Change in the cross-sectional area of the nose evaluated by acoustic rhinometry: Grymer LF. Laryngoscope 105:429, 1995


Enhanced quinone-induced oxidative stress in erythrocytes of thalassemic patients


Canine corona virus vaccine production by infected cell culture; effective against dog corona virus and dog parvo virus infection


Feline T-lymphotropic lentivirus (FTLV); separated from cell culture and useful as vaccine; hybridoma construction and monoclonal antibody preparation for use in immunoassay; DNA probe construction; and HIV virus model system


Subject index for volume 114()


title: Cytotoxic activity in culture filtrates from the entomopathogenic fungus Beauveria sulfurescens

text: The hyphomycete fungus Beauveria sulfurescens secretes into the culture medium several components toxic for Galleria mellonella larvae. Concentrated and dialyzed (cutoff 12,000) B. sulfurescens culture filtrate also contains a highmolecular-weight compound cytotoxic for the Mamestra brassicae cell line. A fractionation in two chromatographic steps separated a cytotoxic fraction (IC(50)= 1.15 ± 0.05 μg/ ml), which was poorly toxic to larvae (LC(50) = 150 ± 10 μg/ ml) and an insecticidal fraction (LC(50) = 2.1 ± 0.1 μg/ml) devoid of detectable cytotoxicity. The two kinds of activity, i.e., cytotoxicity in vitroand toxicity in vivo are thus independent. The cytotoxic activity, initially detected on a M. brassicae cell line, also affected two other insect cell lines (G. mellonella and Spodoptera frugiperda). The cytotoxic fraction provoked not only the inhibition of cell proliferation, but also cell death. Adhesive mammalian cell lines were not sensitive. Nonadhesive mammalian cell lines of murine myeloma and hybridomas were poorly sensitive.


Identification of a pro-inhibitory region on the surface of human CYP1A2


Antiviral Therapy: Respiratory Infections, Genital Herpes, and Herpetic Keratitis


Advances in Penicillium and Aspergillus systematics: Samson, R. A. and Pitt, J. I. (Eds) Proceedings of the First International Penicillium and Aspergillus Workshop, 6 – 10 May 1985, Amsterdam (NATO Advanced Science Institute - ASI - Series, Series A: Life Sciences, Vol. 102), X + 483 pp. ISBN 0-306-42222-0. New York: Plenum Press. (1985)


Peptides from merozoite stage of malaria parasite and DNA sequence encoding them; Plasmodium falciparum merozoite thrombospondin-related anonymous protein expression in Spodoptera frugiperda insect cell transformed with nuclear-polyhedrosis virus vector; vaccine


Aspects infectieux de la diarrhée aiguë de l'enfant en France : Pourquoi ce sujet en 1991 ?()


Inactivated canine coronavirus vaccine


Subject index for volume 186


Authors response to Influence of country of study on student responsiveness to the H1N1 pandemic


Ringworm vaccine; containing antigen from e.g. Microsporum canis, Microsporum gypsum or Trichophyton mentagrophytes


Keywords index


title: Working hypothesis

text: Sorting the week's supernovae from the absolute zeros


New epitope-bearing portions of Entamoeba histolytica; recombinant non-glycosylated epitope production and expression in prokaryote host cell, for application in a recombinant vaccine : Univ. Virginia Pat. Found. World 9500 849; 5 January 1995


Subject index for volume 166


Hepatitis C virus asialoglycoprotein-E1 and -E2; useful as vaccine or for diagnosis of non-A non-B hepatitis virus infection, or for concentrating or reducing HCV proteins in biological samples, and obtained by gene expression in yeast


January highlights


Recombinant feline corona virus-S protein; expressed as galactokinase fusion protein and useful as reconbinant vaccine, therapeutic and diagnostic agents for feline-infectious-peritonitis virus


Mucocele of the pteryomaxillary space: Stack BC, Klotch DW. Ann Otol Rhinol Laryngol 104:246, 1995


Un cinquantenaire : La mort de charles nicolle et le “destin des maladies infectieuses”


Recombinant pox virus containing Morbilli virus DNA; expression of e.g. measles virus haemagglutinin glycoprotein in host for construction of a potential recombinant vaccine against dog distemper virus


Recombinant Pseudomonas exotoxin produced by cloning of Pseudomonas aeruginosa DNA in Escherichia coli having low toxicity to human or mice cells but retaining enzymatic activity giving cell-specific immunotoxin; vaccine application


Mengo virus as a vector for expression of foreign polypeptides; hepatitis A virus, HIV virus, rabies virus, foot-and-mouth-disease virus, coronat virus, Rous sarcoma virus, herpes virus, etc., live attenuated recombinant vaccine : Inst. Pasteur Paris World 9429 472; 22 December 1994


Complex virus promoter; complex pox virus promoter construct; recombinant vaccinia virus construction


title: Threatwatch: Is the MERS virus spreading its wings?

text: The Philippines and Malaysia have identified their first ever MERS cases, while infections in Saudi Arabia surge, particularly among health workers


Contents of volume 296 (2005)


Intestinal protection against challenge with transmissible gastroenteritis virus of pigs immune after infection with the porcine respiratory coronavirus


Necrotizing enterocolitis in full-term newborns: E. de Gamarra, P. Helardot, G. Moriette, et al. Biol Neonate 44:185–192, (September), 1983


Synthetic peptide antigen corresponding to the major sites of T-lymphocyte recognition within the HIV virus envelope protein: recombinant vaccine production


Assuring result quality: Emerging and biosecurity nicrobiological agents


New gene fragment encoding rabies virus glycoprotein; DNA sequence expression in eukaryote cell culture and application to recombinant vaccine construction


index mots clés


Studies on immune responses and interference of oral polio vaccine (OPV) on seroconversion to rotavirus vaccine


Erratum to “Epitope mapping and biological function analysis of antibodies produced by immunization of mice with an inactivated Chinese isolate of severe acute respiratory syndrome-associated coronavirus (SARS-CoV)” [Virology 334 (2005) 134–143]


Vient de paraître


309 Quantitative tests (QLFTS) detect impaired hepatic function in a high proportion of chronic hepatitis C patients with fibrosis or compensated cirrhosis and may predict risk of cirrhosis, splenomegally, and varices


Subject index for volume 177


Vaccine for swine trichinosis comprising inert newborn Trichinella spiralis newborn larvae emulsified with an adjuvant


Molecular organization of positive-strand RNA viruses: 24–26 June, 1985 Cambridge, England organised by: D.J. Rowlands (Wellcome Biotechnology Ltd.), M.A. Mayo (Scottish Crop Research Institute) and B.W.J. Mahy (Animal Virus Research Institute) on behalf of the Virus Group of the Society for General Microbiology


title: An attempt at measuring health in nucleus and multiplier pig farms

text: A pilot epidemiological inquiry was undertaken in France in a group of 205 nucleus and multiplier pig farms. The aim was to find out a method for a quantitative evaluation of the health level in farms selling young breeders. An exhaustive protocol was prepared for data collection. The sources of information were clinical inspections on the farms, meat inspection data at slaughter and laboratory investigations. Data processing issued in the selection of a profile made of 14 prevailing health indicators. These were then associated so as to set up a health index with an overall score. In a second phase, the relevance of the method with respect to disease transmission was assessed. The principle was a contact challenge within totally controlled facilities between SPF pigs hysterectomy-derived and gilts taken from farms with different health scores as previously checked. The contact lasted for 28 days. Eleven farms were chosen and in every one of them 7 gilts were sampled and 10 SPF pigs were assigned to each of these farms. All the pigs were submitted to a detailed observation. At the end of it the pigs were euthanized at the laboratory and checked to find out any lesions and infectious agents. A wide range of symptoms appeared among the SPF pigs. Mortality rate was 14.6%. Pneumonia affected 23.7% of them. A relationship was found between the germ transfer and the severity of the troubles. The degree of illness in SPF pigs was clearly related to the score obtained previously in the corresponding farms. Consequently, the method was considered as valid with respect to health evaluation.


Subject index for volume 151


Methods in Cartilage Research


2007 Subject index


Que reste-t-il de la pathologie liée au VIH ?


Vaccine containing cattle papilloma virus-2 and/or cattle papilloma virus-4 L2 protein; for use as recombinant vaccine or in tumour therapy


Subject index for volume 130


Serial killers


Volume 63 - 2007


Volume 23 (2005) Subject Index


title: Natural infection with bovine virus diarrhoea virus in a dairy herd: A spectrum of symptoms including early reproductive failure and retained placenta

text: The consequences of natural infections by bovine virus diarrhoea virus (BVDV) in a dairy herd comprising approximately 60 cows were studied over a 3 year period. The outcome of 39 pregnancies after artificial insemination or natural service during a 4 month period of risk for contracting BVDV was nine abortions, one mummified foetus, one still-birth, three calves that died within 1 week of age, 12 calves persistently infected (PI) with BVDV (11 males and one female) and 13 non-PI calves. Retrospective studies showed that only two of the 13 dams (15.4%) of non-PI calves had been inseminated once, which is a significantly (P < 0.001) lower rate than for 192 other gestations (66.7%) during the 3 year period. The gestational duration of multiparous cows (but not of heifers) was longer (P < 0.01) for five cows with PI calves (mean ± SD 287.6 ± 9.5 days) than for 53 other gestations in 35 cows (280.6 ± 3.8 days). Five of the 12 dams of the PI calves had not expelled the foetal membranes within 2 days after calving, which is a higher (P < 0.001) incidence than the seven cases of retained placenta observed after 198 other calvings. Furthermore, there was a 4.4-fold higher risk (P < 0.01) of treatment for enteritis and/or pneumonia in calves and a 6.0-fold higher risk of calf mortality associated with the introduction of BVDV. The mean heart girth of the PI calves was less (P < 0.05) than that of non-PI calves, at both 80 and 180 days of age.


Controverse : pour ou contre la PCR multiplexe dans les infections respiratoires


Pathogen strain Borrelia burgdorferi ZS7 (DSM 5527); for the production of passive antibodies for the treatment of Lyme disease : Max Planck Soc; German Cancer Res. Inst. Eur 633 313; 11 January 1995


AIDS recombinant vaccine; recombinant HIV virus core protein cloning in vaccinia virus vector


Subject index for volume 180


Inactivated poultry plague vaccine from virus Newcastle disease culture in incubated hen egg


Severity of rotavirus infection in relation to serotype, monotype and electropherotype


Parallel sessions


Pilgrims warned of MERS


Inactivated pigeon herpes virus vaccine from chicken fibroblast cell culture


New vaccine against infectious viruses — e.g. feline infectious-peritonitis virus, providing cell-mediated immunity


Interpretive Summaries, April 2010


Cumulative subject index volumes 92–99()


Diphtheria recombinant vaccine; comprises Corynebacterium diphtheriae toxin-A fragment mutein, Gly158 DT-A, which is enzymatically inactive; DNA sequence


Protecting against Bordetella pertussis or Bordetella bronchiseptica using native, recombinant vaccine consisting of 69 kDa outer membrane protein or filamentous hemagglutinin protein purified from B. pertussis, Bordetella parapertussis or B. bronchiseptica


New recombinant adenovirus used as vaccine; dog adenovirus-2 vector; dog parvovirus, cat panleukopenia virus, cat or dog coronavirus, dog distemper virus, cat leukemia virus, rabies virus or FIV virus recombinant vaccine construction


Influenza virus inactivated vaccine for pig: virus culture in embryonated egg allantoin and preparation


Medical progress: recent progress in poliomyelitis research


Keyword index to volumes 284-295 (2004)


Cumulative subject index volumes 180–185


Deactivated triple vaccine for abortus fever, Ibaraki disease and Akabane disease produced by incubation of the viruses in cell culture


Subject index for volume 78()


Protein homologous to Trypanosoma cruzi heat shock protein; used in vaccine and diagnosis of e.g. Mycoplasma or Mycobacterium


I16 Hemophilia


Total volvulus with complete necrosis of the small bowel and pseudocystic tumor: K. J. Neis and H. Seeliger Z Kinderchir 38:249–252, (August), 1983


Cumulative subject index volumes 156–161


Pertussis: 22–24 April 1985 Potsdam, GDR. Postponed


Parasitic nematode vaccine for human and animal protection fusion protein expression


title: Advances in Nutrition and Management of Calves and Heifers

text: Strides have been significant in the knowledge of calf and heifer rearing during the last 25 yr. Much information has been gathered on digestive enzymes, development of the digestive system, and metabolism. Investigations have clarified further the role of colostrum in immunity and nutrition of the young calf. Several sources of nutrients have been tested for their suitability in formulation of acceptable milk replacers and calf starters. Once-a-day feeding of milk, colostrum, or milk replacer and early weaning are practical management procedures. Labor and cost efficient methods of feeding and caring for young calves have developed. Extensive work on rearing rates and methods of rearing was published during these 25 yr. Successful schemes have evolved for feeding heifers to freshen at an optimal age and to occupy a respectful position in the milking line. Developments in housing have been phenomenal – from the calf hutch to environmentally controlled nurseries for calves. Heifer housing has ranged from relatively simple, but labor-efficient housing, to complete confinement systems. Herd health programs have developed to minimize many disease problems that can be particularly disastrous in large herds. Contract rearing of herd replacements has become a more frequently chosen option in this period. Budgets for rearing calves from birth to freshening have appeared in recommendations for raising heifers.


INF-04 Nouvelles Infections : Gestion Pratique D'Une Épidémie Dans Un Service D'Infectiologie


Polypeptide derived from Plasmodium falciparum antigen GLURP; vector plasmid pRD15 expression in Escherichia coli or Bacillus subtilis; recombinant vaccine construction and malaria therapy; monoclonal antibody and hybridoma preparation


title: Wuhan virus spreads

text: We now know the virus responsible for deaths and infections in China can pass between people, reports Jessica Hamzelou


Canine coronavirus vaccine


New nucleic acid encoding E2 protein of canine corona virus; dog corona virus recombinant E2 protein production; may be used in recombinant vaccine production


Plasmodium Duffy receptor protein; Plasmodium knowlesi or Plasmodium vivax gene cloning and expression; potential recombinant vaccine against malaria; DNA sequence


Generic names of viruses of vertebrates


Author index()


Volume 59 of the Journal by the American Dairy Science Association


Multivalent pneumococcal vaccine and its preparation from polysaccharide purified from Pneumococcus


Candida guilliermondii immunobiological composition production by aerobic cultivation of the organism and extraction, used for diagnosis prophylaxis and treatment of infections, and as vaccine


Heterologous virus peptide immunogen production: recombinant vaccine production in L-cell, Chinese hamster ovary, C127 cell culture


Bioterrorism: introduction


Nucleic acid encoding a T4 glycoprotein used for treatment of AIDS and producing antibodies for use as a vaccine for immunization against AIDS


Superoxide dismutase and catalase in ethanol treated rats


Strain-independent inactivated influenza vaccine production by removal of the hemagglutinin heavy HA1 chain


PhoE protein with an inserted antigenic determinant — at a region localized at Enterobacteriaceae cell surface for production of vaccine and diagnosis purposes


Live or inactivated canine coronavirus vaccine; new antigen dog coronavirus isolate


title: Prevention of Common Colds by Hydrotherapy: A Controlled Long-term Prospective Study

text: In a search for an effective prophylaxis against common colds, 25 volunteers were treated regularly with a standardised hydrotherapy programme for half a year, while 25 matched untreated persons served as controls. The frequency, duration and strength of colds were recorded. Results show that there is a significant reduction in frequency of colds in the treated group. Similarly, this group seemed also to be affected less severely. The duration of common colds was shorter in the treated group which, however, failed to reach the level of significance. The prophylactic effects took about three months to become apparent. The underlying mechanism, by which the effect is mediated, is speculative at present. It is suggested that regular hydrotherapy represents an effective prophylaxis against common colds.


New canine parvo virus strain 154 and use in vaccine effective in young animals in the presence of maternal antibodies


Subject index for volume 183()


Nucleic acid constructs, malaria polypeptides and vaccines; recombinant malaria serine-repeat antigen production in yeast for the construction of a recombinant vaccine


title: B-01 Évaluation des Pratiques Professionnelles (EPP) et Tableau de Bord (TB) : exemple du Traitement des Pneumonies Aigues Communautaires (PAC)

text: INTRODUCTION ET OBJECTIFS: L’EPP vise à améliorer nos pratiques médicales. Elle comporte 3 phases : la mise en évidence de dysfonctionnements, la proposition de mesures correctives puis l’évaluation des ajustements induits. L’EPP est difficile sans outil pertinent. Notre objectif est d’illustrer l’intérêt d’un TB pour réaliser une EPP. MATÉRIELS ET MÉTHODES: Notre TB existe depuis Juillet 2005, incluant 24 paramètres dont le diagnostic, l’antibiothérapie et la date d’hospitalisation. Lors de la 1(re) phase d’EPP, le TB a été utilisé pour étudier les modalités thérapeutiques des PAC, révélant une hétérogénéité d’antibiothérapie non justifiée (Med Mal Inf 2008;9:457-64). La 2(e) phase a consisté en l’écriture de notre protocole thérapeutique, visant à réduire les prescriptions de fluoroquinolones (FQ) et de céphalosporines de 3(e) génération (C3G). Nous rapportons ici la 3(e) phase d’EPP, utilisant le TB pour comparer l’application du protocole sur 2 périodes : avant (d’octobre à janvier 2005 et 2006) et après (d’octobre 2008 au 20 février 2009) sa mise en place. L’utilisation de plusieurs lignes thérapeutiques, suggérant l’inadéquation de l’antibiothérapie initiale, a été répertoriée. RÉSULTATS: Les PAC représentaient 178 hospitalisations avant l’application du protocole, et 81 après. Le taux de conformité avec le protocole était respectivement de 101/178 (57 %), et de 52/81 (64 %). Le nombre d’antibiothérapies contenant des FQ et/ou des C3G de manière inadéquate était de 45/178 (25 %) durant la première période, et de 19/81 (23 %) durant la seconde période. Plusieurs lignes thérapeutiques étaient utilisées 28/178 fois (16 %) et 12/81 fois (15 %). La durée d’hospitalisation était respectivement de 9 ± 5 et 8 ± 5 jours, une évolution défavorable étant observée dans 8/178 (5 %) et 1/81 cas (1,2 %). CONCLUSION: Un TB permet l’exécution rapide de 2 des 3 phases de l’EPP. Nos résultats suggèrent une appropriation partielle de notre protocole, la réduction des FQ et des C3G apparaissant sans impact sur la morbi-mortalité.


A trial of the immunogenicity of inactivated hepatitis A vaccine administered with immune serum globulin


title: Comparison of cytopathogenicity, immunofluorescence and In situ DNA hybridization as methods for the detection of adenoviruses

text: Three different methods were compared for their efficiency at detection of adenoviruses. The samples examined for viral analysis consisted of concentrates prepared from raw sewage, chosen as providing a representation of the spectrum of viruses being intestinally shed from a large population at any given time. When using one single cell line, HEp-2, the overall numbers of adenoviruses detected using cytopathogenicity and immunofluorescence were roughly equal. In situ hybridization was approx. 40% more sensitive than either of these other methods as determined by average virus titers for the different samples, and also proved to be better by means of a nonparametric comparison. The 293 cell line was approx. 5 times more sensitive for detecting adenoviruses by cytopathogenicity as compared with the HEp-2 cell line, but proved unsuitable in our hands for quantitatively detecting indigenous adenoviruses by immunofluorescence. The relative number of indigenous adenoviruses present in the sewage concentrates we examined was, on average, 94-fold greater than that of enteroviruses. Assay of enteroviruses was performed by plaque assay in the BGM cell line.


Bordetella pertussis coding sequences used for producing polypeptides that retain immunogenicity but lack virulence for vaccine production


Immunologically active parvovirus B19 peptide; comprises capsid protein VP1 or VP2 fragment; application to recombinant vaccine construction and disease diagnosis; protein sequence


Rhinopharyngite aiguë


Vaccine for use in cases of sheep foot-rot comprising at least one protease of Bacteroides nodosus


Non-infective structural particle preparation containing flavivirus surface antigen protein; Japanese-encephalitis virus cDNA gene cloning in dengue virus-2-preinfected cell with a vaccinia virus vector and use of a non-infective structural particle as recombinant vaccine


Subject index for volume 134


Universal coronavirus vaccine; spike protein cloning and expression for use as a recombinant vaccine


Index des mots clés


Subject index for volume 169


Cumulative subject index volumes 132–139()


Complications of viral and mycoplasmal infections in rodents to toxicology research and testing. Chemical Industry Institute of Toxicology Series: Hamm, T. E. London: Hemisphere. (1986)


Antigens of Cysticercus cellulosae; used for antibody production, treatment of neurocysticercosis, diagnosis or vaccine production


Síndrome respiratorio agudo severo en la UCI


Peptide blocking the binding of P. aeruginosa to buccal epithelial cells; Pseudomonas aeruginosa recombinant epitope peptide production for use as recombinant vaccine and as adjuvant in lung cancer therapy


Thème : Infections virales


Answer to Picture Quiz


Tourism in China: A. Lew, L. Yu, J. Ap and Z. Guangrui (Eds.); The Haworth Hospitality Press, New York, 2003, pp. 325, (softback), ISBN: 0789012820


Técnicas microbiológicas en el estudio de las infecciones pulmonares en el paciente con SIDA


Subject index for volume 108


title: One slip up from a worldwide pandemic

text: Do the risks of a lethal flu virus escaping the lab outweigh the benefits of the research, ask Peter Aldhous and Debora MacKenzie


Suppression of nonsense codon or frameshift mutation especially useful in vaccine production


Cumulative subject index for volumes 108–115


Novel strain of influenza virus is useful in inactivated vaccine production


Chronic intestinal pseudo-obstruction in children: W. Yanxia. Chin J Pediatr Surg 3:21–23, (March), 1982


New peptides with immunological properties of HIV-2 envelope protein with the structure of simian immune deficiency virus proteins, useful in dignosis and as vaccine components


Subject index for volume 110


cDNA clone of non-A non-B hepatitis virus (NANB) post transfusion and its use — DNA sequence; potential application as recombinant vaccine; DNA probe application in disease diagnosis


Endoscopic intranasal frontal sinusotomy: Har-El G, Lucente F. Laryngoscope 105:440, 1995


Subject index for volume 157


INF-01 Les Isolements : Actualites Et Perspectives


Transgenic plant expressing antigen of pathogenic organism; e.g. using Escherichia coli or Streptococcus mutans, used for oral immunization to inhibit colonization or invasion by pathogens


Cumulative Index: 1980, 1981, and 1982


Mitteilungen des Berufsverbandes der Deutschen Radiologen


Continuing Education and Meeting Calendar


Now, more than ever, our community is needed: spinal cord injury care during a global pandemic


What is acute gastro-enteritis in young children?


title: Why Can't We Just Use PCR? The Role of Genotypic versus Phenotypic Testing for Antimicrobial Resistance Testing

text: There is a need for phenotypic susceptibility testing that is expeditious and that can be performed directly from clinical specimens. While rapid pathogen identification is important, it is the susceptibility result that is essential for antimicrobial optimization. The options for rapid susceptibility testing are limited, with the majority of commercial tests available offering genotypic resistance detection only. In this article, a laboratorian and a clinician discuss the benefits and limitations of genotypic and phenotypic susceptibility testing and provide examples of how results should be interpreted to maximize the clinical utility.


On vous demande, sachez répondre


Coronavirus NL63 Illnesses in Infancy are a Risk Factor for Asthma at Age Six


Effect of farming environment on atopic diseases in mongolia()


Lung Features of Infection with Corona Virus in Wistar Rats


Effect Of Tobacco Smoke And Respiratory Virus Infection In Preschool-aged Children


Contents of volumes 263, 264, 266–289


Analysis of the complete genome sequences of human rhinovirus


Respiratory Virus Detection in Nasal Lavage Fluid of Chronic Rhinosinusitis Patients During Acute Exacerbations


Airway function during mild viral respiratory illnesses. The effect of rhinovirus infection in cigarette smokers: Fridy, W. W., Jr., Ingram, R. H., Jr. Heihdser, J. C., and Coleman, M. T.: Ann. Intern. Med. 80: 150, 1974


Scientific Abstract Sessions


Age-related maturation of the nasal immune system in children()


Viral Detection and Cytokine Profile in Early Transient Wheeze and Childhood Asthma


1. Decreased urinary cyclic 3′,5′-vdenosine manophosphate (CAMPY after epinephrine? in asthmatic patients


Does the immune response to cat among children living with a cat influence the prevalence of IgE to dog and birch?()


Viral Etiology and Rhinovirus Serotypes of Recurrent Respiratory Illnesses during Infancy


Viral infections in relation to age and the atopic status of children hospitalized for wheezing()


Author Index to Volume 67


The contributions of allergic sensitization and respiratory pathogens to asthma inception


Viral Detection and Rhinovirus Strain Identification among Asthmatic Children During Peak Times of Asthma Exacerbations


Allergy is a negative prognostic factor for the outcome after sinus surgery()


Paradoxical effect of cow dung exposure on childhood atopy in rural and urban children in South India()


The effect of frequent administration of sodium cromoglycate to asthmatic children who previously responded poorly: Konig, P., and Godfrey, S.: Clin. Allergy 3: 395, 1973


Validation of the classification of aria (Allergic rhinitis and its impact on asthma)()


Viral Infections and Their Impact on the Respiratory Microbiome in Pediatric Patients with Cystic Fibrosis


Asthma in the elderly: Diagnosis and management


Prevalence of Respiratory Viruses in Patients with Acute Respiratory Infections in Korea


Evaluation of an environmental exposure unit (EEU) for controlled inhalation studies with pollen allergens()


Exacerbation de l'asthme: le role declenchant des coronavirus humains n'est pas confirme


Lots in common


Evaluation de la technique d'utilisation de la chambre d'inhalation avec masque facial dans le traitement de l'asthme


Index to subjects


Insuffisance cardio-respiratoire reversible par hypoplasie de l'etage moyen de la face chez un enfant achondroplase


Graphical abstract TOC continued


Pneumopathie aigue bacterienne et infection vih chez l'enfant en milieu tropical


Graphical Abstract Contents Continued


Cumulative index of reviews for 1980–1985


Proteins: stay tuned!


Response from Lane and Buchmeier


title: The aquaporin family of membrane water channels

text: The rapid movement of water across the plasma membranes of certain cells has been a long-standing puzzle to membrane biophysicists and physiologists; the discovery of the red cell channel-forming integral protein has provided a molecular solution to this puzzle. The identification of this protein has led to the recognition of a family of related water-selective channels, the aquaporins, that are found in animals, plants and microbial organisms. In order to provide insight into the remarkable but simple function of these membrane proteins, their structures are being elucidated.


Membrane proteins


Deep life


Pyelonephrite aigue chez l'entant a propos de 79 cas


Diagnostic des infections respiratoires par amplification des acides nucléiques


Complications de la rougeole et facteurs de risque de deces


Current opinion in structural biology


Forthcoming articles page


Double dealing


Role pathogene des coronavirus humains chez l'enfant: analyse systematique de la litterature


Subject index for research articles and reviews, 1989


Tolerance d'infanrix polio-Hib en rappel chez 950 nourrissons


Des vaisseux et des gènes


Proteins — discovery and detail


Digénisme : le retour


title: RNA pseudoknots

text: Many new RNA pseudoknot structures have been detected and proposed in the past year. Although we are still waiting for the first detailed structure of a pseudoknot, their role in processes such as translational autoregulation or ribosomal frameshifting has been extensively studied and is now well established. Pseudoknot structures appear to play a pivotal role in small subunit ribosomal RNA and in the noncoding regions of viral RNAs. There are also strong indications that RNA pseudoknots are highly suitable structural motifs for the recognition and binding of proteins.


Contents and Editorial Board


Editorial Board and Contents


Index to volume 29


Sobre la necesidad de modernizar la vigilancia epidemiológica y de ampliar el uso del diagnóstico molecular para las enfermedades infecciosas en Colombia


Author indexes


title: New methodologies for the pathologic diagnosis of placental infections-immunohistochemistry, immunofluorescence, in situ nucleic acid hybridization and polymerase chain reaction: A review

text: A variety of highly sensitive laboratory techniques is now available for the detection and localization of infectious agents in the placenta. This communication discusses, the role of immunohistochemistry, immunofluorescence, in situ nucleic acid hybridization, and polymerase chain reaction for infectious disease diagnosis in formalinfixed placental tissues. These techniques, as well as other sophisticated molecular methods currently in development, will greatly facilitate characterizing the role of infectious agents in a variety of perinatal and pediatric conditions, including birth defects, intrauterine growth retardation, and stillbirth.


Patent Reports


Recent research in infectious disease


Contents of other veterinary journals from Elsivier


title: Gastroenteritis in Auckland: An aetiological and clinical study

text: Faecal specimens from 60 patients (under six years old), most of whom were Maoris and Pacific Islanders admitted to Auckland Hospital with gastroenteritis during the months of June and July 1977, were examined for the presence of faecal viruses, bacterial pathogens and parasites. Faecal specimens from 18 non-diarrhoeal control patients were also examined, of which three contained rotavirus. Forty-three (72 per cent) gastroenteritis patients had rotavirus detectable in stools by electron microscopy or immune electron microscopy. Of the remainder, 17 patients were regarded as having non-rotavirus diarrhoea. Enterotoxigenic Esch. coli. was isolated from seven patients of whom six yielded stable toxin producers (ST+), four labile toxin producers (LT+) and two dual toxigenic strains (ST+/LT+). All ST+ isolates appeared to be of low enterotoxigenicity as indicated by low gut weight/carcass weight ratios in the infant mouse assay. Rotavirus was the commonest aetiological agent (72 per cent), bacterial pathogens (alone) accounted for only five per cent and no enteric pathogens were found in 15 per cent of cases. Non-agglutinable rotavirus, presumably a different serotype, was seen in both gastroenteritis and control patients. Rotavirus ‘satellite’ particles previously undescribed were demonstrated in a number of stool samples.


Volume Contents Index


ISAR News


Contents of Veterinary Immunology and Immunopathology, Volume 112


Recent research in infectious disease()


Volume Contents, Author and Subject Index for Vol. 42


Author Index to Volume 31


Neonatal bacterial infection: A changing scene?


Antiviral activities of interferons


IFC - Editorial Board / Publication Info


Table of Contents from Journal of Psychosomatic Research


A comparative analysis of the porcine, murine, and human immune systems


title: Viruses demonstrated in children in Tanzania: Studies in diarrhoea and measles

text: Causes of diarrhoea with particular reference to viral agents were investigated in 123 infants and young children in Dar es Salaam, Tanzania. Twenty-six of the patients also had measles. Viruses were found in 52 of the 123 patients (43 per cent) and rotavirus occurred in 38 children (31 per cent). Enteroviruses were found in 10 patients, adenoviruses in nine and ‘small round virus’ in one (six patients had dual infection). Four patients died and only one of these children had viral particles in the stools. Breast milk formed part or all of the diet in 77 children (63 per cent) and virus isolation showed a similar pattern in breast fed infants and those not receiving breast milk. In 26 patients with measles only five were excreting viruses in their stools. Therefore no strong evidence was found to link the diarrhoea associated with measles in Tanzanian children to any particular virus. The pattern of virus infection causing infantile diarrhoea was similar in Dar es Salaam to other parts of the world.


SUBJECT INDEX


The Journal of Comparative Pathology Educational Trust and Petplan Charitable Trust Joint Research Award in Veterinary Pathology


Master subject index


Subject Index to Volume 65, issues 1 and 2


Ocular and central nervous system involvement in non-effusive form of feline infectious peritonitis


Related Elsevier virology titles contents alert


Contents of volume 39


Author index (vols. 2–3)


Cumulative Subject Index for 2005


Gene expression, virulence and vaccine development in coronaviruses


title: V, 2.Ribosomal frameshifting in astroviruses

text: This chapter reviews ribosomal frameshifting with an emphasis on the frameshifting process in astroviruses. Frameshifting is a potential antiviral target. It is possible that the replication cycle of any virus that uses this process could be disrupted by modulation of frameshift efficiencies, but a better understanding of the occurrence and the molecular basis of frameshifting will be required before it can be considered a genuine target. To date, there are no confirmed examples of frameshift signals from conventional eukaryotic cellular genes, although computer-assisted database searches have identified a number of candidates. The frameshift allows the required ratio of viral proteins to be produced, but it may also serve to downregulate levels of viral replicases that may be toxic in high amounts.


Development of a Cell-Based Assay for Identification of Viral Entry Inhibitors Against SARS-CoV by High Throughput Screening (HTS)


Subject index (volume 5)


Contents of volume 38


Contents of volume 3


4904391 Method and apparatus for removal of cells from bone marrow: Richard B Freeman


Viral etiology of multiple sclerosis: where does the truth lie?


title: I, 3. The enteric nervous system and infectious diarrhea

text: This chapter discusses the background knowledge about the enteric nervous system (ENS) as well as the role of ENS in secretory states of the small intestine. The chapter describes the anatomy and physiology of the ENS. A description of the experimental evidence for the involvement of ENS in secretory states of the gut, primarily in cholera toxin-induced secretion that is the most thoroughly investigated secretory state, is presented in the chapter. The chapter focuses on the involvement of ENS in rotavirus (RV) diarrhea. The involvement of the ENS in diarrhea pathophysiology opens up new potential sites of action for drugs in the treatment of intestinal secretory states. The chapter concludes with a discussion of the sites of action for the pharmacological treatment of diarrhea.


4904596 Hybridoma antibody (FH6) defining a human cancer-associated difucoganglioside: Sen-itiroh Hakomori assigned to Fred Hutchinson Cancer Research Center


4904481 Method of conferring immuno-tolerance to a specific antigen: C Garrison Fathman assigned to The Board of Trustess of Leland Stanford University


4902685 2-Amino-3-cyano-bicyclic pyridines/pyrazines as inhibitors of interleukin 1: Jerauld Skotnicki assigned to American Home Products Corporation


Evaluation of Interferon Inducers, Ribavirin and Mouse Hyperimmune Serum in a Pathogenesis/Lethal Mouse Model Using a Mouse-adapted SARS-CoV


Contents of volume 12


Effects of the Addition of Hiltonol(®) (Poly-ICLC) to a SARS-CoV S Protein Vaccine in Lethal SARS-CoV Mouse Model


19th ICAR Abstracts:


5420253 Method for purifying egg yolk immunoglobulins : Emery Daryll A; Straub Darren E Willmar, MN, United States Assigned to Willmar Poultry Company Inc


title: The role of pathogenic Escherichia coli in the etiology of veal calf hemorrhagic enteritis

text: Veal calf hemorrhagic enteritis, a condition that has no identified specific etiology, is a fatal syndrome of veal calves and has recently become a major concern of the veal calf industry in the midwestern United States. To determine the possible role of common enteric pathogens in this disease, 40 veal calves with hemorrhagic enteritis (cases) and 25 dairy calves diagnosed with enteric infection (control) were investigated. The veal calves were negative for several known enteric pathogens except for pathogenic Escherichia coli isolates that expressed multiple virulence attributes. To determine whether such isolates have a significant association with hemorrhagic enteritis in veal calves, we compared the prevalence of pathogenic E. coli in the 40 veal calves with the prevalence of similar E. coli in the dairy calves that were diagnosed with colibacillosis within the same season of the year. Escherichia coli isolates from the two groups of calves were tested for several properties of E. coli related to pathogenicity, i.e. production of verotoxins, heat-stable enterotoxin (ST(a)), heat-labile enterotoxin, enterohemolysin, K99 fimbrial antigens, hemagglutination activity, and attachment to Hep-2 tissue culture cells. Escherichia coli that produces ST(a) were more commonly isolated from veal calves with hemorrhagic enteritis (45%) than from dairy calves with enteritis (12%) (P<0.05). Various patterns of attachment of E. coli to Hep-2 tissue culture cells were studied. The E. coli that demonstrated aggregative patterns of attachment were more commonly represented in veal calves (32%) than in dairy calves (8%). We observed that there was no correlation between ST(a) production and K99 pili expression among the enterotoxigenic E. coli (ETEC) isolates that were recovered from veal calves. This may indicate the emergence of K99-negative ETEC, probably as a result of the wide use of K99-based vaccines.


Scientific program


title: Epidemiologic approaches used in a herd health practice to investigate neonatal calf mortality

text: Epidemiologic methods were applied in an investigation into causes of neonatal mortality on a 1400-cow dairy in the southern San Joaquin Valley of California. A format for collation of information on birthdate and date of death was assembled into a matrix which improved conceptualization of the data and which simplified procedures for estimation of mortality rates. Contemporary and birth cohort life table methods, mortality density estimations and relative risk assessment were used to ascertain if there were high-risk groups of calves that could be identified by age, day-of-the-week born, day-of-the-week died and sex. During the outbreak of neonatal diarrhea on this dairy, female calves were found to have experienced an atypically higher rate of mortality (10.7%) than did males (5.3%). Calves of both sexes died between the ages of 9 and 19 days. In addition, the risk of dying was 11 times greater for calves born on Wednesdays than for those born on Saturdays. These findings formed the basis for recommended changes in management of neonatal calves on the dairy.


P232 MOLECULAR PHYLOGENETICS OF HEPATITIS C VIRUS (HCV) AS A TOOL TO UNDERSTAND THE HCV EPIDEMIC IN BRITISH COLUMBIA (BC), CANADA


Author index of volume 178 Supplement 1


Cumulative Author Index for 2010


High Throughput Screening of Protease Inhibitor Libraries Using a Novel Dual Pseudotype-Based Assay for SARS-CoV Entry


P233 THE NATURAL COMPOUND PENTA-O-GALLOYL-GLUCOSE, DERIVED FROM THE ROOT CORTEX MOUTAN, EFFICIENTLY INHIBITS HEPATITIS C-VIRUS ENTRY AND SHOWS EXCELLENT PHARMACOKINETIC PERFORMANCE IN VIVO


5424065 Vaccines containing avirulent phop-type microorganisms : Curtiss Roy;Galan Jorge St Louis, MO, United States Assigned to Washington University


Contents of volume 71


Contents of volume 35


5013542 Method to inhibit adhesion of disease-causing microorganisms to teeth: Donald I Hay, Ronald J Gibbons, Edgard G Moreno assigned to Forsyth Dental Infirmary for Children


title: The prevalence of some economically important swine diseases in farrowing units in southwestern Finland

text: The prevalence and geographical distribution of some economically important swine diseases were surveyed in 114 randomly selected farrowing units which had a contract with Southwestern Finland's Cooperative Slaughterhouse (LSO) for producing feeder pigs to be delivered to the all in-all out finishing units. The focus was on infectious diseases which could be transmitted to the finishing units with delivered growers, and which might have some influence on partial carcass condemnations (PCC) in meat inspection. Farm visits were done by a veterinarian (senior author) assisted by a technician. Colostrum samples (average 22 per herd) were taken in 100 herds, and analyzed for Actinobacillus pleuropneumoniae (A. pleur) and Mycoplasma hyopneumoniae (M.hyo) antibodies by enzyme-linked immunosorbent assays (ELISAs). Only nine of 114 herds were judged to be free of mange. It was concluded that all finishing units received mange-infected feeder pigs each time the unit was filled. One or more acute erysipelas outbreaks had occurred in every fifth herd during the previous year. The risk of a finishing unit receiving feeder pigs carrying erysipelas was considered to be high. Swine dysentery (Serpulina hyodysenteriae) was not found to be a problem in the LSO area. Clostridium perfringens type C enteritis was found in eight (7%) herds. Seven of these herds were located in those supply areas where the PCC percentage of feeder pigs was high. In spite of statistical connection no causality between this disease and PCC was presumed. There were no previous diagnoses of respiratory diseases but spontaneous coughing was observed in 5% of the herds. Provocation testing induced coughing in 22% of herds but not serious coughing in any herd. Managers had observed coughing in 15% of herds. Ninety-one herds were positive in a colostrum ELISA for A. pleur antibodies, and eight herds were positive for M.hyo antibodies. A.pleur-positive herds had several positive or samples suspected of being positive in each herd bu M.hyo-positive herds had only one or two positive or suspected samples per herd. Six of the M.hyo herds were located in the high PCC area, two in the average PCC area and none in the low PCC area. M.hyo was suggested to be one of the possible explanations for geographical variation of PCC. Atrophic rhinitis was not considered to be of importance in LSO.


5017559 Agent for blocking nonspecific adsorption, process for preparing thereof and method of blocking nonspecific adsorption: Shunichi Dosako, Hiroshi Shinmoto, Saitamaken, Japan assigned to Snow Brand Milk Products Co Ltd


title: Detection of foot-and-mouth disease virus infection-associated antigen antibodies: comparison of the enzyme-linked immunosorbent assay and agar gel immunodiffusion tests

text: A liquid-phase enzyme-linked immunosorbent assay (ELISA) was compared with the standard agar gel immunodiffusion test (AGID) to identify and quantify antibodies against foot-and-mouth disease (FMD) virus infection-associated (VIA) antigen. A total of 3181 cattle sera were tested. Of these sera, 1885 were from cattle which had not been exposed to FMD. A total of 1296 sera were either from cattle which were experimentally exposed to FMD virus or from cattle involved in field outbreaks. The results indicate that the ELISA has the same specificity as the AGID test, but is more efficient in detecting cattle exposed to FMD virus. The ELISA technique will probably prove to be a more satisfactory test in support of the prevention, control and eradication programs for the disease.


P234 MYELOID-DERIVED SUPPRESSOR CELLS AND DENDRITIC CELLS FOR IMPAIRED RESPONSE TO VACCINE IN MICE WITH NONALCOHOLIC FATTY LIVER DISEASE


Identification of New Druggable Antiviral Targets by Chemical Genetics


Inhibition of Severe Acute Respiratory Syndrome Coronavirus Replication in a Lethal SARS-Cov Balb/C Mouse Model by Stinging Nettle Lectin, Urtica Dioica Agglutinin (UDA)


Potent Inhibition of Viral Entry and Replication of SARS-CoV by siRNAs Targeting the Genes Encoding the Cellular ACE2 Receptor or the Viral Nucleocapsid Protein


Contents of volume 20


Author index (vol. 15)


5419907 Pathogenic porcine respiratory coronavirus : Paul Prem S; Vaughn Eric M; Halbur Patrick G Ames, IA, United States Assigned to Iowa State University Research Foundation Inc


Contents of volume 41


Contents of volume 18


Cumulative Contents for 2008


title: Chapter 3 Antiviral drugs: general considerations

text: The development of an antiviral drug as well as of other drugs is a long process. In most programmes the screening and evaluation start using inhibition of virus multiplication in cell cultures, but in some instances the screening starts in animal models of different viral diseases. In these cases, the mechanism of action has to be analyzed after the in vivo effect has been found. It is not possible to specify precisely the time and resources required in a newly started project to find a compound active against a virus infection but 5-10 years is a reasonable estimation. For some viruses such as herpesviruses, where a number of active inhibitors are already known, the task is simpler than it is to find inhibitors of a virus such as influenza against which only a few active inhibitors have been reported. Evaluation of clinical efficacy in humans is a large and difficult part of the development of an antiviral drug. The number of uncontrolled clinical studies claiming efficacy of different drugs against viral diseases is depressingly large. It is essential to perform double-blind, placebo-controlled and statistically well evaluated studies to be able to judge the clinical efficacy of an antiviral drug. As the knowledge of the detailed natural history and molecular biology of viral diseases and viruses themselves increases, one will obviously have better opportunities to find new drugs. Methods such as X-ray diffraction measurement and NMR determinations will probably lead to a detailed understanding of the structures and interactions taking place at the active site of viral enzymes and their cellular counterparts.


Modern approaches to vaccines; molecular and chemical basis of virus virulence and immunogenicity: edited by Robert M. Chanock and Richard A. Lerner, Cold Spring Harbor Laboratory, 1984. $52.00 ($62.40 outside USA) (xxv+457 pages), ISBN 0 87969 165 4


Contents of volume 4


Contents of volume 36


Subject Index 2004


Contents of volume 11


Viruses and the pathogenesis of multiple sclerosis


Subject index of volume 162


Molecular diversity in the nucleocapsid protein of feline coronaviruses (FCoVs)


The Inhibitory Effects of Medicinal Herbs on SARS-CoV Entry In Vitro


P231 HEPATITIS C VIRUS POTENTLY ACTIVATES HUMAN CD161/MAIT (MUCOSAL ASSOCIATED INVARIANT T) CELLS


Single-dose Intranasal Delivery with DEF201 (Adenovirus Vectored Mouse Interferon-α) Protects Against Phlebovirus and Sars Coronavirus Challenge


5013719 Method of effecting immunosuppression: Terry L Bowlin assigned to Merrell Dow Pharmaceuticals Inc


4824785 Canine corona virus vaccine: William M Acree, Bobby Edwards, John W Black assigned to American Home Products Corp (Del)


Volume 12, 1989 volume contents and author index


Contents of volume 1


Subject index volumes 25–28


Contents of preventive veterinary medicine, volume 21


The acetone-butanol fermentation and related topics, 1980–1983: edited by J. D. Bu'lock and A. J. Bu'lock, Science and Technology Letters 1983. (iii + 139 pages) ISBN 0 946682 00 9


4904581 Method of detecting AIDS virus infection: Denis R Burger, Andrew S Goldstein assigned to Epitope Inc


Contents of volume 2


4904468 Canine coronavirus vaccine: Michael Gill, Stephen May assigned to Norden Laboratories Inc


Contents of Preventive veterinary medicine, volume 17


5013663 Canine corona virus vaccine: William M Acree, John W Black assigned to American Home Products Corporation


The improvement of porcine epidemic diarrhea vaccine production through in situ removal of ammonium ions by zeolite


Cumulative Subject Index for 2006 (Volumes 115–122)


5417986 Vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres : Reid Robert H; Boedeker Edgar; van Hamont John; Setterstrom Jean A Kensington, MD, United States Assigned to The United States of America as represented by the Secretary of the Army


title: I, 5. Treatment of viral gastroenteritis

text: Viral gastroenteritis (mainly after rotavirus infection) directly causes death through dehydration. Thus, the treatment and prevention of dehydration are the primary goals in caring for infants with gastroenteritis. Viral gastroenteritis can also inflict considerable nutritional insult on children because of anorexia, vomiting, malabsorption, and traditional therapies in which nutritionally poor diets are offered. This chapter discusses the treatment of the deficiencies of fluids, electrolytes, and nutrients. While there are already very good cost-effective strategies for correcting the sequelae of viral gastroenteritis, there is little yet available to effectively treat the acute symptoms of vomiting and diarrhea. The chapter discusses several potential modes of symptomatic therapy for viral gastroenteritis including probiotics, antivirals, passive immunotherapy, and antidiarrheals. The first major advance in the treatment of dehydration was the development of effective intravenous rehydration therapy.


Contents of volume 46


Summary of natural products isolated from marine organisms with antiviral activity against mouse coronavirus. : S. Cross and L. Moritz. Harbor Branch Oceanographic Institution, 5600 Old Dixie Highway, Ft. Pierce, Florida, 34946, U.S.A.


Thiazolides: A New Class of Broad-Spectrum Antiviral Drugs Targeting Virus Maturation


title: Identification of selected disease agents from calves on Costa Rican tropical cloud-forest dairy farms

text: Rotavirus, K99+ E. coli and coccidia were identified from feces of 10%, 13% and 37% of 300 selected dairy calves ⩽3 months of age, and from 26%, 36% and 45% of 42 Costa Rican dairy farms, respectively. Calf breeds were Holstein 68%, Jersey 27% and other breeds 5%. Median calf ages at identification of rotavirus, K99+ E. coli and coccidia were 14.5, 15, and 3 days, respectively. Differences between isolation rates for the wet and dry season were not statistically significant for any of the three agents. Prevalence of antibodies against infectious bovine rhinotracheitis and bovine parainfluenza-3 virus were 7% and 82%, respectively, for selected calves. Of calf sera tested for immunoglobulins, 9.5% were negative.


Contents of volume 5


Cumulative Subject Index for 2009


Contents of volume 14


Cumulative contents 2004


Vaccine biotechnology: edited by James L. Bittle and Frederick L. Murphy Academic Press, 1989. US$75.00 (iv + 444 pages) ISBN 0 12 039233 X


title: Host and viral factors that influence viral neurotropism II. Viral genes, host genes, site of entry and route of spread of virus

text: In the previous article in this series, we focused on how the interaction between viral cell attachment proteins and receptor molecules on the surface of host target cells played a major role in determining the cell and tissue tropism of many neurotropic viruses. In order to complete our review of viral factors that influence the tropism of viruses for the CNS, we will discuss the role of viral genes that function to specifically enhance the replication of viral proteins in certain cells or tissues (“tissue-specific enhancers and promoters”). We will then examine the ways in which host factors, including specific host genes, can influence resistance or susceptibility to certain types of neurotropic viral infections. Finally, we will conclude by reviewing how factors that involve the interaction of the host and the virus, such as the site of the viral entry and its route and method of spread, can influence the distribution of viral infection within the CNS.


5017372 Method of producing antibody-fortified dry whey: Donald Hastings assigned to Medicis Corporation


Contents of volume 77


Contents of volume 22


From pathological phenotype to candidate gene for Alzheimer's disease


Subject index (vols. 2–3)


Books received


Contents of Volume 65, issues 1 and 2


Related elsevier virology titles content alert


Cumulative Contents for 2010


Cumulative Contents for 2007


5422109 Fluid vaccines and active principle vehicles containing a metabolizable oil : Brancq Bernard; Trouve Gerard Le Chesnay, France Assigned to Societe d'Exploitation de Produits pour les Industries Chimiques (S E P P I C)


Author Index 2004


RNA genetics vols. 1–3: Edited by Esteban Domingo, John J Holland and Paul Alquist published by CRC Press, 1988


Author Index to Volume 65, issues 1 and 2


Cumulative Contents for 2009


Twenty-Fourth International Conference on Antiviral Research - Front Pages


Contents of volume 21


Cumulative Contents for 2006 (Volumes 115–122)


Cumulative Author Index for 2006 (Volumes 115–122)


Contents of Volume 73


Contents of volume 9


4824666 Method of large scale growth of toxoplasmic microorganisms: D Craig Wright assigned to The United States of America as represented by the Secretary of the Army


Cumulative Author Index for 2008


4902616 Process for the preparation of capsular polysaccharides of staphylococci, the polysaccharides obtained, uses of these polysaccharides and strains for carrying out of the process: Jean-Michel Fournier, Anne Bouvet, Alain Boutonnier, Paris, France assigned to Institut Pasteur


Contents of volume 45


Cumulative Subject Index for 2007


Contents of volume 10


A Novel Method—Amenable for High-throughput Screening Purposes—to Quantify Antiviral Activity Against Viruses that Induce Limited CPE


Contents of volume 13


Interferons: what future?


Induction of Interferon Gamma Inducible Protein 10 by SARS-CoV Infection, Interferon Alfacon 1 and Interferon Inducer in Human Bronchial Epithelial Calu-3 Cells and BALB/c Mice


Cumulative Subject Index for 2008


title: Dairy calf management, morbidity and mortality in Ontario Holstein herds. IV. Association of management with mortality

text: Associations between heifer calf management and mortality were studied on 104 randomly selected Holstein dairy farms in southwestern Ontario between October 1980 and July 1983. At the farm level, data were stratified by season, with two six-month seasons (winter and summer) per year. The odds of farms with particular management strategies having above-median morbidity were calculated. At the individual calf level, the odds of a calf being treated, controlling for farm of origin and month of birth, were calculated for different management practices. Larger farms had significantly greater odds of experiencing mortality than smaller farms in both winter and summer. Farms which had policies of attending calvings and ensuring that calves received their first colostrum had significantly lower odds of experiencing winter mortality than farms which did not have these policies. Farms which housed calves in hutches had significantly lower odds, and those which housed calves in group pens had significantly higher odds, of experiencing summer mortality, than farms which used individual indoor calf-pens. A policy of teat removal between four weeks of age and weaning was associated with increased odds of summer mortality. At the individual calf level, calving ease, sire, navel treatment, assistance at first colostrum feeding, administration of vitamins A, D and E and anti-scour vaccines to the pregnant dam, and place of calving, were all associated with significantly altered odds of dying. However, several interactions entered the statistical models, and the effects of those management practices were not all straightforward.


Tumor necrosis factor induces MHC class I antigen expression on mouse astrocytes


Biotechnology applied to the diagnosis of animal diseases: Scientific and technical review, vol. 12 no. 2, June 1993. Office International des Epizooties, Paris, France, 1993, 353 pp., US$40.00/FrF200, ISBN 92-9044-323-5.


Author index volumes 25–28


Contents of volume 7


Author index of volume 166


Contents of volume 16


Cumulative Contents for 2005


5016644 Urine testing module and method of collecting urine antigen: Raouf A Guirguis assigned to La Mina Ltd


Cumulative Author Index for 2007


Volume contents and author index


Author index of volume 162


Cumulative Author Index for 2005


Cumulative Subject Index for 2010


Establishment of an ELISA-based primary antiviral screen and plaque reduction based confirmatory assay for evaluation of compounds against the filovirus ebola under maximum biological containment conditions (BL-4) : J.W. Huggins, Z.X. Zhang and T.P. Monath. Department of Antiviral Studies, Virology Division, U.S. Army Medical Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, 21701-5011, USA


Volume 30 contents and author index 2007


title: Requirements of Data Visualisation Tools to Analyse Big Data: A Structured Literature Review

text: The continual growth of big data necessitates efficient ways of analysing these large datasets. Data visualisation and visual analytics has been identified as a key tool in big data analysis because they draw on the human visual and cognitive capabilities to analyse data quickly, intuitively and interactively. However, current visualisation tools and visual analytical systems fall short of providing a seamless user experience and several improvements could be made to current commercially available visualisation tools. By conducting a systematic literature review, requirements of visualisation tools were identified and categorised into six groups: dimensionality reduction, data reduction, scalability and readability, interactivity, fast retrieval of results, and user assistance. The most common themes found in the literature were dimensionality reduction and interactive data exploration.


title: The Characteristics of Digital Entrepreneurship and Digital Transformation: A Systematic Literature Review

text: The characteristics of digital entrepreneurship and digital transformation and how they are related, is complex and important to understand in this digital age. Such an understanding of digital entrepreneurship is perceived as a key pillar for economic growth, job creation and innovation. However, a number of issues regarding digital entrepreneurship and digital transformation are prevalent, inhibiting digital entrepreneurs to optimise the advantages that digital entrepreneurship contributes towards business value. Therefore, the aim of this research paper is to investigate digital entrepreneurship and digital transformation, their characteristics and inter-relationships. Data extracted and analysed through a structured analysis process, recognises and discusses the characteristics of digital entrepreneurship and digital transformation. The characteristics are reported by employing the Dynamic Capabilities Theory as the structure. By understanding the characteristics of digital entrepreneurship and digital transformation, individuals and organisations may either create new business ventures or transform existing businesses through the development of novel digital technologies or the innovative application of such technologies.


title: Unsupervised Anomaly Detection of Healthcare Providers Using Generative Adversarial Networks

text: Healthcare fraud is considered a challenge for many societies. Health care funding that could be spent on medicine, care for the elderly or emergency room visits are instead lost to fraudulent activities by materialistic practitioners or patients. With rising healthcare costs, healthcare fraud is a major contributor to these increasing healthcare costs. This study evaluates previous anomaly detection machine learning models and proposes an unsupervised framework to identify anomalies using a Generative Adversarial Network (GANs) model. The GANs anomaly detection (GAN-AD) model was applied on two different healthcare provider data sets. The anomalous healthcare providers were further analysed through the application of classification models with the logistic regression and extreme gradient boosting models showing good performance. Results from the SHapley Additive exPlanation (SHAP) also signifies that the predictors used explain the anomalous healthcare providers.


title: Categorization of Factors Influencing Community Health Workers from a Socio-Technical Systems Perspective

text: In low-and-middle-income countries (LMICs), community health workers (CHWs) are often seen as a connecting bridge between two dynamic and overlapping systems- the community and formal health systems. Although the importance of CHWs is acknowledged, there is minimal aggregated evidence contributing towards understanding their position, technological capabilities, barriers and facilitators of their effectiveness in the South African context. Despite the widespread enthusiasm around the potential that mobile health (mHealth) technology holds in extending healthcare through CHW to underserved communities, an understanding of mHealth’s various implications in a developing world context is imperative to appreciate both the community and health systems context. The CHWs within this context need to assume multiple roles as they work and live amongst and in the community. The study argues that by examining their multiple roles as part of the healthcare continuum and from within the community setting, appropriating technological solutions can be conceptualized to facilitate and enhance their impact and visibility. This research article then aims to articulate the key conceptual factors which should be considered when implementing technological solutions for CHWs within the South African context. The aim is operationalized by means of the best-fit framework synthesis method to explore the body of knowledge towards presenting a conceptual understanding through a categorization of Factors Influencing Community Health Workers from a Socio-Technical Systems Perspective.


title: SMME Readiness for Smart Manufacturing (4IR) Adoption: A Systematic Review

text: Smart manufacturing, Industry 4.0 and Smart Factory are phenomena regarded as a key necessity for Small, Medium and Micro Businesses (SMMEs) worldwide. Even though these 4(th) Industrial Revolution (4IR) phenomena are generally used interchangeably, this paper sought to identify how SMME readiness for smart manufacturing has been investigated through a systematic review. The systematic review was conducted through the lens of Nooteboom, and Tornatzky and Klein’s research on technological innovation in SMMEs based on Rogers’ diffusion of innovations theory. The findings reveal that there is little to no research on smart manufacturing in relation to SMMEs in low-income countries particularly the African continent. The results also show that smart manufacturing is still an emergent phenomenon with disparate definitional challenges. These definitional challenges make the adoption of smart manufacturing innovations a challenge in resource-constrained contexts; but similarly present an opportunity for new definitions and theories in such contexts. The little research often treats SMMEs homogenously and as such misses their important heterogeneous (sector or industry specific) nature. Few research studies investigate SMME awareness (adequate knowledge) or make explicit the benefits (relative advantage) of smart manufacturing. Even fewer studies are explicit on the smart manufacturing technologies that are relevant for different SMME sectors. Smart manufacturing is identified as incompatible with SMME characteristics, that is SMMEs lack expertise/skills to comprehend the complexity of smart manufacturing, and also lack financial and human resources to implement smart manufacturing. Given that awareness, relative advantage, complexity and compatibility are critical barriers for SMME smart manufacturing readiness/adoption, there is a critical need for research to focus on these factors in particular for the context of resource constrained low-income country environments.


title: A Framework for Industrial Internet of Things

text: The Industrial Internet of Things (IIoT) is a new concept that has the potential to add value to any industrial organisation that wants to embark on the implementation thereof. Due to this newness of IoT in industrial operations, an increase in cost and maturity in terms of data handling, together with only a few implementations. There was a gap in available practical IIoT frameworks that could aid interested parties in the understanding of the constructs of IIoT and the practical implications of implementation. Within this study, we propose an Industrial Internet of Things framework intended to aid academic, technical and management persons in understanding the different considerations of the Industrial Internet of Things. This framework could also apply as a basis for implementation considerations.


title: A Systematic Review of Implementation Challenges in Public E-Procurement

text: Challenges faced in public e-procurement implementation are not well understood despite past studies focusing on the phenomenon. This paper, which is based on a systematic literature review of academic papers, seeks to synthesize and examine the key challenges impeding public e-procurement implementation. These challenges are categorized using the Technology-Organization-Environment (TOE) framework as follows (1) Technological challenges: e-procurement acceptance and usage, disruptive innovation characteristic of e-procurement, use of digital signatures, security and privacy of technology and technical aspects of e-procurement (2) Organizational challenges: stakeholders’ behavior, leaders’ behavior, shortcomings in leadership, lack of training and skilled personnel, resistance to change, organizational power and politics and the creation of public value underlying e-procurement (3) Environmental/Contextual challenges: regulatory framework for public procurement, Small-and-Medium-Size Enterprise issues, and context of the country. Key e-procurement implementation challenges are grounded in human and contextual issues. So we recommend more case studies on public e-procurement implementation in the future.


title: A Broker-Based Framework for the Recommendation of Cloud Services: A Research Proposal

text: Finding and comparing appropriate cloud services that best fit cloud service consumer requirements can be a complex, time-consuming and cost-intensive process, especially for small and medium-sized enterprises. Since there is no “one-fits-all” cloud service provider, companies face the challenge of selecting and combining services from different vendors to meet all their requirements. Therefore, this paper calls for the design of a cloud brokering framework that would enable faster and easier selection of cloud services by recommending appropriate services through a matchmaking system. Drawing on previously conducted studies and considering current issues and practical experiences both from provider and user perspectives, we propose a framework that would identify, rank and recommend cloud services from multiple modules and components to individual consumers. Furthermore, we contribute an early-stage design of a cloud broker framework that considers cloud-service consumers’ sourcing preferences while making new cloud-sourcing decisions and that can be used in the selection and adoption phase of implementing cloud services and/or as part of a multicloud strategy.