Cell membrane bound N1/N2/N1/N2 NMDA receptor. Typical NMDA-receptors have 4 subunits - only 2 are shown. Normal flow of Ca2+, Na+ and K+ ions is shown alongside with the regular membrane potential (+ and - signs) and some of the ligand binding sites.
ATD: amino terminal domain.LBD: ligand-­binding domain. LBD can bind glutamine (Glu, agonist) and D-serine (D-Ser) or glycine (Gly) coagonists.TMD: transmembrane domains. TMDs are composed of M1-4 segments.CTD: intracellular carboxyl terminal domain.Structure and information adapted from:

Hashimoto, Kenjii (ed.). (2017). The NMDA receptors. Mori, Hisashi. p. 7-8. ISBN 9783319497952. doi:10.1007/978-3-319-49795-2.
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