a – Box plot of the antibody-producing cells (AFC) count in the spleen after intramuscular administration of secretome; b – Box plot of the antibody-producing cells (AFC) count in the spleen after subcutaneous administration of secretome; c – Box plot of the hemagglutinin (HA) titer in the blood serum after intramuscular administration of secretome; d – Box plot of the hemagglutinin (HA) titer in the blood serum after subcutaneous administration of secretome; e – Combo chart of AFC count and HA titer after intramuscular administration of secretome; f – Combo chart of AFC count and HA titer after subcutaneous administration of secretome
Statistical analysis using the Mann–Whitney–Wilcoxon U-test: 1 – significant difference compared to Control (p ≤ 0.05); 2 – significant difference compared to Control (p ≤ 0.01); 3 – significant difference compared to Thymalin (p ≤ 0.05); 4 – significant difference compared to Thymalin (p ≤ 0.01); 5 – significant difference between routes of administration (p ≤ 0.01)
Own work
Vitalii moskalov