This is the insignia for STS-98, which marks a major milestone in assembly of the International Space Station (ISS).
Atlantis' crew will deliver the United States Laboratory, Destiny, to the ISS. Destiny will be the centerpiece of the ISS, a weightless laboratory where expedition crews will perform unprecedented research in the life sciences, materials sciences, Earth sciences, and microgravity sciences. The laboratory is also the nerve center of the Station, performing guidance, control, power distribution, and life support functions. With Destiny's arrival, the Station will begin to fulfill its promise of returning the benefits of space research to Earth's citizens.
The crew patch depicts the Space Shuttle with Destiny held high above the payload bay just before its attachment to the ISS. Red and white stripes, with a deep blue field of white stars, border the Shuttle and Destiny to symbolize the continuing contribution of the United States to the ISS. The constellation Hercules, seen just below Destiny, captures the Shuttle and Station's team efforts in bringing the promise of orbital scientific research to life. The reflection of Earth in Destiny's window emphasizes the connection between space exploration and life on Earth.
http://spaceflight.nasa.gov/gallery/images/shuttle/sts-98/html/sts098-s-001.html
https://commons.wikimedia.org/w/index.php?title=File:ISS_Utilization_Guide_2015.pdf&amp;page=95