The Tsuji–Wilkinson decarbonylation reaction is a method for the decarbonylation of aldehydes and some acyl chlorides. The reaction name recognizes Jirō Tsuji, whose team first reported the use of Wilkinson's catalyst (RhCl(PPh)) for these reactions:
:RC(O)X + RhCl(PPh) → RX + RhCl(CO)(PPh) + PPh
Although decarbonylation can be effected by several transition metal complexes, Wilkinson's catalyst has proven the most effective.