Ann E. McDermott is an American biophysicist who uses nuclear magnetic resonance to study the structure, function, and dynamics of proteins in native-like environments. She is currently the Esther Breslow Professor of Biological Chemistry and Chair of the Educational Policy and Planning Committee of the Arts and Sciences at Columbia University. She has also previously served as Columbia's Associate Vice President for Academic Advising and Science Initiatives in the Arts and Sciences. She is an elected member of both the American Academy of Arts and Sciences and the National Academy of Sciences.