De Hevesy married Pia Riis in 1924. They had one son and three daughters together, one of whom (Eugenie) married a grandson of the Swedish Nobel laureate Svante Arrhenius. De Hevesy died in 1966 at the age of eighty and was buried in Freiburg. In 2000, his body was moved to the Kerepesi Cemetery in Budapest, Hungary. He had published a total of 397 scientific documents, one of which was the Becquerel-Curie Memorial Lecture, in which he had reminisced about the careers of pioneers of radiochemistry. At his family's request, his ashes were interred at his birthplace in Budapest on 19 April 2001.
On 10 May 2005 the Hevesy Laboratory was founded at Risø National Laboratory for Sustainable Energy, now Technical University of Denmark,  DTU Nutech. It was named after George de Hevesy as the father of the isotope tracer principle under the initiative of the lab's first director, Prof. Mikael Jensen.