Observations relating to CAM were first made by de Saussure in 1804 in his Recherches Chimiques sur la Végétation. Benjamin Heyne in 1812 noted that Bryophyllum leaves in India were acidic in the morning and tasteless by afternoon. These observations were studied further and refined by Aubert, E. in 1892 in his Recherches physiologiques sur les plantes grasses and expounded upon by Richards, H. M. 1915 in Acidity and Gas Interchange in Cacti, Carnegie Institution. The term CAM may have been coined by Ranson and Thomas in 1940, but they were not the first to discover this cycle. It was observed by the botanists Ranson and Thomas, in the succulent family Crassulaceae (which includes jade plants and Sedum). The name "Crassulacean acid metabolism" refers to acid metabolism in Crassulaceae, and not the metabolism of "crassulacean acid"; there is no chemical by that name.