Availability of modular metal centers and organic building blocks generate wide diversity in synthetic versatility. Their applications range from industrial use to chemiresistive sensors. The ordered structure of the frame is largely determined by the coordination geometry of the metal and directionality of functional groups upon the organic linker. Consequently, MOFs contain highly defined pore dimensions when compared with conventional amorphous nanoporous materials and polymers. Reticular Synthesis of MOFs is a term that has been recently coined to describe the bottom-up method of assembling cautiously designed rigid molecular building blocks into prearranged structures held together by strong chemical bonds. The synthesis of two-dimensional MOFs begins with the knowledge of a target "blueprint" or a network, followed by identification of the required building blocks for its assembly.
By interchanging metal centers and organic ligands, one can fine-tune electronic and magnetic properties observed in MOFs. There have been recent efforts synthesize conductive MOFs using triyphenylene linkers. Additionally, MOFs have been utilized as reversible chemiresistive sensors.