The acceptable daily intake (ADI) is  0–4 mg/kg under both EU and WHO/FAO guidelines.
Sunset yellow FCF has no carcinogenicity, genotoxicity, or developmental toxicity in the amounts at which it is used.
It has been claimed since the late 1970s, under the advocacy of Benjamin Feingold, that sunset yellow FCF causes food intolerance and ADHD-like behavior in children, but there is no scientific evidence to support these broad claims.  It is possible that certain food colorings may act as a trigger in those who are genetically predisposed, but the evidence is weak.