In June 1791, Lavoisier made a loan of 71,000 livres to Pierre Samuel du Pont de Nemours to buy a printing works so that du Pont could publish a newspaper, La Correspondance Patriotique. The plan was for this to include both reports of debates in the National Constituent Assembly as well as papers from the Academy of Sciences. The revolution quickly disrupted the elder du Ponts first newspaper, but his son E.I. du Pont soon launched Le Republicain and published Lavoisiers latest chemistry texts.
Lavoisier also chaired the commission set up to establish a uniform system of weights and measures which in March 1791 recommended the adoption of the metric system. The new system of weights and measures was adopted by the Convention on 1 August 1793. Lavoisier was one of the 27 Farmers General who, by order of the Convention, were all to be detained. Although temporarily going into hiding, on 30 November 1793 he handed himself into the Port Royal convent for questioning. He claimed he had not operated on this commission for many years, having instead devoted himself to science.
Lavoisier himself was removed from the commission on weights and measures on 23 December 1793, together with mathematician Pierre-Simon Laplace and several other members, for political reasons.
One of his last major works was a proposal to the National Convention for the reform of French education. He also intervened on behalf of a number of foreign-born scientists including mathematician Joseph Louis Lagrange, helping to exempt them from a mandate stripping all foreigners of possessions and freedom.