A sample Irwin screen includes overt behavior observations and autonomic observations:
Overt Behavior
* increased activity
* decreased activity
* sedation
* tremor
* convulsions
** myoclonic
** tonic/clonic
* straub tail
* stereotypy
* increased exploration
* decreased exploration
* ataxia
* weakness
* catalepsy
* pain threshold (tail pinch)
* loss of righting reflex
* writhing (i.p. administration)
Autonomic Observations
* piloerection
* diarrhoea
* exophthalmos
* salivation
* vasoconstriction
* vasodilatation
* cyanosis
* lacrymation
* ptosis
* miosis
* mydriasis
* hypothermia