Research on the cytotoxic and anticlastogenic activities of the cyclamen genus has been limited. In the 1950s and 1960s little research was done on the toxic saponin cyclamin, but no further investigation has recently been performed. Cyclamin, a triterpenoid pentasaccharidic saponin, has previously been extracted from different cyclamen species, including Cyclamen mirabile, Cyclamen trocopteranthum, Cyclamen libanoticum and Cylamen persicum.