Some reactions that are accomplished using M-Josiphos complexes as catalyst are listed below.  Other reactions where Josiphos ligands can be used are: hydrogenation of C=N, C=C and C=O bonds, catalyzed allylic substitution, hydrocarboxylation, Michael addition, allylic alkylation, Heck-type reactions, oxabicycle ring-opening, and allylamine isomerization. 
; Hydroboration of styrene
:Conducted at -78 °C, the above reaction has e.e.s up to 92% and TOF of 5-10 h.  Hayashis Rh-binap complex gives better yield.
; Hydroformylation of Styrene
:This reaction scheme yields of up to 78% ee of the (R) product, but low TON and TOF of 10-210 and 1-14h (respectively).
;Reductive amination
:Above is the preparation of (S)-metolachlor. Good yields and a 100% conversion crucially require AcOH solvent.
;Hydrogenation of exocyclic methyl imine
:This key step to synthesize a HIV integrase inhibitor, Crixivan, is one of the few known homogeneous heteroarene hydrogenation reactions.  Bulky R groups increase the catalyst's performance, with 97% e.e. and TON and TOF of 1k and 8 min, respectively.
;Asymmetric synthesis of chromanoylpyridine derivatives
:This reaction, for an intermediate in synthesis of an antihypertensive and anti-alopecic chromanoylpyridine derivative, exhibits high enantioselectivity, but low activity.