Minimizing harmful exposure to pesticides can be achieved by proper use of personal protective equipment, adequate reentry times into recently sprayed areas, and effective product labeling for hazardous substances as per FIFRA regulations. Training high-risk populations, including agricultural workers, on the proper use and storage of pesticides, can reduce the incidence of acute pesticide poisoning and potential chronic health effects associated with exposure. Continued research into the human toxic health effects of pesticides serves as a basis for relevant policies and enforceable standards that are health protective to all populations.