The Scripps Research Institute has a portfolio of click-chemistry patents. Licensees include Invitrogen, Allozyne, Aileron, Integrated Diagnostics, and the biotech company , a BASF spin-off created to sell products made using click chemistry. Moreover,  holds a worldwide exclusive license for the research and diagnostic market for the nucleic acid field.
Fluorescent azides and alkynes are also produced by companies such as Cyandye.