The growth and development of normal cells follow a cycle in a controlled and ordered manner. When they are damaged, they will die through a process called apoptosis. However, apoptosis is disrupted in cancer cells, allowing them to divide and grow uncontrollably, potentially invading other tissues or organs. They will not undergo the normal death process of body cells.
Hepatocellular carcinoma (HCC) is a prevalent type of liver cancer that accounts for over 80% of cases. It is lethal cancer due to the remarkable drug tolerance, spread potential and high chance of relapse. Scientists have carried out many kinds of research in finding out the risk factors of HCC progression.