Data resulting from toxicity studies that is integrated in to the ECOTOX database is subjected to a screening and quality assurance criteria developed by the EPA and the Office of Pesticide Programs (OPP). In order for study results to be accepted by the EPA and OPP the toxicity study must follow or consist of the following:
*     The toxic effects are related to single chemical exposure;
*     The toxic effects are on an aquatic or terrestrial plant or animal species;
*     There is a biological effect on live, whole organisms;
*     A concurrent environmental chemical concentration/dose or application rate is reported; and
*     There is an explicit duration of exposure.
In addition to the criteria listed above, the following criteria, which are discussed in further detail in Attachment I, are applied by OPP as a further screen of acceptability:
*     Toxicology information is reported for a chemical of concern to OPP;
*     The article is published in the English language;
*     The study is presented as a full article;
*     The paper is a publicly available document;
*     The paper is the primary source of the data
*     A calculated endpoint is reported;
*     Treatment(s) are compared to an acceptable control;
*     The location of the study (e.g., laboratory vs. field) is reported; and
*     The tested species is reported and verified.