Ultrasensitivity can be achieved through several mechanisms: 
#Multistep mechanisms (examples: cooperativity) and multisite phosphorylation
#Buffering mechanisms (examples: decoy phosphorylation sites) or stoichiometric inhibitors
#Changes in localisation (such as translocation across the nuclear envelope)
#Saturation mechanisms (also known as zero-order ultrasensitivity)
#Positive feedback
#Allovalency
#Non-Zero-Order Ultrasensitivity in Membrane Proteins
#Dissipative Allostery