Physicians prescribed various forms of lead to heal ailments ranging from constipation to infectious diseases such as the plague. Lead was also used to preserve or sweeten wine. Lead arsenate is used in insecticides and herbicides. Some organic lead compounds are used as industrial biocides: thiomethyl triphenyllead is used as an antifungal agent, cotton preservative, and lubricant additive; thiopropyl triphenyllead as a rodent repellant; tributyllead acetate as a wood and cotton preservative; tributyllead imidazole as a lubricant additive and cotton preservative.