Stereochemistry is conveniently denoted in skeletal formulae:
The relevant chemical bonds can be depicted in several ways:
* Solid lines represent bonds in the plane of the paper or screen.
* Solid wedges represent bonds that point out of the plane of the paper or screen, towards the observer.
* Hashed wedges or dashed lines (thick or thin) represent bonds that point into the plane of the paper or screen, away from the observer.
* Wavy lines represent either unknown stereochemistry or a mixture of the two possible stereoisomers at that point.
*An obsolescent depiction of hydrogen stereochemistry that used to be common in steroid chemistry is the use of a filled circle centered on a vertex (sometimes called H-dot/H-dash/H-circle, respectively) for an upward pointing hydrogen atom and two hash marks next to vertex or a hollow circle for a downward pointing hydrogen atom.  
An early use of this notation can be traced back to Richard Kuhn who in 1932 used solid thick lines and dotted lines in a publication. The modern solid and hashed wedges were introduced in the 1940s by Giulio Natta to represent the structure of high polymers, and extensively popularised in the 1959 textbook Organic Chemistry by Donald J. Cram and George S. Hammond.
Skeletal formulae can depict cis and trans isomers of alkenes. Wavy single bonds are the standard way to represent unknown or unspecified stereochemistry or a mixture of isomers (as with tetrahedral stereocenters). A crossed double-bond has been used sometimes; it is no longer considered an acceptable style for general use but may still be required by computer software.