Sleeping pills, including eszopiclone, have been associated with an increased risk of death.
Hypersensitivity to eszopiclone is a contraindication to its use. The presence of liver impairment, lactation and activities requiring mental alertness (e.g., driving) may be considered when determining frequency and dosage.
* unpleasant taste
* headache
* peripheral edema
* chest pain
* abnormal thinking
* behavior changes
* depression
* hallucinations
* sleep driving and sleepwalking
* dry mouth
* rash
* altered sleep patterns
* impaired coordination
* dizziness
* daytime drowsiness
* itching
* painful or frequent urination
* back pain
* aggressive behavior
* confusion
* agitation
* suicidal thoughts
* depersonalization
* amnesia
A 2009 meta-analysis found a 44% higher rate of mild infections, such as pharyngitis or sinusitis, in people taking eszopiclone or other hypnotic drugs compared to those taking a placebo.