* Carotid bodies and aortic bodies detect changes primarily in pCO and H ion concentration. They also sense decrease in partial pressure of O, but to a lesser degree than for pCO and H ion concentration.
* The chemoreceptor trigger zone is an area of the medulla in the brain that receives inputs from blood-borne drugs or hormones, and communicates with the vomiting center (area postrema) to induce vomiting.
* Primary cilia play important roles in chemosensation. In adult tissues, these cilia regulate cell proliferation in response to external stimuli, such as tissue damage. In humans, improper functioning of primary cilia is associated with important diseases known as ciliopathies.