The signal of mass-independent fractionation of sulfur isotopes, known as MIF-S, correlates with the end of Xe isotope fractionation. During the Great Oxidation Event (GOE), the ozone layer formed when O rose, accounting for the end of the MIF-S signature. The disappearance of the MIF-S signal has been regarded as changing the redox ratio of Earth's surface reservoirs. However, potential memory effects of MIF-S due to oxidative weathering can lead to large uncertainty on the process and chronology of GOE. Compared to the MIF-S signals, hydrodynamic escape of Xe is not affected by the ozone formation and may be even more sensitive to O availability, promising to provide more details about the oxidation history of Earth.