CDE is defined by the United States Nuclear Regulatory Commission in Title 10, Section 20.1003, of the Code of Federal Regulations (10 CFR 20.1003), such that "The Committed dose equivalent, CDE (H,50) is the dose to some specific organ or tissue of reference (T) that will be received from an intake of radioactive material by an individual during the 50-year period following the intake".
"The calculation of the committed effective dose equivalent (CEDE) begins with the determination of the equivalent dose, H, to a tissue or organ, T. Where D,R is the absorbed dose in rads (one gray, an SI unit, equals 100 rads) averaged over the tissue or organ, T, due to radiation type, R, and W is the radiation weighting factor. The unit of equivalent dose is the rem (sievert, in SI units)."