A couple of Escherichia coli mutant strains have been bioengineered to ferment glucose under aerobic conditions.  One group developed the ECOM3 (E. coli cytochrome oxidase mutant) strain by removing three terminal cytochrome oxidases (cydAB, cyoABCD, and cbdAB) to reduce oxygen uptake.  After 60 days of adaptive evolution on glucose media, the strain displayed a mixed phenotype.  In aerobic conditions, some populations' fermentation solely produced lactate, while others performed mixed-acid fermentation.