Quinapril, sold under the brand name Accupril by the Pfizer corporation. It a medication used to treat high blood pressure (hypertension), heart failure, and diabetic kidney disease. It is a first line treatment for high blood pressure. It is taken by mouth.
Common side effects include headaches, dizziness, feeling tired, and cough. Serious side effects may include liver problems, low blood pressure, angioedema, kidney problems, and high blood potassium. Use in pregnancy and breastfeeding is not recommended. It is among a class of drugs called ACE inhibitors and works by decreasing renin-angiotensin-aldosterone system activity.
Quinapril was patented in 1980 and came into medical use in 1989. It is available as a generic medication. In 2020, it was the 253rd most commonly prescribed medication in the United States, with more than 1million prescriptions.