Gene guns have also been used to deliver DNA vaccines.
The delivery of plasmids into rat neurons through the use of a gene gun, specifically DRG neurons, is also used as a pharmacological precursor in studying the effects of neurodegenerative diseases such as Alzheimer's disease.
The gene gun has become a common tool for labeling subsets of cells in cultured tissue.  In addition to being able to transfect cells with DNA plasmids coding for fluorescent proteins, the gene gun can be adapted to deliver a wide variety of vital dyes to cells.
Gene gun bombardment has also been used to transform Caenorhabditis elegans, as an alternative to microinjection.