Rokushō is used to treat a number of metals, including raw natural copper, which holds impurities, purified copper, and copper alloy mixes with two to five metals, to produce irogane metals, including: shakudō, an alloy of copper and gold, which becomes black to dark blue-violet; shibuichi, an alloy of fine silver and copper (in a higher percentage than sterling), which turns grey to misty aquamarine or other shades of blue to green; kuromido which becomes dark coppery black.
Rokushō was generally used to patinate all types of mokume-gane ("wood grain metal") as well.
Although other patination agents can be used on these metals, some artisans prefer the rich colors achieved with traditional rokushō in the niiro process.
These metals are becoming increasingly popular in high-end artistic jewelry, especially in bi-metals (a layer of the alloy fused to another metal such as sterling).  Because rokushō has a dramatically different effect on sterling silver than on the alloys typically fused to it in bi-metals, a common technique in art jewelry is to engrave through the alloy layer in a pattern to reveal the silver underneath prior to patination.  This provides a rich contrast in color, highlighting the pattern.