It is crucial to note that although most of the gene deserts explored here are essential, it could be that the majority of the contents in gene deserts are still likely to be inessential and disposable. Naturally, this is not to say that the roles that gene deserts play are inessential or unimportant, rather than their functions may include buffering effects. An example of essential gene deserts with inessential DNA content are the telomeres that protect the ends of genomes. Telomeres can be categorized as true gene deserts, given that they solely contain repeats of TTAGGG (in humans) and do not have apparent protein-coding functions. Without these telomeres, human genomes would be severely mutated within a fixed number of cell cycles. On the other hand, since telomeres do not code for proteins, their loss ensures that there is no effect in important processes. Therefore, the term “junk” DNA should no longer be applied to any region of the genome; every portion of the genome should play a role in protecting, regulating, or repairing the protein coding regions that determine the functions of life. Although there is still much to learn about the nooks and crannies of the immense (yet limited) human genome, with the aid of various new technologies and the synthesis of the full human genome, we may perhaps unravel a great collection of secrets in the approaching years about the marvels of our genetic code.