The scientist was the first to draw attention to the special importance of studying the migration of relatively short-lived radioelements in the Earth's crust for solving general geological and geochemical problems (1926). V. G. Khlopin pointed out a number of questions of these disciplines, which imply solution by the proposed methods: determination of sequence in geological and geochemical processes, determination of absolute age of relatively young and very young geological formations, and a number of other thematic areas. Migrations of uranium and radium were subjected to experimental study.