Dr Mukherjee was able to foresee how basic soil colloid studies could be of help in understanding many of the soil properties and problems. He brought to use in 
the study of the soil all the tools and techniques he had been developing and improving through years of patient research. In 1942, with N.C. Sen Gupta, he developed a
simple rotary viscometer for the study of anomalous viscous properties. In 1944, he developed the method of differentiation of crude oils based on chromatography capillary analysis and fluorescence in UV light.