Angela Casini joined the École Polytechnique Fédérale de Lausanne as a Principal Investigator in 2008. She moved to the University of Groningen in 2011, where she was made a Rosalind Franklin Fellow. She was made a Chair of Medicinal Chemistry at Cardiff University in 2015, and has served as Director of Postgraduate Teaching from 2018. She spent 2016 as a Visiting Professor at the Technical University of Munich.