Dynamic kinetic resolution under Curtin–Hammett conditions has also been applied to enantioselective lithiation reactions. In the reaction below, it was observed that product enantioselectivities were independent of the chirality of the starting material. The use of (&minus;)-sparteine is essential to enantioselectivity, with racemic product being formed in its absence. 
Equilibration between the two alkyllithium complexes was demonstrated by the observation that enantioselectivity remained constant over the course of the reaction. Were the two reactant complexes not rapidly interconverting, enantioselectivity would erode over time as the faster-reacting conformer was depleted.