From 1989 to 1995, Grasselli Brown worked as a distinguished visiting professor and director of research enhancement at her alma mater, Ohio University. She has also served as a chair of the board of trustees, chair of the Ohio Board of Regents, a Foundation Board trustee for nine years, and a member of the Cutler Scholars Board of governors.
She has served on numerous committees and boards such as the National Science Foundation Advisory Committee for Analytic Chemistry (1982–1984), the Energy Research Advisory Board of the U.S. Department of Energy (1987–1989), the visiting committee of the National Institute of Standards and Technology (1988–1991), and the Smithsonian Institution's exhibition advisory board (1990–1994). She chaired the U.S. National Committee of the International Union of Pure and Applied Chemistry from 1992 to 1995.
Grasselli Brown edited the international journal, Vibrational Spectroscopy. She is a member of the American Chemical Society, Coblentz Society, Federation of Analytical Chemistry and Spectroscopy Societies, and the American Association for the Advancement of Science. She was the president of the Society for Applied Spectroscopy in 1970. She is active in promoting womens careers as a member of the International Womens Forum and National Research Council's Committee on Women in Science and Engineering. She is an avid supporter of women in the workplace and defends part-time work for women, equal salaries, and corporate child-care facilities.
Grasselli Brown has given over a hundred talks at scientific conferences, one hundred seminars for graduate students, and over five hundred lectures to the general public.  She continues to be widely requested as a speaker and consultant on industrial and environmental problems. She travels to Eastern Europe to teach the use of spectroscopy for soil, air, and water pollution issues.