Methylation of adenosine does not affect its ability to base-pair with thymidine or uracil, so N-methyladenosine (mA) cannot be detected using standard sequencing or hybridization methods. This modification is marked by the methylation of the adenosine base at the nitrogen-6 position. It is abundantly found in polyA+ mRNA; also found in tRNA, rRNA, snRNA, and long ncRNA.