Dry ice sublimates at  and is a cryogenic hazard. Proper PPE, including appropriate gloves, goggles, and apron are required when handling, and contact with bare skin should be avoided. Dry ice will naturally sublimate away in ambient air, but should always be kept in a well-ventilated area to prevent hazardous buildup of carbon dioxide gas or displacement of oxygen. Symptoms of carbon dioxide overexposure include dizziness, headache, shortness of breath, hyperventilation, anxiety, and in certain individuals, panic attacks.