In the U.S., standard methods have been established by the National Institute for Occupational Safety and Health (NIOSH) and another by U.S. OSHA. Each method uses a single component solvent; butanol and hexane cannot be sampled, however, on the same sample matrix using the NIOSH or OSHA method.
VOCs are quantified and identified by two broad techniques. The major technique is gas chromatography (GC). GC instruments allow the separation of gaseous components.  When coupled to a flame ionization detector (FID) GCs can detect hydrocarbons at the parts per trillion levels.  Using electron capture detectors, GCs are also effective for organohalide such as chlorocarbons.
The second major technique associated with VOC analysis is mass spectrometry, which is usually coupled with GC, giving the hyphenated technique of GC-MS.
Direct injection mass spectrometry techniques are frequently utilized for the rapid detection and accurate quantification of VOCs. PTR-MS is among the methods that have been used most extensively for the on-line analysis of biogenic and anthropogenic VOCs. PTR-MS instruments based on time-of-flight mass spectrometry have been reported to reach detection limits of 20 pptv after 100 ms and 750 ppqv after 1 min. measurement (signal integration) time. The mass resolution of these devices is between 7000 and 10,500 m/Δm, thus it is possible to separate most common isobaric VOCs and quantify them independently.