The conversion of malate to pyruvate and lactate is catalyzed by
*NAD(P) dependent malate decarboxylase (malic enzyme; EC 1.1.1.39 and 1.1.1.40) and
*lactate dehydrogenase (LDH; EC 1.1.1.27)
according to the following equations:
*malate + NAD(P)→ pyruvate + NAD(P)H + H + CO
*pyruvate + NADH + H → lactate + NAD