General function of TFH:
# Initiation transcription of protein- coding gene.
# DNA nucleotide repairing.
(NER)TFH is a general transcription factor that acts to recruit RNA Pol II to the promoters of genes.  It functions as a helicase that unwinds DNA.  It also unwinds DNA after a DNA lesion has been recognized by either the global genome repair (GGR) pathway or the transcription-coupled repair (TCR) pathway of NER. Purified TFH has role in stopping further RNA synthesis by activating the cyclic peptide α-amanitin.