In organic chemistry, dehalogenation is a set of chemical reactions that involve the cleavage of carbon-halogen bonds; as such, it is the inverse reaction of halogenation. Dehalogenations come in many varieties, including defluorination (removal of fluorine), dechlorination (removal of chlorine), debromination (removal of bromine), and deiodination (removal of iodine). Incentives to investigate dehalogenations include both constructive and destructive goals. Complicated organic compounds such as pharmaceutical drugs are occasionally generated by dehalogenation.  Many organohalides are hazardous, so their dehalogenation is one route for their detoxification.