In the wake of the Castle Bravo detonation, a new research section was added to the Castle Bravo Weapons Effects research section. Program 4, "Biomedical effects," was to include one project, Project 4.1, titled "Study of Response of Human Beings exposed to Significant Beta and Gamma Radiation due to Fall-out from High-Yield Weapons." Eugene P. Cronkite of the National Naval Medical Center was designated as Project Officer. Cronkite's instructions stressed the importance of secrecy surrounding the project:
The purpose of the project, as a 1982 Defense Nuclear Agency report explained, was both medical as well as for research purposes: