Upon graduation, Floriana completed her postdoctoral research in Molecular Magnetism with Dr. Jean-Pascal Sutter at Institut de Chimie de la Matière Condensée de Bordeauxwith (ICMCB), France and also as a visiting  Deutscher Akademischer Austauschdienst (DAAD) Fellow at University of Heidelberg, Germany. She then received a Marie Curie Individual Fellowship at University of Warwick to work in supramolecular chemistry before moving to University of Manchester in 2003 as a Researcher. She was later promoted to the position of Senior Researcher. She is currently part of the Molecular Magnetism group at University of Manchester, working along with Prof. David Collison, Nicholas F. Chilton, Grigore Timco and Richard Winpenny. 
Floriana's research in general is based on inorganic chemistry and magnetochemistry, specifically on molecular magnetism, EPR spectroscopy and quantum computing.