As a strong base, TBD fully deprotonates most phenols, carboxylic acids, and some C-acids. It catalyzes a variety of reactions including Michael reactions, Henry reactions (nitroaldol reactions),  transesterification reactions, and Knoevenagel condensations.
Deprotonation at the 7-position gives a particularly electron-rich  ligand as manifested in the redox properties of ditungsten tetra(hpp).