Its activities are focused on both fundamental objectives in analytical sciences and interactions with the socio-economic environment at local, national and international levels. The Institute has partnerships with international research centers (e.g. MIT, the École Polytechnique Fédérale de Lausanne, International Agency for Research on Cancer) and national academic partners (e.g. LabexIMUST, ,  ...) and industrial partners (BioMérieux, , Sanofi, Solvay, Total) and manufacturers (Agilent, Bruker, Waters ...).
The institute is involved in competitiveness clusters (Axelera, , Techtera, Plastipolis) and regional cluster (). Some scientists are experts in standardization committees at national and European levels. In addition, the Institute of Analytical Sciences plays a «Business incubator» role and hosts start-ups: ANAQUANT, metabolomics technical platform, etc.