The Chesapeake Bay, the largest estuary in the U.S., has suffered from repeated large algal blooms for decades due to chemical runoff from multiple sources, including 9 large rivers and 141 smaller streams and creeks in parts of six states. In addition, the water is quite shallow and only 1% of the waste entering it gets flushed into the ocean.
By weight, 60% of the phosphates entering the bay in 2003 were from sewage treatment plants, while 60% of its nitrates came from fertilizer runoff, farm animal waste, and the atmosphere. About 300 million pounds (140 Gg) of nitrates are added to the bay each year. The population increase in the bay watershed, from 3.7 million people in 1940 to 18 million in 2015 is also a major factor, as economic growth leads to the increased use of fertilizers and rising emissions of industrial waste.
As of 2015, the six states and the local governments in the Chesapeake watershed have upgraded their sewage treatment plants to control nutrient discharges. The U.S. Environmental Protection Agency (EPA) estimates that sewage treatment plant improvements in the Chesapeake region between 1985 and 2015 have prevented the discharge of 900 million pounds (410 Gg) of nutrients, with nitrogen discharges reduced by 57% and phosphorus by 75%. Agricultural and urban runoff pollution continue to be major sources of nutrients in the bay, and efforts to manage those problems are continuing throughout the  watershed.