In fluid dynamics, the Knudsen equation is used to describe how gas flows through a tube in free molecular flow.  When the mean free path of the molecules in the gas is larger than or equal to the diameter of the tube, the molecules will interact more often with the walls of the tube than with each other. For typical tube dimensions, this occurs only in high or ultrahigh vacuum.
The equation was developed by Martin Hans Christian Knudsen (1871–1949), a Danish physicist who taught and conducted research at the Technical University of Denmark.