In organic chemistry, an oxime is an organic compound belonging to the imines, with the general formula , where R is an organic side-chain and R' may be hydrogen, forming an aldoxime, or another organic group, forming a ketoxime. O-substituted oximes form a closely related family of compounds. Amidoximes are oximes of amides () with general structure .
Oximes are usually generated by the reaction of hydroxylamine with aldehydes () or ketones (). The term oxime dates back to the 19th century, a combination of the words oxygen and imine.