SCORE is especially used as detection method in bio- and chemosensors. It is a label-free technique like Reflectometric interference spectroscopy (RIfS), Bio-layer Interferometry (BLI) and Surface plasmon resonance (SPR), which allows time-resolved observation of binding events on the sensor surface without the use of fluorescence or radioactive labels.
The SCORE technology was commercialised by Biametrics GmbH, a service provider and instrument manufacturer with headquarters in Tübingen, Germany. In January 2020, Biametrics GmbH and its technology was acquired by BioCopy Holding AG, headquartered in Aadorf, Switzerland.