If the two side-chains on the central carbon are different from each other—either an aldoxime, or a ketoxime with two different "R" groups—the oxime can often have two different geometric stereoisomeric forms according to the E/Z configuration. An older terminology of syn and anti was used to identify especially aldoximes according to whether the R group was closer or further from the hydroxyl.  Both forms are often stable enough to be separated from each other by standard techniques.
Oximes have three characteristic bands in the infrared spectrum, whose wavelengths corresponding to the stretching vibrations of its three types of bonds: 3600 cm (O−H), 1665 cm (C=N) and 945 cm (N−O).
In aqueous solution, aliphatic oximes are 10- to 10-fold more resistant to hydrolysis than analogous hydrazones.