Functional MRI (fMRI) has been the modality of choice to visualize brain activity, and takes advantages of a range of techniques that can be used to interpret it. However, the signal that fMRI is acquiring is BOLD signal, which does not directly correlate with blood flow. Cerebral blood flow on the other hand does, allowing for cardiovascular disease (CVD) and inflammatory risk factor analysis, and disorders (such as schizophrenia and bipolar disorder) that have comorbid effects with CVD. ASL imaging can be a useful tool to complement fMRI and vice versa.