Levomethamphetamine crosses the blood-brain-barrier and acts as a norepinephrine transporter inhibitor and TAAR1 agonist, functioning as a selective norepinephrine releasing agent (with limited effects on the release of dopamine), thus levomethamphetamine affects the central nervous system, although its effects are qualitatively distinct relative to those of dextromethamphetamine. It does not possess the same potential for euphoria or addiction that dextromethamphetamine possesses. Among its physiological effects are the vasoconstriction that makes it useful for nasal decongestion.