In Pakistan's academia and nuclear society, Qureshi was well known for his interests in classical music theory and love of playing the guitar and sitar, which he played on several occasions. He also had an interest in American poetry, which he often quoted among his peers while working on the bomb program, and played tennis avidly during his later life. He was married twice; his first wife died in the 1980s and he later remarried. He had two sons, one a neurosurgeon while the other is a computer scientist.