An example of facilitated diffusion is when glucose is absorbed into cells through Glucose transporter 2 (GLUT2) in the human body. There are many other types of glucose transport proteins, some that do require energy, and are therefore not examples of passive transport. Since glucose is a large molecule, it requires a specific channel to facilitate its entry across plasma membranes and into cells. When diffusing into a cell through GLUT2, the driving force that moves glucose into the cell is the concentration gradient. The main difference between simple diffusion and facilitated diffusion is that facilitated diffusion requires a transport protein to facilitate or assist the substance through the membrane. After a meal, the cell is signaled to move GLUT2 into membranes of the cells lining the intestines called enterocytes. With GLUT2 in place after a meal and the relative high concentration of glucose outside of these cells as compared to within them, the concentration gradient drives glucose across the cell membrane through GLUT2.