REMS scans on femur and spine last 40 and 80 seconds, respectively, allowing the acquisition of several thousands of ultrasound signals related to the skeletal site under examination. The patented algorithm (see for more details) automatically processes these signals on the basis of their spectral features; each signal can be classified as reliable and included in the pipeline for the computation of the diagnostic parameters or, alternatively, classified as unreliable and discarded. During the analysis phase, the acquired spectra are compared to the spectral models stored in the database; afterwards, the values obtained by each comparison are averaged, leading to a precise and repeatable estimation of the diagnostic parameters of interest.