Viral protein interactomes consist of interactions among viral or phage proteins. They were among the first interactome projects as their genomes are small and all proteins can be analyzed with limited resources. Viral interactomes are connected to their host interactomes, forming virus-host interaction networks. Some published virus interactomes include
Bacteriophage
* Escherichia coli bacteriophage lambda
* Escherichia coli bacteriophage T7
* Streptococcus pneumoniae bacteriophage Dp-1
* Streptococcus pneumoniae bacteriophage Cp-1
The lambda and VZV interactomes are not only relevant for the biology of these viruses but also for technical reasons: they were the first interactomes that were mapped with multiple Y2H vectors, proving an improved strategy to investigate interactomes more completely than previous attempts have shown.
Human (mammalian) viruses
* Human varicella zoster virus (VZV)
* Chandipura virus
* Epstein-Barr virus (EBV)
* Hepatitis C virus (HPC), Human-HCV interactions
* Hepatitis E virus (HEV)
* Herpes simplex virus 1 (HSV-1)
* Kaposi's sarcoma-associated herpesvirus (KSHV)
* Murine cytomegalovirus (mCMV)