Corepressor proteins also bind to the surface of the ligand binding domain of nuclear receptors, but through a LXXXIXXX(I/L) motif of amino acids (where L = leucine, I = isoleucine and X = any amino acid).  In addition, compressors bind preferentially to the apo (ligand free) form of the nuclear receptor (or possibly antagonist bound receptor).
* CtBP 602618  (associates with class II histone deacetylases)
* LCoR (ligand-dependent corepressor)
* Nuclear receptor CO-Repressor (NCOR)
** NCOR1 ()
** NCOR2 ()/SMRT (Silencing Mediator (co-repressor) for Retinoid and Thyroid-hormone receptors) (associates with histone deacetylase-3)
* Rb (retinoblastoma protein)  (associates with histone deacetylase-1 and -2)
* RCOR (REST corepressor)
** RCOR1 ()
** RCOR2 ()
** RCOR3 ()
* Sin3
** SIN3A ()
** SIN3B ()
* TIF1 (transcriptional intermediary factor 1)
** TRIM24 Tripartite motif-containing 24 ()
** TRIM28 Tripartite motif-containing 28 ()
** TRIM33 Tripartite motif-containing 33 ()