Specific characters may be used to create a suitable (ambigraphic)  nucleic acid notation  for complementary bases (i.e. guanine = b, cytosine = q, adenine = n, and thymine = u), which makes it is possible to complement entire DNA sequences by simply rotating the text "upside down".  For instance, with the previous alphabet,  (GTCA) would read as  (TGAC, reverse complement) if turned upside down.
Ambigraphic notations readily visualize complementary nucleic acid stretches such as palindromic sequences. This feature is enhanced when utilizing custom fonts or symbols rather than ordinary ASCII or even Unicode characters.