Wiesner received a Guggenheim Fellowship in 1952, the Chemical Institute of Canadas Palladium Medal in 1963, the Royal Society of Chemistrys Centenary Prize in 1976, the American Chemical Society's Ernest Guenther Award in 1983, and the Izaak Walton Killam Memorial Prize in 1986. He was elected to the Royal Society of Canada in 1957, to the Royal Society in 1969, and admitted to the Pontifical Academy of Sciences in 1978. He was awarded the Order of Canada on June 25, 1975. He also received the Marin Drinov Medal of the Bulgarian Academy of Sciences.