* TEs are also a widely used tool for mutagenesis of most experimentally tractable organisms. The Sleeping Beauty transposon system has been used extensively as an insertional tag for identifying cancer genes.
* The Tc1/mariner-class of TEs Sleeping Beauty transposon system, awarded Molecule of the Year in 2009, is active in mammalian cells and is being investigated for use in human gene therapy.
* TEs are used for the reconstruction of phylogenies by the means of presence/absence analyses. Transposons can act as biological mutagen in bacteria.
* Common organisms which the use of Transposons has been well developed are:
**Drosophila
** Arabidopsis thaliana
** Escherichia coli