FDA launched HIVE Open Source as a platform to support end to end needs for NGS analytics. 
https://github.com/FDA/fda-hive
HIVE biocompute harmonization platform is at the core of High-throughput Sequencing Computational Standards for Regulatory Sciences (HTS-CSRS) project. Its mission is to provide the scientific community with a framework to harmonize biocomputing, promote interoperability, and verify bioinformatics protocols (https://hive.biochemistry.gwu.edu/htscsrs). For more information, see the project description on the FDA Extramural Research page (https://www.fda.gov/ScienceResearch/SpecialTopics/RegulatoryScience/ucm491893.htm