Ibuprofen was made available by prescription in the United Kingdom in 1969 and in the United States in 1974.
Ibuprofen is the International nonproprietary name (INN), British Approved Name (BAN), Australian Approved Name (AAN) and United States Adopted Name (USAN). In the United States, it has been sold under the brand-names Motrin and Advil since 1974 and 1984, respectively. Ibuprofen is commonly available in the United States up to the FDA's 1984 dose limit OTC, rarely used higher by prescription.
In 2009, the first injectable formulation of ibuprofen was approved in the United States, under the brand name Caldolor.
Ibuprofen can be taken orally (by mouth) (as a tablet, a capsule, or a suspension) and intravenously.