Ionic strength determines the Debye length that correlates with the damping distance of the electric potential of a fixed charge in an electrolyte. So, higher the ionic strength the shorter are electrostatic interactions between charged entities. As a result, the adsorption of charged proteins to oppositely charged substrates is hindered whereas the adsorption to like charged substrates is enhanced, thereby influencing adsorption kinetics. Also, high ionic strength increases the tendency of proteins to aggregate.