Despite their many advantages, the use of PPGs in total syntheses are relatively rare. Nevertheless, PPGs’ "orthogonality" to common synthetic reagents, as well as the possibility of conducting a "traceless reagent process", has proven useful in natural product synthesis. Two examples include the syntheses of ent-Fumiquinazoline and (-)-diazonamide A. The syntheses required irradiation at 254 and 300 nm, respectively.