Ankyrin repeat and kinase domain containing 1 (ANKK1) also known as protein kinase PKK2 or sugen kinase 288 (SgK288) is an enzyme that in humans is encoded by the ANKK1 gene.  The ANKK1 is a member of an extensive family of the Ser/Thr protein kinase family, and protein kinase superfamily  involved in signal transduction pathways.