Isla San José is the second largest island in the Pearl Islands, off the Pacific coast of Panama. The privately owned island has an area of . At the 2000 census, it had a population of only 10. Thousands of wild pigs and deer populate Isla San Jose, which has a rugged, rocky shoreline and over 50 beaches.
A unit of U.S. soldiers tested chemical arms from 1945 to 1947 on the then deserted island, leaving behind at least eight unexploded 500 and 1,000-pound bombs. A U.S. military text states that the larger bombs contained phosgene and cyanogen chloride, and smaller ones mustard gas. Other reports state that the soldiers also tested VX nerve gas and sarin. Claims of abandoned mine fields containing thousands of armed chemical mines have been made, but no evidence of this has been presented. An unknown but large amount of munitions was also dropped into the sea around the island. Earl Tupper, the inventor of Tupperware, was owner of the island.  
The island is served by San José Airport.