The Hawaii Ocean Time-series (HOT) program is a long-term oceanographic study based at the University of Hawaii at Manoa. In 2015, the American Society for Microbiology designated the HOT Program's field site Station ALOHA (A Long-Term Oligotrophic Habitat Assessment; ()) a "Milestone in Microbiology", for playing "a key role in defining the discipline of microbial oceanography and educating the public about the vital role of marine microbes in global ecosystems." 
Scientists working on the Hawaii Ocean Time-series (HOT) program have been making repeated observations of the hydrography, chemistry and biology of the water column at a station north of Oahu, Hawaii since October 1988. The objective of this research is to provide a comprehensive description of the ocean at a site representative of the North Pacific Subtropical Gyre. Cruises are made approximately once per month to the deep-water Station ALOHA located 100 km north of Oahu, Hawaii. Measurements of the thermohaline structure, water column chemistry, currents, optical properties, primary production, plankton community structure, and rates of particle export are made on each cruise. The HOT program also uses autonomous underwater vehicles, including floats and gliders, to collect data at Station ALOHA between cruises.