A classic example of vinylogy is the relatively high acidity of the γ-hydrogen in .  The acidity of the terminal methyl group is similar to that for the methyl ketone .
Vinylogous reactions also include conjugate additions, where a nucleophile reacts at the vinyl terminus, akin to the addition of the nucleophile to the carbonyl of the methyl ketone. In a vinylogous variation of the aldol reaction, an electrophile is attacked by a nucleophilic vinylogous enolate (see first and following image). The vinylogous enolate reacts at the terminal position of the double bond system (the γ-carbon), rather than the α-carbon immediately adjacent to the carbonyl, as would a simple enolate. Allylic electrophiles often react by vinylogous attack of a nucleophile rather than direct addition.
A further example of vinylogous reactivity: ascorbic acid (Vitamin C) behaves as a vinylogous carboxylic acid by involvement of its carbonyl moiety, a vinyl group within the ring, and the lone pair on the hydroxyl group acting as the conjugated system. Acidity of the hydroxyl proton at the terminus of the vinyl group in ascorbic acid is more comparable to a typical carboxylic acid than an alcohol because two major resonance structures stabilize the negative charge on the conjugate base of ascorbic acid (center and right structures in last image), analogous to the two resonance structures that stabilize the negative charge on the anion that results from removal of a proton from a simple carboxylic acid (cf. first image). Analogously, sorbic acid derivatives, extended by another "vinyl" moiety show vinylogous behaviour as well.  
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