* Chromatin structure oriented factors:<br />(HMTs (Histone MethylTransferases)):<br /> COMPASS§† – (COMplex of Proteins ASsociated with Set1) – Methylates lysine 4 of histone H3: Is responsible of repression/silencing of transcription. A normal part of cell growth and transcription regulation within RNAP II.
* Set2 – Methylates lysine 36 of histone H3: Set2 is involved in regulation transcription elongation through its direct contact with the CTD.<br /> (interesting irrelevant example: Dot1*‡ – Methylates lysine 79 of histone H3.)
* Bre1 – Ubiquinates (adds ubiquitin to) lysine 123 of histone H2B. Associated with pre-initiation and allowing RNA Pol II binding.