*Microarray-Based Study by Metal Nanoparticle Probes
Recently, studies by using metal nanoparticle probes to detect the carbohydrate–protein interactions were reported. Use of gold and silver nanoparticle probes in resonant light scattering (RLS) gives particular high sensitivity. Zhenxin Wang and coworker the same principle applied this method to detect the interaction between carbohydrate and protein.
*Carbohydrate biosensor
As Lectin can strongly bind to specific carbohydrate, scientists develop several lectin-based carbohydrate biosensors.  Designed lectin contains specific groups can be detected by analytical method.
*Isothermal Titration Calorimetry