In the ovary, the FSH receptor is necessary for follicular development and expressed on the granulosa cells.
In the male, the FSH receptor has been identified on the Sertoli cells that are critical for spermatogenesis.
The FSHR is expressed during the luteal phase in the secretory endometrium of the uterus.
FSH receptor is selectively expressed on the surface of the blood vessels of a wide range of carcinogenic tumors.