Actaplanin is a complex of broad-spectrum antibiotics made by Actinoplanes bacteria. Research carried out by a group in Eli Lilly and Co. in 1984 identified several actaplanins using high-performance liquid chromatography. Actaplanins A, B, B, B, C and G were shown to be composed of the same peptide core, an amino sugar, and varying amounts of glucose, mannose, and rhamnose.