The single survivin gene can give rise to four different alternatively spliced transcripts:
# Survivin, which has a three-intron–four-exon structure in both the mouse and human.
# Survivin-2B, which has an insertion of an alternative exon 2.
# Survivin-Delta-Ex-3, which has exon 3 removed. The removal of exon 3 results in a frame shift that generates a unique carboxyl terminus with a new function. This new function may involve a nuclear localization signal. Moreover, a mitochondrial localization signal is also generated.
# Survivin-3B, which has an insertion of an alternative exon 3.