SBPase and FBPase (fructose-1,6-bisphosphatase, EC 3.1.3.11) are both phosphatases that catalyze similar during the Calvin cycle. The genes for SBPase and FBPase are related. Both genes are found in the nucleus in plants, and have bacterial ancestry. SBPase is found across many species. In addition to being universally present in photosynthetic organism, SBPase is found in a number of evolutionarily-related, non-photosynthetic microorganisms. SBPase likely originated in red algae.