谱图库搜索策略直接比较实验谱图与谱图库中的真实谱图，充分利用了谱图中的丰度、非常规碎裂模式和其他的一些特征，使得搜索更加快速和准确，成为蛋白质组学的主流鉴定方法之一。
Nowadays, the spectral library searching has become a mature strategy for tandem mass spectra based proteins identification in proteomics, which searches the experiment spectra against a collection of confidently identified MS/MS spectra that have been observed previously, and fully utilizes the abundance in the spectrum, peaks from non-canonical fragment ions, and other features.