Statement: One patient in cohort 2 of the primary trial crashed their motorbike.
Primary_evidence: Adverse Events 1:   Total: 12/538 (2.23%)   Hypertension 0/538 (0.00%)   Acoustic Neuroma 1/538 (0.19%)   Diarrhea 0/538 (0.00%)   Colitis 1/538 (0.19%)   Elevated ALT or AST enzyme 7/538 (1.30%)   Diagnosis of Uterine Cancer 0/538 (0.00%)   Motorcycle accident 0/538 (0.00%)   Fall 0/538 (0.00%)   Surgery 3/538 (0.56%) Adverse Events 2:   Total: 8/537 (1.49%)   Hypertension 1/537 (0.19%)   Acoustic Neuroma 0/537 (0.00%)   Diarrhea 1/537 (0.19%)   Colitis 0/537 (0.00%)   Elevated ALT or AST enzyme 0/537 (0.00%)   Diagnosis of Uterine Cancer 2/537 (0.37%)   Motorcycle accident 1/537 (0.19%)   Fall 1/537 (0.19%)   Surgery 2/537 (0.37%)