Statement: the primary trial and the secondary trial do not explain their interventions in the intervention section.
Primary_evidence: INTERVENTION 1:    MM-111 All participants
Secondary_evidence: INTERVENTION 1:    Arm I (Low-dose Omega-3 Fatty Acid)   Patients receive low-dose omega-3 fatty acid supplementation PO BID and placebo PO BID for 6 weeks. Omega-3 Fatty Acid: Given PO   Placebo: Given PO   Questionnaire Administration: Ancillary studies   Laboratory Biomarker Analysis: Correlative studies INTERVENTION 2:    Arm II (High-dose Omega-3 Fatty Acid)   Patients receive high-dose omega-3 fatty acid supplementation PO BID for 6 weeks. Omega-3 Fatty Acid: Given PO   Questionnaire Administration: Ancillary studies   Laboratory Biomarker Analysis: Correlative studies