Statement: Patients currently prescribed Diuretics are excluded from the primary trial.
Primary_evidence: Inclusion Criteria:   unilateral breast cancer with ipsilateral lumpectomy or mastectomy and lymph node dissection (sentinel biopsy or axillary dissection)   stage II or III unilateral secondary upper extremity lymphedema (as defined by the International Society of Lymphology)   girth  2 cm circumferential difference and/or volume  200 mL compared to the uninvolved upper extremity at any 4 cm segment   able to commit to a long term follow-up schedule Exclusion Criteria:   active cancer/metastatic cancer   currently receiving or have plans for adjuvant radiation or chemotherapy   pregnant   presence of other extremity lymphedema (primary or secondary)   pacemaker   artificial joints in the upper quadrants   renal failure   arterial insufficiency   congestive heart failure   chronic inflammatory conditions   history of deep vein thrombosis (DVT) in the lymphedematous upper extremity   previous treatment with Low Level Laser (regardless of indication)   medication(s) known to affect body fluid balance   body mass index (BMI) > 40 (morbid obesity)