Statement: Patients with prior chemotherapy are excluded from the secondary trial and the primary trial.
Primary_evidence: Inclusion Criteria:   Female subjects participating in FMSU004A protocol with known clinical status Exclusion Criteria:   Subjects with unknown clinical status not participating in FMSU004A protocol.
Secondary_evidence: Inclusion Criteria:   To be included in this study, you must meet the following criteria:   Locally advanced/inflammatory adenocarcinoma of the breast   18 years of age or older   Normal heart function   Able to perform activities of daily living with minimal assistance   No prior chemotherapy for breast cancer   Adequate bone marrow, liver and kidney function   No evidence or history of significant cardiovascular abnormalities   Sentinel node or axillary dissection   Sign an informed consent form Exclusion Criteria:   You cannot participate in this study if any of the following apply to you:   Pregnant or breast feeding   History of heart disease with congestive heart failure   Heart attack within the previous 6 months   Prior chemotherapy or hormone therapy for breast cancer   History of active uncontrolled infection   Please note: There are additional inclusion/exclusion criteria. The study center will determine if you meet all of the criteria. If you do not qualify for the trial, study personnel will explain the reasons. If you do qualify, study personnel will explain the trial in detail and answer any questions you may have.