Statement: Patients are not required to be sexually active to receive the primary trial intervention, this is however a requirement for the secondary trial where the intervention must be applied during sexual activity.
Primary_evidence: INTERVENTION 1:    No Exercise   Multivitamin Arm + Calcitriol Arm:Calcitriol pill taken once per week INTERVENTION 2:    Exercise   Exercise Arm: Exercise consisting of progressive walking and resistance band training   Calcitriol+ Exercise Arm: Calcitriol pill taken once per week + Exercise
Secondary_evidence: INTERVENTION 1:    AB-101   Apply to both nipple/areola regions approximately 1 hour prior to sexual activity   AB-101: Apply approximately 1 hour prior to sexual activity INTERVENTION 2:    Placebo   Apply to both nipple/areola regions approximately 1 hour prior to sexual activity   Placebo: Apply approximately 1 hour prior to sexual activity