Statement: Clinically anxious patients are not able to participate in the primary trial.
Primary_evidence: Inclusion Criteria:   At least 18 years of age   Willing and able to provide informed consent   Reporting daily hot flashes   Able to read, write, and speak English   Postmenopausal to limit sample variability (> 12 months amenorrhea)   Greater then 1 month but < 5 years post-treatment (surgery, radiation, chemotherapy) for non-metastatic breast cancer.   These criteria allow inclusion of women successfully treated for recurrent breast cancer since there is no known reason to exclude them. Menopausal status is assessed using self-reports due to problems in reliably measuring follicle-stimulating hormone levels and estradiol in tamoxifen users. Exclusion Criteria:   Exclusion criteria are current depression, history of migraines or hepatitis, abnormal chemistry profile (e.g., sodium, potassium, glucose), or a positive urine drug screen for illegal substances.