Statement: CO2 is utilised as part of the intervention in a single one of the study groups in the primary trial, and not used in either of the study groups in the secondary trial.
Primary_evidence: INTERVENTION 1:    AeroForm Tissue Expansion   AeroForm Tissue Expansion inflation with carbon dioxide by remote control   AeroForm Tissue Expansion: The AeroForm Patient Controlled Tissue Expander is a breast tissue expander implanted following mastectomy and activated by remote control to release small doses of carbon dioxide from an internal reservoir to fill and inflate the expander. INTERVENTION 2:    Saline Tissue Expansion   Saline Tissue Expansion inflated by needle injections of saline   Saline Tissue Expansion: A saline tissue expander is a breast tissue expander which is implanted following mastectomy and inflated over time using needle injections to fill and inflate the expander with saline.
Secondary_evidence: INTERVENTION 1:    FFDM and DBT   FFDM exam and DBT scan on Siemens MAMMOMAT Inspiration INTERVENTION 2:    FFDM Only FFDM exam only