Statement: participants of cohort 1 in the primary trial and all participants of the secondary trial take 1 milligram of anastrozole PO QD.
Primary_evidence: INTERVENTION 1:    Arimidex Group   Anastrozole(ARIMIDEX): 1 mg once daily oral dose INTERVENTION 2:    TAM Group   Tamoxifen : 20 mg once daily oral dose
Secondary_evidence: INTERVENTION 1:    Anastrozole and Simvastatin   adjuvant therapy : laboratory analysis   pharmacological study : laboratory analysis   simvastatin : 40 milligram tablet PO QD for 14 days   anastrozole : 1 milligram tablet PO QD for 14 days