Statement: Adequate Hematologic, Hepatic and renal function is not necessary for participating in the primary trial. However, being pregnant is required.
Primary_evidence: Inclusion Criteria:   stage I-III breast cancer   adjuvant or neoadjuvant anthracycline-based chemotherapy Exclusion Criteria:   under age 18   pregnancy   metastatic or inoperable (including inflammatory) breast cancer   confounding underlying medical illnesses   history of mania   history of other axis-I psychiatric disorder   other physical or psychological impairments -