Statement: patients participating in the primary clinical trial receive a greater dosage of bkm120 than those in the secondary clinical trial
Primary_evidence: INTERVENTION 1:    BKM120 and Paclitaxel   Adult females with histologically confirmed, inoperable, locally advanced or metastatic HER2- BC who received study drug plus paclitaxel INTERVENTION 2:    Placebo and Paclitaxel   Adult females with histologically confirmed, inoperable, locally advanced or metastatic HER2- BC who received placebo plus paclitaxel
Secondary_evidence: INTERVENTION 1:    Active Breathing Coordinator   Patients breathe through the ABC device   Active Breathing Coordinator (ABC) : The generated dose distributions from the free-breathing versus ABC plans will be compared to assess the volume of normal tissue, as well as target volume irradiated, utilizing dose-volume histograms.