Statement: low cardiac output is a below normal volume of blood pumped from the right or left ventricle of the heart per unit time. All the primary trial participants are administered flaxseed, but none of the secondary trial receive any flaxseed.
Primary_evidence: INTERVENTION 1:    Arm A - Flaxseed & Active Anastrazole   25 mg flaxseed per day and 1 mg anastrozole pill per day   Anastrozole: 1 mg per day   flaxseed: 25 g per day ground INTERVENTION 2:    Arm B - Flaxseed   Flaxseed 25 mg per day and 1 placebo pill per day   flaxseed: 25 g per day ground
Secondary_evidence: INTERVENTION 1:    Phase 1 - Cohort A   Dual treatment with 1 mg anastrozole orally once daily together with AZD0530 175 mg orally once daily, or as specified per protocol, until disease progression for treatment of metastatic breast cancer   Anastrozole AZD0530