Statement: eliane is a 56 year old woman, and elizabeth is a 32 year old woman, both eliane and elizabeth can both be eligible for the primary trial
Primary_evidence: Inclusion Criteria:   women >=18 years of age;   newly diagnosed;   infiltrating (invasive) HER2-neu-negative or HER2-neu-positive breast cancer. Exclusion Criteria:   evidence of metastatic disease, except ipsilateral (same side) axillary lymph nodes;   previous systemic or local primary treatment.