Statement: eliane, at 56 years old, is not eligible for the primary clinical trial
Primary_evidence: Inclusion Criteria:   women >=18 years of age;   newly diagnosed;   infiltrating (invasive) HER2-neu-negative or HER2-neu-positive breast cancer. Exclusion Criteria:   evidence of metastatic disease, except ipsilateral (same side) axillary lymph nodes;   previous systemic or local primary treatment.