human
What's the best way to remove a stain from my favorite shirt?
assistant
The best way to remove a stain from your favorite shirt is by pre-treating it with a stain remover or detergent before washing. If the stain persists, you may need to use an enzyme-based cleaner specifically designed for removing certain types of stains. Additionally, if the stain is particularly tough, you can try soaking the garment in cold water and then using a soft brush to scrub the stain away.