human
What's the best way to remove a stain from my shirt?
assistant
The best way to remove a stain from your shirt is to pre-treat it with a laundry detergent and cold water, then wash on the hottest setting possible. If that doesn't work, you can try using an enzyme-based cleaner or spot remover specifically designed for clothing. Finally, if all else fails, you can always handwash the item in cool water and use a mild detergent.