human
Is it safe to take ibuprofen with aspirin?
assistant
Yes, it is safe to take ibuprofen and aspirin together. Aspirin works by blocking the enzyme cyclooxygenase (COX) which is responsible for producing prostaglandins, which are inflammatory chemicals that cause pain. Ibuprofen works by inhibiting COX-2, another type of prostaglandin synthase. Taking ibuprofen and aspirin together can reduce inflammation and provide more relief from pain than either drug alone.