<diacritize> According to speech therapists Mirtha Manno and Ruben Delauro , who manage a self - help clinic called Smiling and Health , the mere gesture of smiling produces an electrical stimulus that affects the pituitary gland . <yor>According to speech therapists Mirtha Manno and Rubén Delauro , who manage a self - help clinic called Smiling and Health , the mere gesture of smiling produces an electrical stimulus that affects the pituitary gland . 