<prompt> Ke kotsi efe e kholo ka ho fetisisa ea ho tšoaroa ke lefu la methapo ea pelo?nan  <response>: Instruction in English: What is the biggest risk factor for developing coronary artery disease? . Response in English: The biggest risk factor for developing coronary artery disease CAD is having high levels of low-density lipoprotein LDL cholesterol. LDL cholesterol is commonly known as bad cholesterol because it contributes to the buildup of plaque in your arteries, which increases the risk of CAD. Apart from having high LDL cholesterol levels, other major risk factors of developing CAD include high blood pressure, diabetes, smoking tobacco, sedentary lifestyle, family history of heart disease, and being overweight or obese. . Response in Sesotho: Lebaka le leholo ka ho fetisisa la kotsi ea ho tšoaroa ke lefu la methapo ea pelo CAD ke ho ba le kholeseterole e phahameng ea low-density lipoprotein LDL. Kholeseterole ea LDL hangata e tsejoa e le kholeseterole e mpe hobane e tlatsetsa ho bokelleng ha letlapa methapong ea hao, e leng ho eketsang kotsi ea CAD. Ntle le ho ba le kholeseterole e phahameng ea LDL, lisosa tse ling tse khōlō tsa kotsi ea ho tšoaroa ke CAD li akarelletsa khatello e phahameng ea mali, lefu la tsoekere, ho tsuba koae, mokhoa oa bophelo oa ho lula feela, histori ea lelapa ea lefu la pelo le ho ba boima bo feteletseng kapa botenya. 