<prompt> Hlalosa hore na lefu le fanoeng le bakoa joang.Anencephaly  <response>: Instruction in English: Explain how the given disease is caused. . Response in English: Anencephaly is a neural tube defect that occurs early in the development of an unborn baby. It happens when the upper part of the neural tube, the structure in an embryo that eventually developes into the brain and spinal cord , fails to close properly. As a result, the baby is born missing larger parts of the brain, skull, and scalp. The exact cause of anencephaly is unknown, but certain genes, environmental factors, and nutritional deficiencies like a lack of folic acid in the mothers diet are thought to play a role. Since the brain is missing, babies with anencephaly are usually stillborn, or die shortly after birth. . Response in Sesotho: Anencephaly ke bofokoli ba methapo ea kutlo bo hlahang qalong ea tsoelo-pele ea lesea le e-so tsoaloe. E etsahala ha karolo e ka holimo ea neural tube, sebopeho se ka hara lesea le sa tsoa emoloa le qetellang le kena bokong le lesapo la mokokotlo, le hlōleha ho koala hantle. Ka lebaka leo, lesea le hlaha le se na likarolo tse khōloanyane tsa boko, lehata le letlalo la hlooho. Ha e le hantle, sesosa sa lefu la anencephaly ha se tsejoe, empa ho nahanoa hore liphatsa tsa lefutso tse itseng, maemo a tikoloho, le khaello ea phepo e nepahetseng joaloka khaello ea asiti ea folic lijong tsa ma li phetha karolo e itseng. Kaha boko bo haella, bana ba nang le anencephaly hangata ba hlaha ba shoele, kapa ba shoa nakoana ka mora ho hlaha. 