<prompt> Hlalosa hore na phekolo ea liphatsa tsa lefutso e sebetsa joang.nan  <response>: Instruction in English: Explain how gene therapy works. . Response in English: Gene therapy involves introducing new genetic material into cells to help combat or prevent diseases. This is usually done with a virus, which acts as a delivery vehicle or vector, to carry the therapeutic gene into the cells. The virus is genetically modified to be safe for use in humans and to effectively deliver the gene. Once the virus enters the cells, its genetic material is integrated into the host cells DNA. This allows the new gene to start producing its protein or to influence the activity of other genes. The goal of this is often to replace or supplement the function of a gene that is missing or not working correctly. This can help to treat conditions caused by gene defects, such as hemophilia, where the body does not produce enough of a blood clotting factor.There are also other methods to deliver the genetic material, such as using a plasmid, a small, circular piece of DNA that can be taken up by the cells. Additionally, the genetic material can be delivered directly to the cells using physical methods, such as electroporation, which uses an electric field to make the cell membrane more permeable, allowing the DNA to enter.Gene therapy is still a relatively new field with ongoing research and development, but it holds a lot of potential for the treatment of genetic disorders and other diseases. . Response in Sesotho: Phekolo ea liphatsa tsa lefutso e kenyelletsa ho hlahisa liphatsa tsa lefutso tse ncha liseleng ho thusa ho loantsa kapa ho thibela mafu. Hangata sena se etsoa ka kokoana-hloko, e sebetsang e le koloi ea pelehi kapa vector, ho kenya lefutso la phekolo liseleng. Kokoana-hloko e fetotsoe ka liphatsa tsa lefutso hore e bolokehe ho sebelisoa ho batho le ho fana ka phatsa ea lefutso ka katleho. Hang ha kokoana-hloko e kena liseleng, liphatsa tsa lefutso tsa eona li kenngoa ho DNA ea sele e amohelang. Sena se lumella jini e ncha hore e qale ho hlahisa protheine ea eona kapa ho susumetsa tšebetso ea liphatsa tse ling tsa lefutso. Sepheo sa sena hangata ke ho nkela sebaka kapa ho tlatsetsa tšebetsong ea liphatsa tsa lefutso tse sieo kapa tse sa sebetseng hantle. Sena se ka thusa ho alafa maemo a bakoang ke bofokoli ba liphatsa tsa lefutso, joaloka haemophilia, moo mele o sa hlahiseng karolo e lekaneng ea ho hoama mali. Ho boetse ho na le mekhoa e meng ea ho fana ka liphatsa tsa lefutso, tse kang ho sebelisa plasmid, karoloana e nyenyane, e chitja ea DNA e ka nkoang ke lisele. Ho feta moo, liphatsa tsa lefutso li ka fetisetsoa liseleng ka kotloloho ho sebelisoa mekhoa ea mele, joalo ka electroporation, e sebelisang sebaka sa motlakase ho etsa hore lera la sele le kenelle haholoanyane, ho lumella DNA ho kena. Phekolo ea liphatsa tsa lefutso e ntse e le tšimo e ncha e nang le lipatlisiso le ntsetsopele e tsoelang pele, empa e na le menyetla e mengata ea phekolo ea mafu a lefutso le mafu a mang. 