Below is the list of tables from the database along with their columns and datatype. Need to generate an accurate SQL query for the question.
Only use the columns present in the respective table. Only use the columns which are required to generate the SQL query. Only use table joins if required and not otherwise.

### Tables ###
TABLE: CREATE TABLE medicine ( name VARCHAR, trade_name VARCHAR )
TABLE: CREATE TABLE enzyme ( id VARCHAR, product VARCHAR )
TABLE: CREATE TABLE medicine_enzyme_interaction ( medicine_id VARCHAR, enzyme_id VARCHAR )

### Question ###
Show the medicine names and trade names that cannot interact with the enzyme with product 'Heme'.

### Accurate SQL ###

SELECT name, trade_name FROM medicine EXCEPT SELECT T1.name, T1.trade_name FROM medicine AS T1 JOIN medicine_enzyme_interaction AS T2 ON T2.medicine_id = T1.id JOIN enzyme AS T3 ON T3.id = T2.enzyme_id WHERE T3.product = 'Protoporphyrinogen IX'