have started using this after years of constant problems with sluggish gallbladder and gallstones. An earlier post said that all you really needed was milk thistle and that the other items do not help at all. I can honestly say that after years of my own research, the methionine and choline and dandelion are a definite help to my gallbladder problems and to find them all combined in this one product is wonderful. It also contains pancreatin which is a great help to the digestion process and helps to take stress of the gallbladdera great product