It took me about 2 weeks to get used to this keyboard because I went straight from a standard flat keyboard to this higher, split/ergonomic one. It freaked me out at first, but 1 month later, roughly, I could hardly type on a standard keyboard, nor did I want to! I'm a medical transcriptionist and I type A LOT. I love the "Favorites" keys and the Zoom in the middle. I don't know what I'd do without the Back and Forward buttons; I use them ALL the time to "surf" and use them going through folders, too. The Enter button is smaller, which I didn't care for, but I've adjusted. I do still have trouble with "p" at times, though; I think that's due to my short fingers ;o). It doesn't fit well on my desk (the slide-out keyboard holder), but I'd much rather buy another desk than go back to a regular old keyboard. I cannot do without this keyboard now! My typing speed has increased and my wrists and shoulders don't hurt me anymore. Absolutely love it!