**Spoilers**What you have here is a slowly paced movie, that jumps around a lot, and does not have a definite conclusion. This is a recipe that some people will simply not like.I loved the fact that it's open to my interpretation, the movie doesn't let you know for sure what's real and what's imagined.My take is this: The entire movie takes place in present time, and there is no "Tree of Life". The past and future versions of the characters are from Izzi's book. Tom is spending all his time working and trying to find a cure for his wife's terminal disease, not realizing what's important, which is spending time with his dying wife. She can accept the fact that she'll die, he thinks that death is a disease that can be cured, it isn't until the end of the movie that he understands that he needs to accept death, his wife's and eventually his own.I really enjoyed this movie. After it was over, I got kind of a "I liked that, but I don't know why" feeling.