So disappointed it made me sick from the first dose. Nausea, burping and abdominal pain. I tried it with and without food, in the morning, at bedtime, etc. I truly have a very sensitive stomach and this product made me very ill. It was a week after I stopped taking it that my stomach got back to normal. Beware that the manufacturer, Flora does not stand behind this product and Vitamin Discount Center does not accepts returns of opened products. You cannot return it or receive credit if you are unhappy.