I have read that research now states that both Tocopherols & Tocotrienols need to be present in a Vitamin E supplement in order to be effective. So I will use up the plain Vitamin E I have now as a moisturizer. Just break or cut open the capsule and apply. Because I have heart disease I need both the tocopherols and tocotrienols or I am just wasting my money. That is true for any oral Vitamin E supplement that does not have this mix it is a waste of money.