Does not work at all with asus maximus IV gene-Z motherboards. Does not recognize connection at all. I tried three of them, on three machines. No luck. The little cube type adapter gets recognised, but doesn't work properly (see my review of that one on it's review list). I'm almost ready to spring for a custom adapter or new klicky motherboard, I'll be able to afford it by selling my nice fancy black IBM M motherboard with trackpoint.