in general, poorly written(reads like a first draft), but the first few chapters held my attention. i thought that it was a good and easy to read exposition of a serious biological/medical/envirnmental/public health/public policy issue, but as i read on i began to lose confidence in the accuracy/value/significance of what i was reading. the author progressively added more and more of his own opinion to the facts, often without making the distinction. i'm interested in reality, not the author's personal politics.too much idolization of Gladjusek(except he writes that Gladjusek is a pedaphile, after which he dismisses it as not being significant[so why mention it at all]) and too much villification of Prusiner. these flaws made me begin to question the accuracy/value/significance of everything that he posits as fact. this books starts out reading like the Scientific American and ends up reading like the National Enquirer.i'd love to own the movie rights.