Have taken many different brands of digestive enzymes (pancreatic emphasis) for several years and decided to try these as the price is more reasonable than many other brands and the formulary got good reviews. However, even though I had nothing but positive expectations, my poor digestive symptoms returned. I then tried doubling up --- still not doing the job. Cannot recommend, as after a week all my negative symptoms which have been held at bay (upset, bloating, gas, irreg., etc.) are returning.