DRM simply means Digital Rights Management. You have to have an internet connection for initial activation, and you cannot activate the game more than three times. I knocked off a star in my review because of this DRM, but I would not rate the game only a star as many are doing. The actual game is awesome! Really awesome! If you like Sim City 4, then this is for you. NOT AN RPG! THIS IS A SIMULATION GAME! I found the cell stage to be easy fun, while the space stage was hard, and full of things going on. (Kind of frustrating at times.) The game has some glitches, but the overall experience was fantastic! You get to control cells you create, as well as creatures. You also get to command the actions of a tribe, and create cities. Finally, you create your own spaceship, and travel the galaxy! Have not tried the internet feature, so I cannot comment on that. Great game, lots of fun. Period.