Attempted to use it with my Harmony 1000. It works for ~ 5 minutes right after updating both the remote and the extender from the computer, then stops working. The little "sending RF signal" icon does flash on the remote, but the extender does not seem to receive any signals whatsoever. Nothing gets it working again (rebooting the extender, rebooting the remote, pressing connect on the extender, etc.) -- except re-upating both the remote and extender via USB from the computer. Then it works again for ~ 5 minutes. I doubt it has to do with interference, since I am performing my tests with the remote right next to the extender. Of course, I have updated both the remote and extender with the latest firmware.I do like everything else about the H1000, and the IR works fine, so now I'm desperately seeking an alternative RF solution for that remote.