The box accomodates just about every expansion of dominion. I currently filled this box with every card from Base_Dominion, Prosperity, Hinterlands, Intrigue, Seaside, and Dark Ages. I have the cards sorted alphabetically using BCW divider cards. With roughly 2300 cards, extra game pieces and manuals, this box may even be able to accomodate the 2 expansions I don't have and an announced expansion that hasn't come out yet. It's not a perfect organizational system but it does the job just fine.