This program seems to depend on components in IE5.5. I had IE5.5 already installed, but Picture It still did not seem to install correctly, yielding multiple scripting errors every time I launched the program or tried to access the "Start page". The Readme file was unhelpful. As the first reviewer indicated, the installer does not allow you to reinstall on top of an existing installation (!) but I did resort to uninstalling and reinstalling. I also reinstalled IE. No luck.