Bought this for a lab that I rescued which had a lot of anxiety issues (separation anxiety, pacing the house for hours, refusing to lay down and rest, following us from room to room, crying when he would see another dog). The DAP didn't seem to work at all.We recently put him on a prescription anti-depressant (Clomicalm) and it is a complete 180* change within 2 weeks. He is much more relaxed, sociable, and fun.DAP is worth a shot but if it doesn't work I definitely recommend trying a more aggressive option (Clomicalm).