My Miniature Schnauzer had been suffering from dermatisus or something itchy for years. The only relief he got was his ONCE A YEAR Prednisone shot, because I know how toxic it is. Anyway, I got this and can't believe it is working so well. I do the whole shooting gallery of Nzymes, grain free food, and special shampoos, and this little $8 bottle works. I do wish it came in a larger size.