---
license: apache-2.0
tags:
- flow-matching
- diffusion
- generative-ai
- biology
- chemistry
pipeline_tag: other
library_name: pytorch
---
## ⚡️ReQFlow: Rectified Quaternion Flow for Efficient and High-Quality Protein Backbone Generation
[](https://arxiv.org/abs/2502.14637)[](https://github.com/AngxiaoYue/ReQFlow)[](https://huggingface.co/AngxiaoYue/ReQFlow/tree/main)
Our **ReQFlow** achieves **state-of-the-art (SOTA)** performance 🎯 in protein backbone generation while requiring significantly fewer sampling steps and substantially reducing inference time. For example, it is **37×** faster than RFDiffusion and **62×** faster than Genie2 when generating a backbone of length 300, demonstrating both its effectiveness and efficiency 🚀🚀🔥.
Ready to dive in? We’ve got checkpoints and step-by-step guides to get you inferencing in no time—playtime starts now! ✨
## 🚀🚀🔥
🔗arxiv link: [https://arxiv.org/abs/2502.14637](https://arxiv.org/abs/2502.14637)
🌳github link: [https://github.com/AngxiaoYue/ReQFlow](https://github.com/AngxiaoYue/ReQFlow)